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BACKGROUND: Previous studies showed higher early mortality rates among patients treated with antiretroviral drugs in settings with limited resources. One of the reasons was late presentation of patients to care. With improved access to HIV services, we expect improvements in disease stage at presentation. Our objective was to assess the effect of improved availability of HIV services on patient pr

Introduction: The aim of the study is to compare the effect of cervical length measured with transvaginal ultrasound in the second trimester on the risk of spontaneous preterm delivery (PTD) between different risk groups of asymptomatic women with a singleton pregnancy. Material and methods: This is a pre-planned exploratory analysis of the CERVIX study, a prospective blinded multicenter diagnosti

Forest composition characteristic of the Mid-Holocene has survived on Hallands Väderö, an island nature reserve off the south west coast of Sweden. Current veteran Tilia and Quercus trees contribute to a remarkably rich biodiversity of fungi, bryophytes, lichens and insects. Understanding which potential factors influence Holocene vegetation dynamics can support efforts to protect biodiversity, bu

Background: Avoidable mortality is considered as a potential indicator of the influences of public health policies and healthcare quality on population health. This study aimed to examine the trend in avoidable mortality and its influence on rising life expectancy (LE) and declining gender gap in LE (GGLE) in Sweden. Methods: We extracted data on causes of death by age, sex, and year from nationa

Neurofilament light (NfL) is a marker of neuroaxonal injury, a prominent feature of Alzheimer's disease. It remains uncertain, however, how it relates to amyloid and tau pathology or neurodegeneration across the Alzheimer's disease continuum. The aim of this study was to investigate how plasma NfL relates to amyloid and tau PET and MRI measures of brain atrophy in participants with and without cog

Aim: The first Swedish National Guidelines for Ovarian Cancer (NGOC) were published in 2012. We aimed to evaluate surgical outcomes and survival in patients with stage IIIC-IV disease, before and after the NGOC implementation. Method: Women with primary epithelial ovarian cancer, FIGO stage IIIC–IV, registered in the Swedish Quality Registry for Gynecologic Cancer 2008–2011 and 2013–2016 were incl

The dynamics of blue and green water partitioning under vegetation and climate change, as well as their different interactions during wet and dry periods, are poorly understood in the literature. We analyzed the impact of vegetation changes on blue water generation in a central Spanish Pyrenees basin undergoing intense afforestation. We found that vegetation change is a key driver of large decreas

Spatial variation in community composition may be driven by a variety of processes, including environmental filtering and dispersal limitation. While work has been conducted on the relative importance of these processes on various taxa and at varying resolutions, tests using high-resolution empirical data across large spatial extents are sparse. Here, we use a dataset on the presence/absence of br

Vegetation phenology obtained from time series of remote sensing data is relevant for a range of ecological applications. The freely available Sentinel-2 imagery at a 10 m spatial resolution with a ~ 5-day repeat cycle provides an opportunity to map vegetation phenology at an unprecedented fine spatial scale. To facilitate the production of a Europe-wide Copernicus Land Monitoring Sentinel-2 based

Both the East Asian winter monsoon (EAWM) and El Niño (EN) activities are vital climate modes that regulate the Pacific hydrologic cycle. However, the Holocene interactions among the EAWM, EN activities, and tropical Pacific precipitation remain unclear due to the lack of appropriate EAWM proxies. Here, we present high-resolution grain size records from the East China Sea shelf along with a transi

Climate warming leads to vast changes in the land cover types and plant biomass in the northern high-latitude regions. The overall trend is of shrubland and tree lines moving northwards, while changes in different land cover types and vegetation growth in response to climate change are largely unknown. Here, we selected land areas with latitudes higher than 50°N as the study area. We compared the

Warmer or cooler spring in northern high latitudes will, for the most part, directly impact gross primary productivity (GPP) of ecosystems, but also carry consequences for the upcoming seasonal GPP. Spatiotemporal patterns of these legacy effects are still largely unknown but important for improving our understanding of how plant phenology is associated with vegetation dynamics. In this study, imp

Background: The complexity of pancreaticoduodenectomy and fear of morbidity, particularly postoperative pancreatic fistula, can be a barrier to surgical trainees gaining operative experience. This meta-analysis sought to compare the postoperative pancreatic fistula rate after pancreatoenteric anastomosis by trainees or established surgeons. Methods: A systematic review of the literature was perfor

An improved understanding of past interactions between terrestrial vegetation and various forcings, such as climate change, human impact, and paleofire, is crucial for assessing impacts of future global change on terrestrial ecosystems. This study seeks to find the key factor or factors that have driven Holocene vegetation change along the East Asian monsoon margin. Several high-resolution pollen

Arctic observing and data systems have been widely recognized as critical infrastructures to support decision making and understanding across sectors in the Arctic and globally. Yet due to broad and persistent issues related to coordination, deployment infrastructure and technology gaps, the Arctic remains among the most poorly observed regions on the planet from the standpoint of conventional obs

Cold region ecosystems store vast amounts of soil organic carbon (C), which upon warming and decomposition can affect the C balance and potentially change these ecosystems from C sinks to carbon dioxide (CO2) sources. We quantified the decadal year-round CO2 flux from an alpine steppe-ecosystem on the Tibetan Plateau using eddy covariance and automatic chamber approaches during a period of signifi

Water demand growth coupled with its high spatial-temporal mismatch of water resources will lead to an increasing water scarcity worldwide. In order to investigate a robust long-term water stress for ecosystems and regions across China, the improved maximum entropy production (MEP) method was utilized to obtain a reliable evapotranspiration (ET) product during 1982–2015. Afterwards four water stre

Future Arctic tundra primary productivity and vegetation community composition will partly be determined by nitrogen (N) availability in a warmer climate. N mineralization rates are predicted to increase in both winter and summer, but because N demand and –mobility varies across seasons, the fate of mineralized N remains uncertain. N mineralized in winter is released in a “pulse” upon snowmelt and