Filtyp
BACKGROUND: The explosion in biological information creates the need for databases that are easy to develop, easy to maintain and can be easily manipulated by annotators who are most likely to be biologists. However, deployment of scalable and extensible databases is not an easy task and generally requires substantial expertise in database development.RESULTS: BioBuilder is a Zope-based software t
The exclusive charmonium production process in pp annihilation with an associated π0 meson pp→J/ψπ0 is studied in the framework of QCD collinear factorization. The feasibility of measuring this reaction through the J/ψ→e+e- decay channel with the AntiProton ANnihilation at DArmstadt (PANDA) experiment is investigated. Simulations on signal reconstruction efficiency as well as the background reject
Let B be a locally integrable matrix function, W a matrix Ap weight with 1
The ability to flexibly plan for events outside of the current sensory scope is at the core of being human and is crucial to our everyday lives and society. Studies on apes have shaped a belief that this ability evolved within the hominid lineage. Corvids, however, have shown evidence of planning their food hoarding, although this has been suggested to reflect a specific caching adaptation rather
Summary: Brain Computer interfaces (BCIs) are stable inside the brain over long periods of time and that have minimal effects on the physiological conditions of the neural tissue. This chapter reviews the state-of-the-art of neural interfaces and the concepts behind recent research and development of biocompatible BCIs. It focuses on various tissue responses in the brain to an implanted foreign bo
One promising method to prepare protein-selective polymers is the epitope-imprinting approach, where surface-accessible peptides from a target protein are used as templates to create surface-exposed binding sites on molecularly imprinted polymers (MIPs). However, selection of a suitable peptide target is not always straightforward, and synthesis of peptide on a large scale can be costly. In this w
The limited available treatment options for patients with chronic lung diseases, such as fibrosis, lead to poor prognosis after diagnosis and short survival rates. An exciting new bioengineering approach utilizes de- and recellularization of lung tissue to potentially overcome donor organ shortage and immune reactions toward the received transplant. The goal of decellularization is to create a sca
Quantitative nuclear medicine imaging is an increasingly important frontier. In order to achieve quantitative imaging, various interactions of photons with matter have to be modeled and compensated. Although correction for photon attenuation has been addressed by including x-ray CT scans (accurate), correction for Compton scatter remains an open issue. The inclusion of scattered photons within the
Background The aim of the present study was to examine the outcomes and prognostic factors after surgery with curative intent for distal cholangiocarcinoma during a modern timespan, in a Swedish tertiary referral center. Methods All patients who underwent pancreaticoduodenectomy for distal cholangiocarcinoma between April 2008 and December 2015 were identified. Survival was estimated using the Kap
A price can be set in different ways for a manufactured component, most commonly based on estimated manufacturing costs, market intelligence, and market adopted pricing or customer value. Pricing is one of the key factors when selecting subcontractors in the manufacturing sector. As a subcontractor, there are certain risks connected with pricing of a product, too low pricing leads to losses, where
In the past decade, high throughput screening (HTS) has changed the way biochemical assays are performed, but manipulation and mechanical measurement of micro- and nanoscale systems have not benefited from this trend. Techniques using microbeads (particles approximately 0.1-10 mum) show promise for enabling high throughput mechanical measurements of microscopic systems. We demonstrate instrumentat
The tremendous development in the past ten last years of the Internet and ICT at large (whether it be in general technologies like semantic modeling, knowledge mining, RFID or mobile technologies, or domain-oriented ones like e-commerce, collaborative spaces, digital mock-ups, etc.) has opened a large spectrum of potential applica-tions of ICT in the Construction sector. The real adaptation and de
Periodic boundary conditions (PBC) are well suited to describe repetitive structures in space, yet flawed for isotropic setups in which it is commonly used. We present an approach based on exploiting the congruency of a unit cell which combines the periodic nature of PBC with isotropy of an alternating cell. By applying these isotropic periodic boundary conditions (IPBC) to the standard Ewald summ
Head turning experiments are widely used to test the cognition of both human infants and non-human animal species. Monitoring head turns allows researchers to non-invasively assess attention to acoustic or visual stimuli. In the majority of head turning experiments, the head direction analyses have been accomplished manually, which is extremely labor intensive and can be affected by subjectivity o
We have fabricated nanometer-sized interdigitated electrode patterns using electron beam lithography and liftoff techniques. The aim of the investigation was to find out whether the dimensions (i.e., the electrode separations) of the pattern would affect the admittance signal of the biomolecules in between the electrodes. Since the admittance signal scales with the geometrical factor A/d, where A
Heat supply bottlenecks are common in district heating (DH) networks and makes the DH network work in a non-optimal way, why it is beneficial to address them. The purpose of this paper is thus to investigate risks, opportunities, added values and issues coupled to various bottleneck measures. This is made by in depth interviews with DH companies and through DH network simulations. The results show
We present two new data structures for computing values of an n-variate polynomial P of degree at most d over a finite field of q elements. Assuming that d divides q- 1 , our first data structure relies on (d+ 1) n + 2 tabulated values of P to produce the value of P at any of the qn points using O(nqd2) arithmetic operations in the finite fie
