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Optimized adeno-associated viral vector-mediated striatal DOPA delivery restores sensorimotor function and prevents dyskinesias in a model of advanced Parkinson's disease.

Viral vector-mediated gene transfer utilizing adeno-associated viral vectors has recently entered clinical testing as a novel tool for delivery of therapeutic agents to the brain. Clinical trials in Parkinson's disease using adeno-associated viral vector-based gene therapy have shown the safety of the approach. Further efforts in this area will show if gene-based approaches can rival the therapeut

Seven elements for capacity development for disaster risk reduction

Capacity development for disaster risk reduction is an important process to substantially reduce disaster losses, which threaten sustainable development and the achievement of the Millennium Development Goals. This paper presents a theoretical framework with seven elements for capacity development for disaster risk reduction that has been tested in practise with noteworthy results. The seven eleme

Coherent Bragg imaging of 60 nm Au nanoparticles under electrochemical control at the NanoMAX beamline

Nanoparticles are essential electrocatalysts in chemical production, water treatment and energy conversion, but engineering efficient and specific catalysts requires understanding complex structure-reactivity relations. Recent experiments have shown that Bragg coherent diffraction imaging might be a powerful tool in this regard. The technique provides three-dimensional lattice strain fields from w

Intraductal papillary mucinous neoplasms of the pancreas – a cost-effectiveness analysis of management strategies for the branch-duct subtype

Background: Branch-duct intraductal papillary mucinous neoplasm (BD-IPMN) presents a clinical conundrum. Rigorous long-term surveillance or surgical resection is recommended. The economic consequences of the management have not been fully investigated. Methods: A Markov decision model compared 4 strategies for low-risk BD-IPMN: I = upfront total pancreatectomy, II = upfront partial pancreatectomy,

Identification and citation of digital research resources

Environmental research infrastructures are often built on a large number of distributed observational or experimental sites, run by hundreds of scientists and technicians, financially supported and administrated by a large number of institutions. It becomes very important to acknowledge the data sources and their providers. There is also a strong need for common data citation tracking systems that

Myoepithelium assessment with p63 immunostaining in formalinfixed paraffin-embedded breast cancer tissue pre-treated with RNA-later

Objective: To assessmyoepithelium with p63 in fresh breast cancer (BC)tissue samples collected in RNA later for further analysis with NextGeneration Sequencing (NGS) technique. For a better understanding ofthe NGS bulk-analysis, a central part of the sample in RNA-later isformalin-fixed paraffin-embedded to score relative cellularity in % onhematoxylin-eosin (HE) staining (% of invasive cancer, ca

Quality of up to 35 years old archival breast cancer tissue in paraffinblocks for estrogen receptor evaluation

Objective: Estrogen receptor (ER) positive breast cancer (BC) can havean insidious course with disease-relapse decades after primary surgery.New analysis performed on archived formalin-fixed paraffin-embedded(FFPE) tissue are important for disease-management in late BC-relapseand an important tool in BC-research. However, although loss of immunoreactivityin tissue slides after sectioning has been

Carbonaceous aerosol source apportionment using the Aethalometer model -evaluation by radiocarbon and levoglucosan analysis at a rural background site in southern Sweden

With the present demand on fast and inexpensive aerosol source apportionment methods, the Aethalometer model was evaluated for a full seasonal cycle (June 2014–June 2015) at a rural atmospheric measurement station in southern Sweden by using radiocarbon and levoglucosan measurements. By utilizing differences in absorption of UV and IR, the Aethalometer model apportions carbon mass into wood burnin

Real utopias and dystopias from the Colombian Amazon : collective future scenarios under government & FARC-EP post-agreement period

After more than 50 years of internal armed conflict, the peace agreement between the Colombian Government and the Revolutionary Armed Forces of Colombia- People’s Army (FARC-EP) raises both hope and concern. There are several opportunities for people, derived from wealth and land redistribution. However, the environmental sustainability of the mechanisms to implement the agreements represent the b

Balansgång mellan kontradiktion och inkvisition - En studie om den svenska brottmålsprocessens förenlighet med rätten till rättvis rättegång

Den svenska brottmålsprocessen är i grunden kontradiktorisk, men har inkvi-sitoriska inslag. Exempelvis är rätten, enligt 30 kap. 3 § rättegångsbalken, inte bunden av de angivna bestämmelserna i åklagarens stämningsansökan. Det är i stället rättens ansvar att, i enlighet med officialprincipen, bestämma den rättsliga innebörden av gärningsbeskrivningen. År 1995 inkorporerade Sverige EuropakonventioThe Swedish criminal procedural system is fundamentally based on the ad-versarial principle, but it also includes inquisitorial elements. For instance, according to Chapter 30, Section 3 of the Code of Judicial Procedure, the court is not bound by the specified legal provisions in the prosecutor's writ-ten indictment. Instead, it is the responsibility of the court, in accordance with the offic

Begreppet rättssäkerhet och betydelsen av begreppet i den offentliga debatten om anonyma vittnen

Frågan om anonyma vittnen har länge varit föremål för debatt i den juridiska världen. Är det en rättssäker åtgärd att införa ett system med anonyma vittnen? Hur skulle ett sådant system, om det infördes, överensstämma med de rättssäkerhetsgarantier som tillstår den tilltalade i rättsprocessen? Tidigare forskning kring anonyma vittnen har fokuserat på rättssäkerheten och försökt nå en slutsats krinThe issue on anonymous witnesses has in Sweden been frequently discus-sed in the legal debate over the years. Is it according to the rule of law to impose such a system? How does a system of anonymous witnesses con-form with the principles of the rule of law given to the accused during a hearing? Past research has centered the discussion around the rule of law and the effects an imposition of a sy

Omedelbarhetsprincipen - Ett hinder mot en effektiv brottmålsprocess eller en nödvändighet för upprätthållandet av rättssäkerheten?

Den rådande rättspolitiska debatten avseende omedelbarhetsprincipen och dess behov av reform har lett till ett flertal offentliga utredningar och propositioner. Dessa förslag har under uppsatsskrivandets gång resulterat i lagändringar medförande att tidiga förhör får åberopas som bevis i domstol. Syftet med denna framställning är att med avstamp i förarbetena till 1948 års rättegångsbalk göra en jThe current legal policy debate regarding the principle of immediacy and its needs for reform has led to several Swedish Government Official Reports and government bills. During the writing of this essay, these proposals have resulted in amendment of an act; early non-public hearings may now be plead as evidence in court. The purpose of this thesis is to make a comparison between corresponding arg

Addressing Failures in Robotics Using Vision-Based Language Models (VLMs) and Behavior Trees (BT)

In this paper, we propose an approach that combines Vision Language Models (VLMs) and Behavior Trees (BTs) to address failures in robotics. Current robotic systems can handle known failures with pre-existing recovery strategies, but they are often ill-equipped to manage unknown failures or anomalies. We introduce VLMs as a monitoring tool to detect and identify failures during task execution. Addi

Synthetic versus real : an analysis of critical scenarios for autonomous vehicle testing

With the emergence of autonomous vehicles comes the requirement of adequate and rigorous testing, particularly in critical scenarios that are both challenging and potentially hazardous. Generating synthetic simulation-based critical scenarios for testing autonomous vehicles has therefore received considerable interest, yet it is unclear how such scenarios relate to the actual crash or near-crash s

AI Act high-risk AI compliance challenge and industry impact : a multiple case study

The AI Act marks a new chapter in AI governance, affecting companies around the world seeking to offer their services within the European Union. This study focuses on the comprehensive AI Act requirements set out for high-risk AI systems. We explored the perceived compliance challenge for the AI Act's high-risk requirements and associated contributing factors; the AI Act's impact on industry in te

Dalby Söderskog : en studie av trädarternas sammansättning 1921 jämfört med 2005

Dalby Söderskog är belägen tio kilometer öster om Lund och har varit nationalpark sedan 1918. Växtligheten består av ädellövträd samt en rik vårflora av bland annat vitoch gulsippor och skånsk nunneört. Sommaren 1921 utfördes en taxering av skogen och en karta upprättades (figur 1). Kartan visar Söderskogens utbredning samt varje träd i densamma. Arbetet grundar sig på just denna karta men tar äveThe national park Dalby Söderskog is situated ten kilometres east of Lund and has been a national park since 1918. The vegetation consists of a deciduous forest of Oak, Beech, Elm, Ash and Alden. The forest is also famous thanks to its rich spring flora of among others Anemóne nemorósa, Anemóne ranunculoídes and Corýdalis bulbosa. In the summer of 1921 a map was drawn that shows the distribution o

Work plan 2019

The Centre for East and South- East Asian Studies Work Plan 2019 LUND UNIVERSITY | CENTRE FOR EAST AND SOUTH-EAST ASIAN STUDIES 2 CENTRE FOR EAST AND SOUTH-EAST ASIAN STUDIES WORK PLAN • 2019 2019 Work Plan for the Centre for East and South-East Asian Studies GENERAL INTRODUCTION Since 1 January 2019, the Centre belongs to the Joint Faculties of Humanities and Theology where it is a section at the

https://www.ace.lu.se/sites/ace.lu.se/files/work_plan_2019.pdf - 2026-05-23

Vt14-kl-ksma44

LL_KSMA44_131204 Litteraturlista för Retail management - plats- och affärsrelationer, (KSMA44) 15 hp Litteraturlistan är fastställd av styrelsen för institutionen för service management 2011-1027, senast reviderad av styrelsen för institutionen för service management och tjänstevetenskap 2013-12-04 (enbart uppdaterad information om var litteraturen finns). Litteraturlistan börjar gälla den 2014-01

https://www.ses.lu.se/sites/ses.lu.se/files/vt14-kl-ksma44.pdf - 2026-05-23