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Autoantibodies to the islet cell 65-kilodalton isoform of glutamic acid decarboxylase (GAD65) are present in most patients with type 1 diabetes mellitus years before the clinical manifestation of the disease. GAD65 autoantibodies are also present in a subset of patients with type 2 diabetes who frequently become insulin dependent. In the present study, we evaluated a new, commercially available ra

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To meet the United Nations Sustainable Development Goals (SDG) on sustainable production and consumption (goal 12), the construction sector should be considered a key area to improve efficient use of natural resources (goal 12.2) and reduce waste generation (goal 12.5). With buildings being more energy efficient during their use phase, the relative importance of embodied energy and natural resourc

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Objectives: Irreversible electroporation (IRE) is a new modality for tumor ablation. Electrodes are placed around the tumor, and a pulsed, direct current with a field strength of 2000 V/cm is delivered. The direct current drives cells into apoptosis and cell death without causing significant heating of the tissues, which spares the extracellular matrix and proteins. The purpose of this review was

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Introduction: The importance of mobile health has increased during recent years but few studies have described the use of apps among persons with neurological disabilities. Aim: The aim of this paper was to describe how persons ageing with a neurological disability experience barriers and facilitators in relation to using apps in everyday life. Method: A qualitative approach was used. 16 persons w

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Objective To evaluate the effectiveness of oral glucosamine in subgroups of people with hip or knee osteoarthritis (OA) based on baseline pain severity, body mass index (BMI), sex, structural abnormalities and presence of inflammation using individual patient data. Methods After a systematic search of the literature and clinical trial registries, all randomised controlled trials (RCTs) evaluating

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Geocoding longitudinal and individual-level historical demographic databases enables novel analyses of how micro-level geographic factors affected demographic outcomes over long periods. However, such detailed geocoding involves high costs. Additionally, the high spatial resolution cannot be properly utilized if inappropriate methods are used to quantify the geographic factors. We assess how diffe

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Horseflies (Tabanidae) are polarotactic, being attracted to linearly polarized light when searching for water or host animals. Although it is well known that horseflies prefer sunlit dark and strongly polarizing hosts, the reason for this preference is unknown. According to our hypothesis, horseflies use their polarization sensitivity to look for targets with higher degrees of polarization in thei

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A dose survey of positron emission tomography (PET) examinations was performed in 12 regions of the Russian Federation, where the effective dose values were assessed for the various types of PET examinations. The comparison to similar published data show that the patient doses in Russia are higher than in other countries. Low-dose CT protocols and justification of multiphase CT protocols should be

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Background: The aim of this study was to investigate graft preservation, major bleeding, and reinfection rate using negative pressure wound therapy (NPWT) for perivascular surgical site infections (SSIs) in the groin after vascular surgery and factors associated with failure of treatment. Methods: Retrospective data were collected during 2004-2015. Failure of wound treatment was defined as a wound

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This thesis examines whether the general principle of the right to good, as enshrined in Article 41 of the Charter of Fundamental Rights of the European Union (CFR), can be considered an independent justiciable right for individuals. The analysis focuses in particular on recent concerns about rule of law backsliding in certain Member States and the resulting limitations on effective judicial prote

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Some numerical methods approximate the Jacobian using finite differences as part of their process. The finite difference method of approximation resembles the limit definition of the derivative. Since a computer cannot handle the mathematical concept of limits, a sufficiently small number has to be chosen as an increment. However, when the increments are chosen outside of certain acceptable ranges

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Electromagnetic compatibility (EMC) is a vital part of product development, and understanding the sources and causes of the emissions can facilitate tremendously in reaching compliance requirements and reduce the work needed for troubleshooting. At Axis Communications, where this thesis has taken place, the knowledge of EMC is an important part of their work and they aspire to improve further. Thi

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Concerto for Double Bass and Orchestra by Eduard Tubin is considered to be one of the most challenging pieces of the double bass repertoire as it is known to be a physically demanding work. It was written for double bass player Ludvig Juht who was a physically big built man and welcomed the technical challenges. This thesis aims to analyze these challenges of the piece for a player with smaller ph

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Voluntary Carbon Markets (VCM) have emerged with the intention of supporting decarbonisation and carbon dioxide removal solutions around the world. However, and despite a rapid growth, the motivations and preferences of the demand side to engage in with the VCM have not been thoroughly studied before. Iceland, the focus of this thesis, exemplifies this trend. To address this knowledge gap, this th

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With his notion of original affirmation, Paul Ricoeur wishes to reinstate the primacy of being over nothingness, joy over anguish, and affirmation over negation. Having adopted the term from Jean Nabert, he draws from the tradition of French reflective philosophy to formulate his conception of the originally affirmative nature of existence. Ricoeur argues that positive values can be found in and t

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This study aims to identify the most cost-effective and environmentally friendly retrofit solutions for enhancing the energy efficiency of second homes in Sweden. Second homes, often used intermittently throughout the year, represent a significant portion of residential energy use and carbon emissions. Therefore, optimizing energy consumption in these homes is critical for achieving national and g

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Electric cars are by many considered a sustainable solution to the ever-growing demand for road vehicles and fuel. The transportation sector is responsible for almost a third of the total greenhouse gas emissions globally and approximately 80% of these emissions can be attributed to road vehicles. Thus, there is an urgent need for a shift away from fossil fuels in the sector. While the consumer in

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This thesis evaluates the effect of Chinese Foreign direct investment (FDI) on exports and imports for the five African countries: Angola, Nigeria, South Africa, Zambia and Zimbabwe using the gravitational model. The gravitational model will analyze how both inward FDI investments and Chinese investments impact import and export by using a sample of 166 partner countries over the period 2003-2012.