Filtyp
Background: Observational studies suggest an inequitable prescription of biologics in psoriasis care, which may be attributed to geographical differences in treatment access. Sweden regularly ranks high in international comparisons of equitable healthcare, and is, in connection with established national registries, an ideal country to investigate potential inequitable access. Objective: The aim wa
Aim: To estimate the effects of targeted elimination of environmental barriers (EB) in the ordinary housing stock in Sweden, and to explore the estimated effects on accessibility at a population level in relation to (a) residents with different functional profiles, (b) different housing types and (c) building periods. Method: Data on dwellings from existing Swedish research databases were utilized
Variants in HNF1A encoding hepatocyte nuclear factor 1a (HNF-1A) are associated with maturity-onset diabetes of the young form 3 (MODY 3) and type 2 diabetes. We investigated whether functional classification of HNF1A rare coding variants can inform models of diabetes risk prediction in the general population by analyzing the effect of 27 HNF1A variants identified in well-phenotyped populations (n
Although they are often subjected to critical scrutiny, formal geopolitical practices have rarely been put on trial. One exception is the case of Gudmund Hatt (1884-1960), professor of human geography at Copenhagen University from 1929 to 1947, who was found guilty of “dishonorable national conduct” for his geopolitics during the German occupation. As a contribution to the critical history of geop
Background and purpose — The proximal femur locking compression plate (PF-LCP) is a new concept in the treatment of hip fractures. When releasing new implants onto the market, biomechanical studies are conducted to evaluate performance of the implant. We investigated the relation between biomechanical and clinical studies on PF-LCP. Methods — A systematic literature search of relevant biomechanica
Mycket har skett i jordbruket det senaste århundradet. Vi har rört oss från ett småbondesamhälle till ett mekaniserat, industrialiserat och kapitaliserat jordbrukssamhälle med en global marknad. Denna intensifiering av jordbruket har lett till förlust och fragmentering av biotoper vilket givetvis har påverkat den biologiska mångfalden negativt. När arter minskar eller försvinner riskerar vi även aModern agricultural practices have led to an intensification of the agricultural landscape which has negatively affected both biodiversity and the ecosystem services it provides. In my thesis I have used ecological theory of optimal foraging to try and explain how landscape structure, landscape composition and agricultural management can explain the loss of biodiversity and how remedies can effici
This study examines the influence of the victim’s immigration status, perpetrator’s immigration status, and participant’s immigration status on victim and perpetrator blame attributions. In addition, comparisons between men and women were made. Participants read a rape vignette in the form of a newspaper article and subsequently attributed victim and perpetrator blame. A 2 (victim’s immigration st
Migratory birds are known to be capable of adjusting their heading direction to compensate for wind drift and their airspeed adaptively with respect to head and tail winds. High-flying nocturnally migrating common swifts, Apus apus, have been shown to compensate for wind drift, but they failed to adjust airspeed as expected (increase in head wind and decrease in tail wind in relation to neutral wi
The ability of calcium to suppress the secretion of parathyroid hormone (PTH) is impaired in primary hyperparathyroidism (pHPT). Whether the nonadenomatous glands in pHPT also exhibit altered calcium/PTH homeostasis is not known, but this may be the case since in the immediate postoperative period after surgery for pHPT, hypocalcemia often evolves in spite of a rapid normalization of serum levels
Objectives: We have observed clinical cases where bone is formed in the overlaying muscle covering surgically created bone defects treated with a hydroxyapatite/calcium sulphate biomaterial. Our objective was to investigate the osteoinductive potential of the biomaterial and to determine if growth factors secreted from local bone cells induce osteoblastic differentiation of muscle cells. Materials
Petrographic analysis of eight CM carbonaceous chondrites (EET 96029, LAP 031166, LON 94101, MET 01072, Murchison, Murray, SCO 06043, QUE 93005) by electron imaging and diffraction, and X-ray computed tomography, reveals that six of them have a petrofabric defined by shock flattened chondrules. With the exception of Murchison, those CMs that have a strong petrofabric also contain open or mineraliz
Clasts in the CM2 carbonaceous chondrite Lonewolf Nunataks (LON) 94101 have been characterized using scanning and transmission electron microscopy and electron microprobe analysis to determine their degrees of aqueous alteration, and the timing of alteration relative to incorporation of clasts into the host. The provenance of the clasts, and the mechanism by which they were incorporated and mixed
A selection of searches by the ATLAS experiment at the LHC for the electroweak production of SUSY particles are used to study their impact on the constraints on dark matter candidates. The searches use 20 fb−1 of proton-proton collision data at s=8 TeV. A likelihood-driven scan of a five-dimensional effective model focusing on the gaugino-higgsino and Higgs sector of the phenomenological minimal s
When introduced in 1992, the Lund concept (LC) was the first complete guideline for treatment of severe traumatic brain injury (s-TBI). It was a theoretical approach, based mainly on general physiological principles-i.e., of brain volume control and optimization of brain perfusion and oxygenation of the penumbra zone. The concept gave relatively strict outlines for cerebral perfusion pressure, flu
Lung diseases impose a huge economic and health burden worldwide. A key aspect of several adult lung diseases, such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD), including emphysema, is aberrant tissue repair, which leads to an accumulation of damage and impaired respiratory function. Currently, there are few effective treatments available for these disea
Background: Nephrolithiasis (NL) is known to be associated with gout, although there are few comparative studies on risk and risk factors for NL in gout compared to population cohorts. In this cohort study we investigated: (1) overall incidence of NL in gout (cases) and general population controls; (2) risk and risk factors (common comorbidities and medications) for first-time NL in cases and cont
Nutritional epidemiology is an inherently complex and multifaceted research area. Dietary intake is a complex exposure and is challenging to describe and assess, and links between diet, health, and disease are difficult to ascertain. Consequently, adequate reporting is necessary to facilitate comprehension, interpretation, and generalizability of results and conclusions. The STrengthening the Repo
