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Predictive models used in decision making, such as QSARs in chemical regulation or drug discovery, call for evaluated approaches to quantitatively assess associated uncertainty in predictions. Uncertainty in less reliable predictions may be captured by locally varying predictive errors. In the current study, model-based bootstrapping was combined with analogy reasoning to generate predictive distr
BACKGROUND: Autoantibodies are common in glomerulonephritis, but the clinical benefit of rapid elimination is not determined, even in anti-glomerular basement membrane (GBM) disease. Even less is known about the importance of autoantibody characteristics, including epitope specificity and IgG subclass distribution. By utilizing samples from the GOOD-IDES-01 trial, where imlifidase, cleaving all Ig
Ecosystem functioning depends on biodiversity at multiple trophic levels, yet relationships between multitrophic diversity and ecosystem multifunctionality have been poorly explored, with studies often focusing on individual trophic levels and functions and on specific ecosystem types. Here, we show that plant diversity can affect ecosystem functioning both directly and by affecting other trophic
Popular Abstract in Swedish Akrylatallergi Plastmaterial består av stora molekyler som kallas polymerer samt tillsatsämnen som tillsätts för att modifiera materialets egenskaper. Polymerer bildas när det sker en stegvis reaktion mellan monomerer så att större molekyler bildas. Allergiframkallande ämnen i plastsystem kan vara monomererna, härdarna, modifierarna eller andra tillsatsämnen. AkrylaterAcrylate contact allergy has been frequently reported since the 1970s, with hundreds of articles published in dermatology journals so far. The purpose of this thesis was to investigate the frequency of contact allergy to acrylates / methacrylates in patients with exposure to industrial, dental and nail uses of these substances. We also aimed to investigate the clinical and chemical aspects of pa
The consequences of climate change for bird populations have received much attention in recent decades, especially amongst cavity-nesting songbirds, yet little has been written on ducks (Anatidae) despite these being major elements of wetland diversity and important quarry species. This paper reviews the major known consequences of climate change for birds in general, and relates these to the limi
Agricultural fertilisation increases crop yields but can cause environmental damage, thus reductions in inorganic fertiliser application have been advocated. Farmer usage of phosphate rock has declined over the last decade, which may lead to soil nutrient depletion that undermines future crop production. We investigated the long-term (55 years) effects of eight different inorganic fertiliser regim
There is increasing interest in the use of arbuscular mycorrhizal fungi (AMF) for ecological restoration, as AMF can improve plant nutrition and growth. However, some AMF can have negative effects on plant growth. It is therefore critical that restoration strategies incorporate appropriate AMF. This research investigated differences in growth and survival of Podocarpus cunninghamii (mountain tōtar
Plant size is a major predictor of ecological functioning. We tested the hypothesis that feeding damage to plants increases with plant size, as the conspicuousness of large plants makes resource finding and colonisation easier. Further, large plants can be attractive to herbivores, as they offer greater amounts and ranges of resources and niches, but direct evidence from experiments testing size e
To address the problems of climate change and energy security, Chinese government strived to develop renewable power as an important alternative of conventional electricity. In this paper, the learning curve model is employed to describe the decreasing unit investment cost due to accumulated installed capacity; the technology diffusion model is used to analyze the potential of renewable power. Com
OBJECTIVES: To evaluate the long-term benefits of progressive resistance training in chronic stroke. DESIGN: A 4-year follow-up of a randomized controlled trial of progressive resistance training. SUBJECTS: Eighteen women and men (mean age 66 (standard deviation 4) from the original group of 24 post-stroke participants. METHODS: The training group (n = 11) had participated in supervised progres
At low temperature, cell membrane functionality depends on adjustments of membrane phospholipid fatty acid (PLFA) composition. We here test the hypothesis that previous exposure to copper (Cu) may deteriorate tolerance to freezing temperatures because of Cu-induced changes of PLFA composition of cell membranes in the freeze-tolerant earthworm Dendrobaena octaedra. Cu levels and freezing temperatur
Scenario: Using adaptive dynamic theory, expose a monomorphic prey population to two habitat types and a visual predator. Questions: What circumstances can lead to the evolution of polymorphic crypsis? How is the outcome affected by the dispersal pattern of the prey and predator, by the amount of predation, and by the trade-off strength between the habitats? Mathematical method: I modelled three d
It is relevant to consider uncertainty in individual predictions when quantitative structure-activity (or property) relationships (QSARs) are used to support decisions of high societal concern. Successful communication of uncertainty in the integration of QSARs in chemical safety assessment under the EU Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) system can be faci
A dynamic coupled biogeochemical-ecological model was used to simulate the effects of nitrogen deposition and climate change on plant communities at three forest sites in France. The three sites had different forest covers (sessile oak, Norway spruce and silver fir), three nitrogen loads ranging from relatively low to high, different climatic regions and different soil types. Both the availability
The voluntary nature of programs that pay landowners for conservation measures raises the question of what factors favor participation in such programs. This article focuses on the controversial issue of the impact of information on the participation decision. We develop a straightforward model to analyze how information affects this decision, and empirically estimate the impact of information, as
This study investigates the environmental impact from dog food and cat food produced in Sweden. With over 2.5 million dogs and cats in Sweden the potential environmental effect from their food is relevant to investigate. The aim of this study is therefore to quantify the environmental impact of 1 kg dog and cat food sold by Granngården. This has been done with the life cycle assessment (LCA) metho
Lake Vomb is situated in the southwest of Skåne, Sweden, and is important due to its role as drinking water reservoir. The lake is situated in highly cultivated farmland and is highly influenced by nutrient rich run-off water. There is no locally adapted water management plan for lake Vomb and the lake is currently managed under a regional water management plan which covers the entire Southern B
Grobruket is a small company that works with cultivation in many ways and they are very aware of their climate footprint. Therefore, they are also interested in taking a deeper look into the environmental impact of different covering materials used for greenhouses. The most common covering materials used in greenhouses are glass, ethylene vinyl acetate plastic (EVA) and polycarbonate plastic. The
The wolf topic is subject for considerable controversy in Sweden. Today, wolves are recognized, by the IUCN redlist, as locally endangered and what is more, the Swedish population suffers from ample inbreeding. However, between 2010-2022 license hunts have been allowed on an almost yearly basis, albeit not without numerous appeals. Because the wolf is strictly protected under the European Unio
The Swedish consumers consumed in 2014 13.1 kilo textilies, of this 8 kilogram was dicarded via household waste and used for energy production. European Union’s waste hierarchy avocates a higher rate of reuse and recycling for a more sustainable textile flow. The Swedish goverment is, therefor, working toward new laws and guidelines which can lead to an expanded responsibility for the municipaliti
