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To understand the origin of disease risk in adulthood, factors in all stages of life and on different contextual levels should be considered. Therefore, the aim of this study was to investigate the relevance of a person's area of residence over their life course with regard to four outcomes: all-cause mortality; ischemic heart disease mortality and morbidity; cancer mortality and morbidity; and re

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Hydroelectric power is a controversial renewable energy. Adding more renewables to the energy mix is becoming more critical with the onslaught of climate change, while river health and water quality remain a highly pertinent environmental issue. Balancing the need for local renewable energy and environmental concerns is the topic of many cases. This thesis analyzes a case of conflict surrounding t

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Global dependence on fossil fuels encourages the depletion of non-renewable resources, produces greenhouse gas emissions, and ultimately contributes to anthropogenic climate change. Current efforts do not reduce depletion rates of these non-renewable resources despite collective action to improve long-term sustainability of Norwegian energy governance in the Barents Sea. This study focuses on the

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I detta examensarbete analyseras och diskuteras de omfattande förändringar inom rättsområdet grundläggande rättigheter som följt efter att Lissabonfördraget trädde i kraft den 1 december 2009. Arbetet är avgränsat till att beskriva de förändringar som art. 6.1 och art. 6.2 i Fördraget om Europeiska Unionen (FEU) inneburit. Enligt art. 6.1 ska den Europeiska Unionens Stadga om de Grundläggande RättThis thesis analyses and discusses some of the substantial changes brought about for the field of fundamental rights by virtue of the entry into force of the Lisbon Treaty 1 December 2009; Art. 6(1) to the Treaty on European Union (TEU), according to which the Charter of Fundamental Rights of the European Union (CFREU) “shall have the same legal value as the Treaties” and Art. 6(2) TEU according t

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Senegalese smallholders up to date face high constraints regarding their generation of livelihoods from agriculture. Restricted access to productive resources and participation in finance, input and output markets are root causes for these constraints. While the potential of collective action to address institutional constraints of smallholder agriculture has been widely acknowledged, success sto

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De senaste 15-20 åren har övervikt och fetma blivit ett växande folkhälsoproblem i västvärlden. Befolkningen har en allt mer stillasittande fritid och en tredjedel uppfyller inte den föreslagna rekommendationen om 30 minuters fysisk aktivitet om dagen. Användning av stegräknare kan vara ett sätt att motivera och inspirera till ökad fysisk aktivitet. På ett stort processföretag med dag- och skift a

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The Öresund Region, comprising areas of Sweden and Denmark, is involved in a process of sustainable urban transformation. The region has high ambitions in terms of carbon emissions reduction and has set itself steep targets to meet over the next 15-20 years. The energy consumption of buildings accounts for a significant proportion of carbon emissions. With the urban areas of the Öresund Region exp

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Background: Rat pups are born with an immature intestine adapted for the effective uptake of milk nutrients and with high permeability for bioactive molecules from the maternal milk until weaning. During weaning the immune system is activated after stimulation with e.g. dietary antigens, leading to an inflammatory response in the gut. This response is believed to be important for progress of gut m

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This thesis seeks to answer what causes some governments to restrict foreign funding to domestic civil society organizations while others do not. These repressive measures have increased significantly in all regions of the globe recently and existing research has yet to provide an encompassing explanation for the trend. Considering that neither foreign funding or government repression are exactly

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Due to a warming climate, tundra ecosystems are subject to shrub and treeline expansions which could lead to increased above- but decreased belowground carbon (C) stocks. An observed low soil C stock in some subarctic forests and tall shrublands has been suggested to be induced by priming of organic matter decomposition, possibly mediated by ectomycorrhizal fungi. On the other hand, the higher bel

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The purpose of this study was to determine whether delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) and T2 mapping are accurate techniques for measuring cartilage thickness in the metacarpus3/metatarsus3 (Mc3/Mt3) of Thoroughbred racehorses. Twenty-four Mc3/Mt3 cadaver specimens were acquired from six healthy racehorses. Cartilage thickness was measured from postintra-

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The purpose of this study was to assess the reliability and construct validity of the Spanish version of the 6-item carpal tunnel syndrome (CTS) symptoms scale (CTS-6).

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Prostate specific antigen (PSA) is an important biomarker for diagnosis and prognosis of prostate cancer. Herein, microcontact PSA-imprinted surface plasmon resonance (SPR) sensor chip was developed for sensitive, real-time detection of PSA. The imprinted chip was prepared in the presence of methacrylic acid (MAA) as functional monomer and ethylene glycol dimethacrylate (EGDMA) as cross-linker via

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Environmental conditions, dispersal lags, and interactions among species are major factors structuring communities through time and across space. Ecologists have emphasized the importance of biotic interactions in determining local patterns of species association. In contrast, abiotic limits, dispersal limitation, and historical factors have commonly been invoked to explain community structure pat

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The incretin - glucose-dependent insulinotropic polypeptide (GIP) - and the pro-inflammatory cytokine osteopontin are known to have important roles in the regulation of adipose tissue functions. In this work we show that GIP stimulates lipogenesis and osteopontin expression in primary adipocytes. The GIP-induced increase in osteopontin expression was inhibited by the NFAT (the transcription factor

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Background: Long-term exposure to air pollution is a hypothesized risk factor for ischemic stroke. In a large case-control study with a complete study base, we investigated whether hospital admissions for ischemic stroke were associated with residential concentrations of outdoor NOx, as a proxy for exposure to air pollution, in the region of Scania, Southern Sweden. Methods: We used a two-phase ca

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Background: Cohort studies of the relationship between air pollution exposure and chronic health effects require predictions of exposure over long periods of time. Objectives: We developed a unified modeling approach for predicting fine particulate matter, nitrogen dioxide, oxides of nitrogen, and black carbon (as measured by light absorption coefficient) in six U.S. metropolitan regions from 1999

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A bioanode with high current density and coulombic efficiency was developed by co-immobilization of pyranose dehydrogenase from Agaricus meleagris (AmPDH) with the dehydrogenase domain of cellobiose dehydrogenase from Corynascus thermophiles (recDHCtCDH) expressed recombinantly in Escherichia coli. The two enzymes were entrapped in Os-complex modified electrodeposition polymers (Os-EDPs) with spec

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BackgroundDimethyl sulfoxide (DMSO) is essential for the preservation of liquid nitrogen-frozen stem cells, but is associated with toxicity in the transplant recipient. Study Design and MethodsIn this prospective noninterventional study, we describe the use of DMSO in 64 European Blood and Marrow Transplant Group centers undertaking autologous transplantation on patients with myeloma and lymphoma