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Context Agricultural transformation and increased land use intensity often lead to simplified landscapes and biodiversity loss. For animals, one possible mechanism underpinning biodiversity loss in agricultural landscapes is the disruption of movements. The disruption of movements may explain, for example, why butterfly communities in agricultural landscapes are often dominated by generalist speci
Protein kinase B (PKB)/Akt has been strongly implicated in the insulin-dependent stimulation of GLUT4 translocation and glucose transport in skeletal muscle and fat cells. Recently an allosteric inhibitor of PKB (Akti) that selectively targets PKB alpha and -beta was reported, but as yet its precise mechanism of action or ability to suppress key insulin-regulated events such as glucose and amino a
Recently, primitive human bone marrow (BM) progenitors supporting hematopoiesis in extended (>60 days) long-term BM cultures were identified. Such extended long-term culture-initiating cells (ELTC-IC) are of the CD34(+)CD38(-) phenotype, are quiescent, and are difficult to recruit into proliferation, implicating ELTC-IC as the most primitive human progenitor cells detectable in vitro. However, it
Conference Report from Forum for the Future of Democracy 2007.
A total of 45 subfossil reindeer (Rangifer tarandus) antlers and bones - artefacts excluded - have been found over the years in the Baltic countries of Estonia, Latvia and Lithuania. The relatively high number of specimens suggests a stable residence of the species in the eastern Baltic region. For the first time, 12 of these finds were radiocarbon-dated. The ages of the samples range between 1208
Purpose To explore the effect of high-dose ifosfamide in first-line treatment for patients <= 40 years of age with nonmetastatic osteosarcoma of the extremity. Patients and Methods From March 1997 to September 2000, 182 patients were evaluated. Primary treatment consisted of two blocks of high-dose ifosfamide (15 g/m(2)), methotrexate (12 g/m(2)), cisplatin (120 mg/m(2)), and doxorubicin (75 mg/m(
Background: von Willebrand disease (VWD) type 1 is a congenital bleeding disorder caused by genetic defects in the von Willebrand factor (VWF) gene and characterized by a reduction of structurally normal VWF. The diagnosis of type 1 VWD is difficult because of clinical and laboratory variability. Furthermore, inconsistency of linkage between type 1 VWD and the VWF locus has been reported. Objectiv
A method has been developed for establishing a "University Without Walls" for the purpose of studying the relationship between electrocardiographic estimation and magnetic resonance imaging measurements of myocardial infarct size. The research team includes faculty and students from 4 medical centers, with expertise extending from clinical to technical. Weekly interactive videoconferences provide
[1] The timing of magmatic events forming Jurassic basaltic rocks in Dronning Maud Land (DML), Antarctica, and hydrothermal activity that affected them is addressed with detailed Ar-40/Ar-39 incremental heating dating of feldspars. Plagioclase from an Utpostane gabbro and from a Kirwanveggen dolerite dike yield indistinguishable plateau ages at 177 +/- 1.8 Ma. Because of geologic controls, this es
OBJECTIVES: The aims of our study were to compare the interobserver reproducibility of two-dimensional (2D) and three-dimensional (3D) saline contrast sonohysterography (SCSH) and agreement of these techniques with hysteroscopy, and to determine which SCSH findings best discriminate between benign and malignant endometrium. METHODS: Consecutive women with postmenopausal bleeding and endometrial th
Climate models provide the means of making projections of the future climate, under assumptions on alternative future land-use changes and greenhouse gas emissions. The basis for such climate projections is discussed in this chapter,´together with the presentation of overall climate scenario results of relevance for agriculture. The focus is on the period until 2050.
The Nordic countries have a long tradition of large-scale biobanking and comprehensive, population-based health data registries linkable on unique personal identifiers, enabling follow-up studies spanning many decades. Joint Nordic biobank-based studies provide unique opportunities for longitudinal molecular epidemiological research. The purpose of the present paper is to describe the possibilitie
Det har blivit vardag för allmänheten att dagligen läsa rubriker om sprängningar, skjutningar, mord och narkotikabrott. Dessa brott har ökat de senaste åren, så pass mycket att många inte längre höjer på ögonbrynen när man läser om det i medierna. Osäkerheten och otryggheten i samhället har ökat i takt med att den organiserade brottsligheten har ökat. De senaste åren har den organiserade brottsliIt has become commonplace for the general public in Sweden to read daily news reports about explosions, shootings, homicides, and narcotics related crimes. These types of crimes have increased during the last years, to such an extent that many people do not feel safe. With rising crime rates, there is an increased sense of insecurity and uncertainty. The criminals have adopted new technologies, a
Intellectual property is a very important type of asset in today’s business world. Since business in the Western World grows increasingly based and dependent on know-how and technological development, intangible assets such as trademarks, copyrights and patents plausibly represent greater economic value to economic actors here than other, physical, assets do. Although it is comparatively unknown
Storskaliga våldsamheter mot medlemmar av folkgruppen Rohingya i Myanmar har sedan augusti 2017 lett till över 10 000 människors död och tvingat nära en miljon människor att fly till grannlandet Bangladesh. Som respons på händelserna inledde Gambia i november 2019 förfaranden i Internationella domstolen (ICJ) mot Myanmar och några dagar senare auktoriserades Internationella brottmålsdomstolens (ICAtrocities against members of the Rohingya group in Myanmar have since August 2017 resulted in over 10 000 deaths and close to one million people being forced to flee into neighbouring Bangladesh. In response to these events, The Gambia instituted proceedings against Myanmar before the International Court of Justice (ICJ) in November 2019. A few days later, the Prosecutor of the International Crim
