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To give the latest novel by Joyce Carol Oates a book binding design identical with one used for a novel by for instance Orhan Pamuk would be unthinkable in today’s book market. What I like to call the title specific book binding, or book cover – that is a binding or cover designed for a specific title – is something we take for granted to such an extent that we hardly even reflect over the phenome

This commentary describes a program developed to help reduce the incidence of anterior cruciate ligament injuries in soccer players. The basic principles underlying the injury prevention protocol are described with respect to the proprioceptive control mechanisms at the knee joint. This is followed by a detailed description of the program.

The ongoing climate change can modulate the behavior of global vegetation and influence the terrestrial biosphere carbon sink. Past observation-based studies have mainly focused on the linear trend or interannual variability of the vegetation greenness, but could not explicitly deal with the effect of natural decadal variability due to the short length of observations. Here we put the variabilitie

Continuous evaluation of model results against observational data isvital to improving model projections of the structure and function offorest ecosystems. In this poster, we evaluate the forest management module of LPJ-GUESS (ver. 4. 1.2, rev 11016) across a latitudinal gradient in Sweden. The poster was presented at the LPJ-GUESS Community Meeting in Lund, May 3rd, 2023.

Process-based land surface models are important tools for estimating global wetland methane (CH4) emissions and projecting their behavior across space and time. So far there are no performance assessments of model responses to drivers at multiple time scales. In this study, we apply wavelet analysis to identify the dominant time scales contributing to model uncertainty in the frequency domain. We

Aim: Earth observation-based estimates of land–atmosphere exchange of carbon are essential for understanding the response of the terrestrial biosphere to climatic change and other anthropogenic forcing. Temperature, soil water content and gross primary production are the main drivers of ecosystem respiration (Reco), and the main aims of this study are to develop an Reco model driven by long-term g

The aim of the present study was to gain information about adrenergic-, cholinergic- and nonadrenergic, non-cholinergic (NANC)- transmitter systems/mediators in the rat vagina, and to characterize its smooth muscles functionally. Tissue sections from vagina of Sprague Dawley rats were immunolabelled with antibodies against protein gene product 9.5 (PGP), synaptophysin (Syn), tyrosine hydroxylase (

Caveolae are 50-100nm large membrane invaginations that play a role in cellular signaling. The aim of the present study was to assess whether muscarinic M(3) receptors and the K(ATP) channel subunit Kir6.1 are associated with human detrusor caveolae, and to pharmacologically assess the relevance of this organization for contractility. Detrusor strips were dissected and used in ultrastructural, bio

The roles of intracellular Ca2+ stores and ryanodine (Ry) receptors for vascular Ca2+ homeostasis and viability were investigated in rat tail arterial segments kept in organ culture with Ry (10 100 M) for up to 4 days. Acute exposure to Ry or the non-deactivating ryanodine analogue C10-Oeq glycyl ryanodine (10 M) eliminated Ca2+ release responses to caffeine (20 mM) and noradrenaline (NA, 10 M), w

1 Non-adrenergic, non-cholinergic (NANC) relaxations induced by electrical field stimulation (EFS)were studied in pig isolated urethra. The mechanism for relaxation was characterized by measurement of cyclic nucleotides and by study of involvement of different subsets of voltage-operated calcium channels (VOCCs). 2 EFS evoked frequency-dependent and tetrodotoxin-sensitive relaxations in the prese

IntroductionSports‐related injuries and illnesses in Paralympic sport (SRIIPS) is a concern, but knowledge about the aetiology and risk factors is limited. The aim of this study was to describe the annual incidence, type and severity of injuries and illnesses among Swedish Paralympic athletes and to assess risk factors.MethodsSwedish Paralympic athletes (n=107) self‐reported SRIIPS every week duri

Wood density is a crucial anatomical trait influencing forest carbon storage. However, dynamic global vegetation models (DGVMs) typically assume a fixed species-level wood density, neglecting environment-driven variability. In this proof-of-concept study, we explore the potential impact of dynamic wood density on tree- and forest-level carbon storage by integrating a simple temperature-response fu

Urbanization has resulted in a gigantism of urban complexes and in many environmental and social problems. The situation on the surface and the principles of sustainable development compel urban planners to utilize the urban underground space, which for centuries has been almost exclusively the application field of mining. More often than not spatial planning in urban areas allocates various land-

Reconstructions and simulations disagree on whether the Holocene exhibited a long-term cooling or warming signal. Anthropogenic land-use could be an important forcing regionally, but available population-based estimates differ widely. We examine transient Holocene climate model simulations forced with three population-based disturbed-land reconstructions and compare this with a fourth scenario der

Muscular deficits and functional limitations have been found years after meniscectomy of the knee. The purpose of this randomized controlled trial was to examine the effect of functional exercise training on functional performance and isokinetic thigh muscle strength in middle-aged patients subsequent to meniscectomy for a degenerative tear. Four years after meniscectomy, 45 patients (29 men, 16 w