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Hereditary defects of the von Willebrand factor (VWF) gene cause von Willebrand's disease (VWD) which shows great variability dependent on the nature and location of the mutation. We here describe the characteristics of a substitution of methionine for threonine 1156 in the D3 domain of the VWF, i.e. the domain involved in the intracellular multimerization of pro-VWF dimers. A VWD patient withseve
Objective: Five double-blind, randomized, saline-controlled trials (RCTs) were included in the United States marketing application for an intra-articular hyaluronan (IA-HA) product for the treatment of osteoarthritis (OA) of the knee. We report an integrated analysis of the primary Case Report Form (CRF) data from these trials. Method. Trials were similar in design, patient population and outcome
This study reports the outcome of active surveillance in men with PSA screening-detected prostate cancer (PC), and PSA doubling time (PSADT) was evaluated as a predictor of selecting patients to active treatment or surveillance. On December 31, 1994, 10,000 men were randomized to biennial PSA testing. Through to December 2004, a total of 660 men were diagnosed with PC, of whom 270 managed with ini
The cystatin C gene (CST3) encodes a low-molecular-weight cysteine proteinase inhibitor belonging to family II of the cystatin super family and is mutated in cases of hereditary cystatin C amyloid angiopathy (HCCAA). CST3, which along with other family II cystatin genes is a member of the cystatin gene family, has been assigned to chromosome 20. To investigate the genomic organization on chromosom
Background: The national programs for the harmonization of hemoglobin (Hb)A(1c) measurements in the US [National Glycohemoglobin Standardization Program (NGSP)], Japan [Japanese Diabetes Society (JDS)/Japanese Society of Clinical Chemistry (JSCC)], and Sweden are based on different designated comparison methods (DCMs). The future basis for international standardization will be the reference system
Stem cells are unspecialized cells able to divide and produce copies of themselves and having the potential to differentiate, i.e. to produce other cell types in the body. Because of the latter ability, the scientists investigate their possible use in regenerative medicine. Especially embryonic stem cells have huge therapeutic potential because they can give rise to every cell type in the body as
Objective: The European Society for Vascular Surgery (ESVS) has developed clinical practice guidelines for thecare of patients with diseases of the mesenteric and renal arteries and veins, in succession to the first 2017guidelines, with the aim of assisting physicians and patients in selecting the best management strategy.Methods: These guidelines are based on scientific evidence and expert opinio
Background: The increased prevalence of atopic diseases may be due to lifestyle changes affecting our exposure to microbes. We investigated the association between infections, fever, and atopic diseases in a large international birth cohort setting. Methods: 3842 children at genetic risk for type 1 diabetes were followed prospectively for the first 10 years for the occurrence of infections and ato
Special Area Studies, Autumn 2025 Special Area Studies ACCESSIBLE TO ALL EXCHANGE STUDENTS, AUTUMN 2025 SAS COURSE AT THE JOINT FACULTIES OF HUMANITIES AND THEOLOGY Information may be requested from: international@ht.lu.se | Webpage: www.ht.lu.se/en/international/ MONDAY A.M. SASH62 Communism in East and Central Europe – Present, Past and Future Perspectives 1 September – 8 December 10.15 – 12.00
Centre for Economic Demography Lund University School of Economics and Management P.O. Box 7083 SE-220 07 Lund, Sweden www.ed.lu/publications/Lund-Papers-in-Economic-Demography/ Unpaid Care for Elderly Parents and Labor Supply Among Older Working-Age Men and Women Across Europe ELISA LABBAS, MARIA STANFORS LUND PAPERS IN ECONOMIC DEMOGRAPHY 2022:4 Unpaid care for elderly parents and labor supply a
https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-01/LPED%202022%204.pdf - 2026-07-01
Purpose: Assess if cystatin C-derived measures of kidney function are associated with mortality in septic- and non-septic intensive care unit (ICU) patients. Methods: Data from adult patients staying >24 h in four ICUs in Sweden from November 2015–December 2018 included. Outcomes were mortality and need for renal replacement therapy (RRT) due to acute kidney injury. Associations between cystatin C
A search is presented for direct pair production of the stop, the supersymmetric partner of the top quark, in a decay through an Formula Presented-parity violating coupling to a charged lepton and a Formula Presented-quark. The dataset corresponds to an integrated luminosity of Formula Presented of proton-proton collisions at a center-of-mass energy of Formula Presented collected between 2015 and
Kurslitteratur MVEN16_HT16_31okt16 Kurslitteratur MVEN16, HT16 2016-10-31 MVEN16 KURSLITTERATUR, HT16 OBS! Fler artiklar, bokkapitel och rapporter kan tillkomma under kursens gång. Kursböcker Boyce, T. And J. Lewis, eds. (2009). Climate Change and the Media. Global Crises and the Media Series. Peter Lang Pub Inc. Bulkeley, H. and P. Newell (2015). Governing Climate Change. 2nd Ed. Routledge. (e-bo
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/kurslitteratur_mven16_ht16.pdf - 2026-07-01
Aerosols from volcanic eruptions impact our climate by influencing the Earth's radiative balance. The degree of their climate impact is determined by the location and injection altitude of the volcanic SO2. To investigate the importance of utilizing correct injection altitudes, we ran climate simulations of the June 2009 Sarychev eruptions with three SO2 datasets in the Community Earth System Mode
Background-beta-Adrenergic stimulation is the main trigger for cardiac events in type 1 long-QT syndrome (LQT1). We evaluated a possible association between ion channel response to beta-adrenergic stimulation and clinical response to beta-blocker therapy according to mutation location. Methods and Results-The study sample comprised 860 patients with genetically confirmed mutations in the KCNQ1 cha
This paper reports on a search for narrow resonances in diboson production in the [Formula: see text] final state using [Formula: see text] collision data corresponding to an integrated luminosity of [Formula: see text] fb[Formula: see text] collected at [Formula: see text] TeV with the ATLAS detector at the Large Hadron Collider. No significant excess of data events over the Standard Model expect
Reindeer husbandry has long been a central element of the traditional livelihood and culture of indigenous Sami people in northern Sweden. However, it faces several challenges from competing land uses, primarily forestry. Different forest conditions are desired by forestry and reindeer husbandry to accommodate each sectors’ distinct interests, promoting high timber and pulp production or improved
The global pandemic of Covid-19 has drastically changed the behaviour of citizens around the world. This research aims to identify actions that ensure low-carbon, inclusive forms of mobility that respond to the behavioural changes during Covid-19. The city of Hamburg, Germany, and its problems with transport-related emissions and socio-economic inequalities serve as a representative case study. Th
The Swedish rules for closely held companies were enacted to combat income conversion abuse in limited liability companies where natural persons acted as both owners and employees. In the Swedish Income Tax Act, employment income is taxed according to a progressive rate while capital income is taxed according to a flat rate. The wage remuneration rule may increase the amount of dividend that the a
