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Role of Amide Proton Transfer Weighted MRI in Predicting MGMTp Methylation Status, p53-Status, Ki-67 Index, IDH-Status, and ATRX Expression in WHO Grade 4 High Grade Glioma

Objectives: To assess amide proton transfer weighted (APTw) MR imaging capabilities in differentiating high-grade glial tumors across alpha-thalassemia/mental retardation X-linked (ATRX) expression, tumor-suppressor protein p53 expression (p53), O6-methylguanine-DNA methyltransferase promoter (MGMTp) methylation, isocitrate dehydrogenase (IDH) status, and proliferation marker Ki-67 (Ki-67 index)

eHealth as an Aid for Facilitating and Supporting Self-Management in Families with Long-Term Childhood Illness; Development, Evaluation, and Implementation in Clinical Practice

Introduction eHealth, defined by WHO as: “the transfer of health resources and healthcare by electronic means” are expected to increase communication between healthcare providers and patients and increase accessibility and patient participation in healthcare. The aim of this research programme is to: 1) develop a sustainable multidisciplinary environment for advancing, evaluating, and implementing

Meningioma microstructure assessed by diffusion MRI : An investigation of the source of mean diffusivity and fractional anisotropy by quantitative histology

BACKGROUND: Mean diffusivity (MD) and fractional anisotropy (FA) from diffusion MRI (dMRI) have been associated with cell density and tissue anisotropy across tumors, but it is unknown whether these associations persist at the microscopic level.PURPOSE: To quantify the degree to which cell density and anisotropy, as determined from histology, account for the intra-tumor variability of MD and FA in

EMA-based head movements and phrasing : a preliminary study

In this paper we describe present work on multimodal prosody by means of simultaneous recordings of articulation and head movements. Earlier work has explored patterning, usage and machine-learning based detection of focal pitch accents, head beats and eyebrow beats through audiovisual recordings. Kinematic data obtained through articulography allows for more comparable and accurate measurements, In this paper we describe present work on multimodal prosody by means of simultaneous recordings of articulation and head movements. Earlier work has explored patterning, usage and machine-learning based detection of focal pitch accents, head beats and eyebrow beats through audiovisual recordings. Kinematic data obtained through articulography allows for more comparable and accurate measurements,

En idé analys av debatten om svenska militära insatsen i Afghanistan

Uppsatsen handlar om en analys av debatten kring den svenska militära insatsen i Afghanistan året 2010 då tre svenska soldater respektive en afghansk tolk stupade samt flera andra svenska soldater skadades. Till följd av detta, uppstod debatten på Aftonbladet (AB) mellan Jan Guillou och Jan Eliasson, på Svenska Dagbladet (SvD) uppstod debatten mellan Maria-Pia Boëthius och Carl Bildt och på Dagens

Finite element analysis for simplified thermal dose planning in interstitial laser thermotherapy

The objective was to investigate if diffusing laser fibres can be modelled as conductive heat sources without miscalculating coagulated volumes, and if finite element analysis, disregarding light transport, may be used for three dimensional (3D) treatment planning in interstitial laser thermotherapy (ILT). Temperature distributions and coagulated volumes with a diffusing laser fibre, as compared t

Why Goffman Never Made it into the Swedish Textbooks (paper)

This paper investigates to what extent and how the sociological perspective of Erving Goffman is represented in Swedish sociology-textbooks and why it is represented the way it is. The investigation has been restricted to central Swedish textbooks during the period 1970-2000 and consequently it does not give a complete picture, but since the choice of textbooks reflects central currents and person

United States extraterritorial application of economic sanctions and the new international sanctions against Iran

Economic sanctions are defined as the exercise of pressure by one state to produce a change in the political behaviour of another state. Traditional economic sanctions are directed at the entire population of a state whilst targeted sanctions are directed at a state’s individuals. This thesis discusses the application of economic sanctions against Iran by the UN, the EU and the United States. Econ

Immunogenetics of Childhood Type 1 Diabetes in Immigrant Patients in Sweden. Migration Studies on Type 1 Diabetes

Popular Abstract in Swedish Syfte Syftet med denna avhandling var att undersöka om barn födda i Sverige till invandrare (icke-Svenskar) hade en ökad risk för typ 1 diabetes (T1D) och om immunogenetiska markörer för T1D (HLA och icke-HLA genetiska faktorer samt ö-cellsantikroppar) skiljde sig från svenska T1D barn (Svenskar). Målsättningen var också att analysera ärftliga förutsättningar (T1D och TThis thesis examined whether the offspring of immigrants (non-Swedes) to Sweden are at increased risk of Type 1 Diabetes (T1D) when they are born or live in Sweden. It also evaluated if their T1D and T2D-related genes differed from Swedish patients and whether this genetic heritage determined the types and existence of islet autoantibodies at time of diagnosis and affected the classification of di