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Early Holocene vegetation development at Mesolithic fen dwelling sites in Dagsmosse, south-central Sweden, and its implications for understanding environment–human dynamics at various scales

Recent discoveries of several Mesolithic sites within the Dagsmosse Basin, south-central Sweden, offer an opportunity to study the lifestyle and skillsets of Mesolithic hunter-gatherer-fishers operating in wetland environments. In this paper, we present a combined archaeological and palaeoecological analysis of a Mesolithic fenland environment using Repetitive-Proxy Pollen Analysis (RPPA) of early

The influence of external forcing on subdecadal variability of regional surface temperature in CMIP5 simulations of the last millennium

We use Granger causality to investigate the influences of external forcings on subdecadal variability of regional near-surface air temperature (SAT) in past millennium simulations (period 850–1850 A.D.) of the Coupled Model Intercomparison Project Phase 5 (CMIP5) models. Our results strengthen the conclusion for robust influence of volcanic forcing on SAT during preindustrial times of the last mil

Changes in joint cartilage aggrecan after knee injury and in osteoarthritis

Objective. To determine the concentrations of aggrecan fragments in synovial fluid from patients with knee joint injury, osteoarthritis (OA), or acute pyrophosphate arthritis (PPA; pseudogout), and to test their relative reactivity with the 846 epitope, a putative marker of cartilage aggrecan synthesis. Methods. Samples of knee joint fluid from 385 patients and 9 healthy-knee volunteers were obtai

Business Process and Business Rules Modelling In Concert for e-Service Design and Business Alignment

Business Rules (BR) and Business Processes (BP) are essential pillars in any Business Information System (BIS) and important areas of BIS design (BISD). Historically, BRs have been overlooked as a part of BISD. The Business Rules Approach (BRA) focuses on concepts and methods to remedy the neglected BR design and management. BRs in this perspective are stateless and concerned with the “what” of a

Dynamic modeling of urban hydrology in a geographic information system-setting with TFM-DYN

The TFM-DYN model represents a significant advancement from static flow accumulation estimations into dynamic hydrological modeling (Nilsson et al., 2021). It incorporates variable precipitation in time and space as input together with high-resolution topography and includes functions for friction and infiltration to produce results such as water depths, flow velocity, inundated areas, flow pathwa

Examining cultural background and the protective effect of marriage on alcohol use disorder in Sweden

Background: Little is known about whether the protective effect of marriage on alcohol use disorder (AUD) varies by cultural background. Aims: Using Swedish national data, we examined whether marriage is associated with a stronger reduction in AUD risk among Swedes of a Swedish background (i.e. those with two Swedish-born parents) compared to Swedes with a foreign background (i.e. one or two forei

Noisy One-Point Homographies are Surprisingly Good

Two-view homography estimation is a classic and fundamental problem in computer vision. While conceptually simple, the problem quickly becomes challenging when multiple planes are visible in the image pair. Even with correct matches, each individual plane (homography) might have a very low number of inliers when comparing to the set of all correspondences. In practice, this requires a large number

A systematic review and synthesis of 489 studies investigating treatments for negative symptoms in the schizophrenia spectrum : Trial designs, demographics and clinical characteristics

Negative symptoms in schizophrenia spectrum are associated with minimal treatment responses. The search for effective treatments is potentially hampered by heterogenous study-designs and sample characteristics depending on the intervention category. This PRISMA-compliant systematic review/synthesis aims to describe the literature on negative symptoms interventions for schizophrenia spectrum disord

TOI-5108 b and TOI 5786 b : Two transiting sub-Saturns detected and characterized with TESS, MaHPS, and SOPHIE

We report the discovery and characterization of two sub-Saturns from the Transiting Exoplanet Survey Satellite (TESS) using high- resolution spectroscopic observations from the MaHPS spectrograph at the Wendelstein Observatory and the SOPHIE spectrograph at the Haute-Provence Observatory. Combining photometry from TESS, KeplerCam, LCOGT, and MuSCAT2, along with the radial velocity measurements fro

Flow inefficiencies in non-obstructive HCM revealed by kinetic energy and hemodynamic forces on 4D-flow CMR

Patients with non-obstructive hypertrophic cardiomyopathy (HCM) exhibit myocardial changes which may cause flow inefficiencies not detectable on echocardiogram. We investigated whether left ventricular (LV) kinetic energy (KE) and hemodynamic forces (HDF) on 4D-flow cardiovascular magnetic resonance (CMR) can provide more sensitive measures of flow in non-obstructive HCM.Methods and resultsNinety

Inter-rater variability for the American Society of Anesthesiologists classification in patients undergoing hepato-pancreato-biliary surgery (MILESTONE-2) : international survey among surgeons and anaesthesiologists

BACKGROUND: Patients undergoing hepato-pancreato-biliary surgery are typically preoperatively assessed using the American Society of Anesthesiologists (ASA) classification, which is also used for case-mix adjustment when comparing centre outcomes. Studies determining the inter-rater variability of the ASA classification within hepato-pancreato-biliary surgery are currently lacking.METHODS: An inte

Cangrelor During Percutaneous Coronary Intervention in Patients With Cardiogenic Shock or Cardiac Arrest

Background: Little is known regarding treatment with cangrelor during percutaneous coronary intervention (PCI) in patients with myocardial infarction complicated by cardiogenic shock or cardiac arrest. Objectives: The aim of this study was to investigate the effects of such cangrelor treatment during PCI in patients with myocardial infarction complicated by cardiogenic shock or cardiac arrest. Met

Cardiac rehabilitation and physical activity decrease the risk of stroke after acute myocardial infarction : A nationwide cohort study in Sweden

Background: Stroke and acute myocardial infarction (AMI) rank among the leading causes of mortality. Physical activity and exercise are recommended as part of rehabilitation after AMI to prevent cardiovascular events, but the importance for stroke prevention has not been investigated using population-based data. Objectives: To determine associations between participation in exercise-based cardiac

Platelet transfusion practice in the intensive care unit : the Nine-I international platelet transfusion survey

BACKGROUND: Platelet transfusions are frequent in the Intensive Care Unit (ICU), either as prophylaxis against bleeding complications or as treatment for bleeding. The European Society of Intensive Care Medicine guidelines for ICU patients generally recommend not using prophylactic platelet transfusions unless the platelet count falls below 10 × 10 9 cells/L in non-bleeding patients and make no re

Management of acute mesenteric ischaemia in adult patients : a systematic review and meta-analysis

Background: Guidance on managing acute mesenteric ischaemia (AMI) is largely based on expert opinion and retrospective studies pooling different subtypes of AMI. In clinical practice, management strategy is often selected based on the patient’s severity of illness, whereas randomized controlled trials or even adjusted analyses comparing different strategies are rarely available. We aimed to perfor

Bimodal solutions in peritoneal dialysis : what can we expect from different glucose volumes added to the icodextrin bag? Data from a simulation procedure

Background: Ultrafiltration (UF) insufficiency in peritoneal dialysis (PD) often leads to transfer to hemodialysis. Therefore, strategies to prolong time on therapy are needed. The use of a combined crystalloid and colloid solution, also called bimodal PD, can help improve UF. Methods: We propose a method for reconstituting bimodal solutions. Three bimodal PD solutions, with respectively 100 ml (s