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Train-induced vibrations in cross-laminated timber buildings : A parametric study

This study explores structural modifications for reducing train-induced vibrations in timber buildings by modifying the building layout. A parameter study was conducted using a semi-analytical ground model coupled with a finite element structural model. The train load was modeled as a stationary oscillating point load of unit magnitude, applied on the ground surface. The analyzed frequency range,

A novel geophysical methodology to characterize past metallurgic sites and deposits

This study is part of a North West Europe (NWE) Interreg project called NWE-REGENERATIS that aims at the regeneration of past metallurgic sites and deposits through innovative circularity for raw materials. A novel geophysical methodology is developed to allow a 2D or 3D characterization of the recoverable metallic particles in terms of volume, type and grain sizes. We propose to integrate multi-m

Getting the word out: : The case of the Glasgow Consensus Statement

This discussion paper recognizes that the Glasgow Consensus Statement is not optimally useful unless it is disseminated widely. Knowledge and use of the consensus statement and its call for centering humanism in healthcare extend to medical and health organizations and groups beyond the International Conference on Communication in Healthcare and Patient Education and Counseling audiences, to profe

Psychiatric inpatient bed capacity and suicide mortality in Sweden: a nationwide ecological study

BackgroundSuicide is a leading cause of premature mortality worldwide, but the impact of system-level mental health resources remains unclear despite the central role of psychiatric inpatient care and declining bed capacity. Prior research has yielded inconsistent findings with limited control for confounding. We aimed to estimate the effect of psychiatric inpatient bed availability on suicide mor

Quantum Information and Computing for Beginners : Basics of Qubit Transformations and Quantum Algorithms

Quantum information and quantum computing are based on the concept and manipulation of qubits. In this pedagogical Tutorial-written with the aim of assisting self-motivated undergraduate mathematics, physics, and engineering students-transformation of these qubits, especially the Hadamard transformation (H) and the phase shifter transformation (φ), is illustrated. Two-qubit gates and their applica

Miljöorganisationers talerätt med stöd av Århuskonventionen : En analys av implementeringen i svensk rätt och dess konsekvenser för enskilda

Artikeln analyserar hur Århuskonventionens tredje pelare om allmänhetens tillgång till rättslig prövning har implementerats i svensk rätt och därefter utvecklats genom EU‑domstolens praxis och svenska domstolsavgöranden. Analysen exemplifierar genom att ta sin utgångspunkt i miljöorganisationers talerätt i skogsbruksfrågor. Lagstiftarens ursprungliga intentioner vid införlivandet (särskilt Ds 2004

Acidosis enhances translocation of protein kinase C but not Ca2+/calmodulin-dependent protein kinase II to cell membranes during complete cerebral ischemia

Systemic hyperglycemia and hypercapnia severely aggravate ischemic brain damage when instituted prior to cerebral ischemia. An aberrant cell signaling following ischemia has been proposed to be involved in ischemic cell death, affecting protein kinase C (PKC) and the calcium calmodulin kinase II (CaMKII). Using a cardiac arrest model of global brain ischemia of 10 min duration, we investigated the

Models for studying long‐term recovery following forebrain ischemia in the rat. 2. A 2‐vessel occlusion model

ABSTRACT— A model is described in which transient ischemia is induced in rats anaesthetized with N2O:O2 (70:30) by bilateral carotid artery clamping combined with a lowering of mean arterial blood pressure to 50 mm Hg, the latter being achieved by bleeding, or by bleeding supplemented with administration of trimetaphan or phentolamine. By the use of intubation, muscle paralysis with suxamethonium

Cortical spreading depression is associated with arachidonic acid accumulation and preservation of energy charge

The present study aimed to study the relation between the release of arachidonic acid (AA) and the energy state in cerebral cortices of rats during single episodes of cortical spreading depression (CSD). The changes in concentrations of AA, labile phosphate compounds [ATP, ADP, AMP, and phosphocreatine (PCr)], and glycolytic metabolites (lactate, pyruvate, glucose, and glycogen) were studied durin

Climate change and transboundary water management in the Tunisian Mellegue Catchment

Human activities and climate change affect hydrological and sedimentological characteristics within catchments. For arid and semiarid areas this induces direct negative economic and environmental consequences on society. In fact, stability in the rainfall regime and less siltation trapped in reservoirs mean more water for irrigation, water supply, and better flood control. This is especially impor

Thermal performance of angled, V-shaped and leaning-V-shaped ribs in a rotating rectangular channel with 45° orientation

Purpose: The fluid flow in a rotating channel is obviously different from that in a stationary channel due to the existence of Coriolis force, which, in turn, enhances the heat transfer on the trailing side and reduces the heat transfer on the leading side. The purpose of this paper is to study various rib configurations combined with channel orientation on heat transfer and frictional loss in a r

Computational analysis of span-wise hole locations on fluid flow and film cooling of internal channels with crescent ribs

Purpose: This study aims to clarify the mechanism of film hole location at the span-wise direction of an internal cooling channel with crescent ribs on the adiabatic film cooling performance, three configurations are designed to observe the effects of the distance between the center of the ellipse and the side wall(Case 1, l = w/2, Case 2, l = w/3 and for Case 3, l = w/4). Design/methodology/appro

Traffic conflicts analyses for 2+1 road sections

The additional passing lanes and 2+1 roads improve significant road safety. Studies indicate sections with additional passing lanes (relief or alternately), which may cause reduction in the number of accidents by 50%. However, how geometric design affects the safety performance of such sections is not in depth investigated. Previous studies are carried out with two approaches, i.e. the most often,

Strain fields and mechanical response of a high to medium fissured bentonite clay

This article presents the developments of an ongoing research aimed at modelling the influence of fissuring on the behaviour of clays. In particular, it recalls the main results of an extensive laboratory investigation on a fissured bentonite clay from the south of Italy and presents the data of a new investigation on the evolution with shearing of the strain fields developing within the clay, res

Laser tumor thermotherapy: Is there a clinically relevant effect on the immune system

Laser thermotherapy is interesting from an immunological point of view since it can reduce tumor volume without causing immunosuppression at the same time as it may induce and/or enhance tumor immunity. In a rat liver tumor model, we have demonstrated that laser thermotherapy 1) is superior to surgical resection, 2) gives a strong rejection immunity associated with an immune cellular response of t

Psychosocial Well-Being of Young People Who Participated in a Support Group Following the Loss of a Parent to Cancer

Despite the evidence of unmet support needs among young people who have lost a parent to cancer, only a few support group initiatives have been reported. This observational prospective study explored the psychosocial well-being of young people who participated in support groups at a Swedish specialist palliative care setting. On three occasions, 29 participants, aged 16–28 years, answered question

INFORMEG, a new evaluation system for family medicine trainees : Feasibility in an Italian rural setting

Introduction: In Italy the course to become a general practitioner (GP) lasts 3 years and includes both theoretical and practical study. Different from the theoretical part, until recently the practical activity has not been assessed at all. The Emilia Romagna Regional Health Authority has developed a special program called INFORMEG (Management of Tutoring during the Triennial Specific Training in