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[Context] The continuous inflow of bug reports is a considerable challenge in large development projects. Inspired by contemporary work on mining software repositories, we designed a prototype bug assignment solution based on machine learning in 2011-2016. The prototype evolved into an internal Ericsson product, TRR, in 2017-2018. TRR’s first bug assignment without human intervention happened in A
Breast cancer is the most frequently diagnosed cancer in females globally. However, we know relatively little about trends in males. This study describes United Kingdom (UK) secular trends in breast cancer from 2000 to 2021 for both sexes. We describe a population-based cohort study using UK primary care Clinical Practice Research Datalink (CPRD) GOLD and Aurum databases. There were 5,848,436 elig
Partitioned polygenic scores (pPS) have been developed to capture pathophysiologic processes underlying type 2 diabetes (T2D). We investigated the association of T2D pPS with diabetes-related traits and T2D incidence in the Diabetes Prevention Program. We generated five T2D pPS (b-cell, proinsulin, liver/lipid, obesity, lipodystrophy) in 2,647 participants randomized to intensive lifestyle, metfor
Second-order phase transitions appear as a divergence in one of the linear response functions. For a system of correlated electrons, the relevant divergent response can and does involve many-particle observables, most famously the double occupancy. Generally, evaluating the linear response function of many-particle observables requires a many-particle generalization of the Bethe-Salpeter equation.
Mutations in the CFTR gene result in impaired host defense during cystic fibrosis (CF), where Pseudomonas aeruginosa becomes a key pathogen. We investigated the expression pattern of the antibacterial growth factor midkine in CF and possible interference with its activity by the altered airway microenvironment. High midkine expression was found in CF lung tissue compared with controls, involving e
Background - Previous reports have implicated multiple genetic loci associated with AF, but the contributions of genome-wide variation to AF susceptibility have not been quantified. Methods and Results - We assessed the contribution of genome-wide single-nucleotide polymorphism variation to AF risk (single-nucleotide polymorphism heritability, h2 g) using data from 120 286 unrelated individuals of
Abstract in Undetermined Comment: Geoengineering efforts to bring oxygen into the deep Baltic should be abandoned, says Daniel J. Conley
An OH-functional polyester has been acrylated via transesterification of ethyl acrylate, catalyzed by Candida antarctica lipase B (CalB) in two different preparations: Novozym(R) 435 and immobilized on Accurel(R) MP1000. The batch process resulted in incomplete acrylation as well as severe degradation of the polyester. A high degree of acrylation was achieved by optimization through the applicatio
TURBT is the initial diagnostic procedure in bladder cancer (BC). Hypothetically, tumor resection could induce seeding of cancer cells into the circulation and subsequent metastatic disease. The objective of this study was to ascertain whether TURBT induces measurable seeding of cancer cells into the vascular system.
This paper presents the results of an explorative study on the strategies and tactics applied by the mechanical designer during the later phases of the design process. The method chosen for this study is experiment-based, which is appropriate for an in-depth examination of the designer's activities. Six experiments have been run based on three dimensions: 1) the carrying out of basic design tasks
New Information Systems Development Methodologies (ISDMs) are suggested in the belief that their deployment would be beneficial to consultants in their work. A large number of ISDMs already exist but their value has been questioned and at the same time new methodologies continue to be introduced in an attempt to support and improve the practice of information systems development work. What is not
The growing complexity of integrated circuits and increasing component density place higher requirements for raw material and clean room standards, which demand significant amounts of energy. In spite of these developments, semiconductor facilities managed to reduce their energy intensity measured per product unit. At the same time, the impact of increasing circuit integration on upstream life cyc
A method for estimation of unknown adsorption parameters in a detailed chromatography model including the Langmuir adsorption expression is proposed. The model describes the concentration of the solute in the mobile phase and considers extemal/intemal mass transfer resistance and adsorption dynamics. The external volume and its mixing effect are also considered. The unknown model parameters estima
Highly oxygenated organic molecules (HOM) play a crucial role in the formation and growth of atmospheric particles, thereby influencing air quality and climate. A comprehensive understanding of HOM formation, particularly an accurate quantification of their yields, is essential to constrain the climate and health impacts of aerosols. Previous studies often reported constant HOM yields as averages,
Conductive polymer direct electroplating technology is one of the research hotspots in printed circuit board manufacturing. In this work, we designed a simple, efficient and environmental friendly chemical polymerization method to form a conductive polymer-based metal-mixed composite film where the polymer was polythiophene and the metals included copper and silver (PT-based Cu/Ag composite film).
I Sverige finns ett antal företag som med stöd av offentlighetsprincipen samlar in personuppgifter ur allmänna handlingar och publicerar dessa i söktjänster på internet. Genom användning av söktjänsterna går det att skapa sig en utförlig bild av en viss individ. Söktjänsterna har i regel beviljats utgivningsbevis och omfattas därför av grundlagsskyddet i YGL. I Sverige har en vedertagen uppfattninIn Sweden, there are several companies that, relying on the principle of public access to official documents, gather personal data and publish this information in online search services. Through use of these services, it is possible to access a detailed profile of a specific individual. The search services have generally been granted a so-called certificate of publication and are consequently prot
Traditional mechanical methods for the recycling of polyethylene terephthalate (PET) fail to produce high-quality materials suitable for upcycling. Alternatives like chemical recycling face challenges due to the high energy demands, concerns, and the cost of specialized equipment. Enzymatic recycling has emerged as a promising alternative, offering a simple process under environmentally friendly c
Elite athletes in entrepreneurship is an emergent field of research with scholars showing advantageous entrepreneurial traits in the athletes and a good job-fit between athletes and entrepreneurship. However, current literature presents a fragmented view, often examining characteristics in isolation, and failing to show the process of how elite athletes become entrepreneurs. Hence, this study seek
Non-linear transceivers and non-reciprocity of downlink and uplink channels are two major challenges in the deployment of massive multiple-input-multiple-output (MIMO) systems. We consider an over-the-air (OTA) approach for digital pre-distortion (DPD) and reciprocity calibration to jointly address these issues. In particular, we consider a memory-less non-linearity model for the base station (BS)
