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The tissue distribution and prognostic relevance of subtype-specific proteins (ASCL1, NEUROD1, POU2F3, YAP1) present an evolving area of research in small-cell lung cancer (SCLC). The expression of subtype-specific transcription factors and P53 and RB1 proteins were measured by immunohistochemistry (IHC) in 386 surgically resected SCLC samples. Correlations between subtype-specific proteins and in
BACKGROUND: Endolichenic fungi are microbes that inhabit the thalli of lichens and produce various unique chemicals that can be used for pharmaceutical purposes.PURPOSE: This study screened a library of endolichenic fungal extracts to identify novel anticancer agents capable of suppressing the tumorigenicity of human cancer cells.METHODS: Active compounds were isolated from extracts of endolicheni
Background: The aim of this study was to systematically review the literature and to perform meta-analyses on full-field electroretinography (ffERG) between healthy controls and age-related macular degeneration (AMD) to map the extent of retinal dysfunction. Summary: We systematically searched 11 databases on 3 March 2021. Eligible studies had to measure retinal function using ffERG in eyes with A
The period after birth, when an infant is initially exposed to vast amounts of environmental and microbial antigens, sets the stage for proper immune system development ensuing lifelong immunity. Simultaneous to this first-time exposure, the nursing mother provides immune protection via antibodies in the breast milk. Secretory Immunoglobulin A, as provided by the mother or produced intrinsically i
PowerPoint-presentation Introduktionsmöte ALF ST/YF 2026 – 2029 15:e oktober 2025 Niklas Nielsen, Vicedekan Malin Malmsjö, Prioriteringskommitténs ordförande ALF ST & YF Carla Vercesi, Enhetschef Forskningsekonomi Region Skåne Karin Frankel, Fakultetsekonom Lunds universitet ALF • ALF står för Avtal om Läkarutbildning och Forskning • Avtal mellan svenska staten och vissa regioner om samarbete om g
2026-02-19 1 Redovisning av miljöledningsarbetet 2025 Enligt förordning (2009:907) om miljöledning i statliga myndigheter Lunds universitet Del 1. Miljöledningssystemet Basfakta Antal årsarbetskrafter: 7 362 åa Antal kvadratmeter: 470 838 m² Miljöcertifiering, miljöpolicy och miljöutredning 1. Är myndigheten miljöcertifierad? Nej 2. Hur lyder myndighetens miljöpolicy? Lunds universitets policy för
BACKGROUND: Previous post hoc analyses of clinical trials have suggested that a higher percentage of systolic blood pressure time in target range (SBP-TTR) was associated with a decreased risk of cardiovascular disease (CVD). However, there is limited evidence from large prospective cohort studies on the relationship between long-term SBP-TTR and the risk of CVD.OBJECTIVES: The purpose of this stu
INTRODUCTION: Low birth weight is an important measure of the health of pregnant women and newborns. We investigated the prevalence of low birth weights in India over nearly three decades to assess trends and convergence across states.METHODS: Data came from five waves of the National Family Health Survey (1992-93 to 2019-21). The prevalence of low birth weight was estimated. To explore the sensit
Background In congenital aortic stenosis (CAS), commissurotomy is an option in patients not suitable to receive a valve prosthesis. However, there is often a need for future additional interventions on the aortic valve. The fate of the aortic valve is, however, essentially unknown. This study reports the need for reinterventions after surgical commissurotomy, based on a national register. Material
Background: There are currently no molecular tests to identify individual breast cancers where radiotherapy (RT) offers no benefit. Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) is a 16-gene molecular signature developed to identify low-risk cancers where RT will not further reduce recurrence rates. Methods: An individual participant data meta-analysis was performed in 623 patien
BACKGROUND: Despite the significant personal and societal burden of tic disorders (TDs), treatment outcomes remain modest, necessitating a deeper understanding of their etiology. Family history is the biggest known risk factor, and identifying risk genes could accelerate progress in the field.METHODS: Expanding upon previous sample size limitations, we added 4800 new TD cases and 971,560 controls
BACKGROUND: The first 35 years of pediatric heart transplantation (pHTx) in Sweden were investigated to determine outcomes following listing and transplantation, investigate sub-populations of recipients, and describe the presence of donor-specific antibodies (DSA) in a contemporary cohort.METHODS: Swedish children < 18 years, listed from 1/1/1989 to 31/12/2023, were included. The cohort was split
PURPOSE: To assess the risk of self-fulfilling prophecy from withdrawal of life-sustaining therapy (WLST) in comatose cardiac arrest patients undergoing neuroprognostication.METHODS: Post-hoc multicentre study matching adults resuscitated from out-of-hospital cardiac arrests, in WLST-permitting cohorts (TTM and TTM2), and non-WLST-permitting cohorts (KORHN and ProNeCA). We matched patients in a 1:
Background: Racial differences in metastatic castration-resistant prostate cancer (mCRPC) genomes have not yet been fully studied. We aimed to investigate transcriptomic, mutational, and clinical differences by race in a large multi-institutional cohort of men with mCRPC. Methods: Genomic and clinicopathologic data from four mCRPC tumor biopsy cohorts were obtained and aggregated. Gene set enrichm
BACKGROUND AND AIMS: Adhering to the EAT-Lancet diet has been observed to be associated with lower risks of various morbidities. This study aimed to investigate the association of adhering to the EAT-Lancet diet with incident chronic obstructive pulmonary disease (COPD) and identify plasma proteins mediating such association.METHODS: This prospective study involved 202 340 participants free of COP
COSM38: Religion and Society in East and Southeast Asia Autumn Semester 2023 Total number of pages: 1120 (approx.) Consisting of required reading (871) plus additional readings to account for the ongoing developments in the field and across religious landscape in East and Southeast Asia and new emerging scholarship (250 approx). Course literature: Abrahms-Kavunenko, Saskia. 2019. "Introduction." I
https://www.ht.lu.se/media/utbildning/dokument/kurser/COSM38/20232/COSM38.docx - 2026-06-29
Bachelor’s Dissertation Structural Mechanics Report TV SM -4007 C H RISTIA N EBO RN & FILIP A N D ERSSO N FÖ R TÄ TN IN G G EN O M PÅ B Y G G N A D - U tred n in g m ed h än syn till b ärfö rm åg easp ekter CHRISTIAN EBORN & FILIP ANDERSSON FÖRTÄTNING GENOM PÅBYGGNAD Utredning med hänsyn till bärförmågeaspekter 4007HO.indd 14007HO.indd 1 2019-06-13 13:57:562019-06-13 13:57:56 DEPARTMENT OF CONSTRU
https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm4000/web4007.pdf - 2026-06-29
COSM38: Religion and Society in East and Southeast Asia Autumn Semester 2023 Total number of pages: 1120 (approx.) Consisting of required reading (871) plus additional readings to account for the ongoing developments in the field and across religious landscape in East and Southeast Asia and new emerging scholarship (250 approx). Course literature: Abrahms-Kavunenko, Saskia. 2019. "Introduction." I
https://www.historiska.lu.se/media/utbildning/dokument/kurser/COSM38/20232/COSM38.docx - 2026-06-28
Centrality – Regionality The Social Structure of Southern Sweden during the Iron Age EDITED BY LARS LARSSON AND BIRGITTA HÅRDH UPPÅKRASTUDIER 7 ACTA ARCHAEOLOGICA LUNDENSIA SERIES IN 8°, No. 40 The following information can be found in the printed version: The cover picture shows a round copper alloy brooch from the Merovingian Period, detector find from Uppåkra. © The Department of Archaeology an
