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A suggestion for the quantification of precise and bounded probability to quantify epistemic uncertainty in scientific assessments

An honest communication of uncertainty about quantities of interest enhances transparency in scientific assessments. To support this communication, risk assessors should choose appropriate ways to evaluate and characterize epistemic uncertainty. A full treatment of uncertainty requires methods that distinguish aleatory from epistemic uncertainty. Quantitative expressions for epistemic uncertainty

Understanding and defining programme leadership in a large institution

In this chapter, the authors take a soft-systems methodology (SSM) (Checkland & Poulter, 2006) approach to problematising the role of programme leadership and developing with the learning community far-reaching solutions for effective programme leadership at a UK University. An appreciative inquiry (Cooperrider, 2017) allowed programme leaders (PLs) to describe many aspects of the role they fe

Meristem wall : an exploration of 3d-printed architecture

Meristem Wall is a prototype for a 3D-printed building envelope, featuring a dynamically controllable network of integrated air channels that allow a fluid and adaptive relationship between inside and outside. The wall integrates functional lighting and electricity, windows, and a custom CNC-knitted textile interior. It is fabricated through binder-jet sand 3D printing and points towards a climati

Plasma serotonin levels are associated with antidepressant response to SSRIs

Background: Less than half of patients with major depressive disorder (MDD) respond to their first antidepressant trial. Our understanding of the underlying mechanisms of selective serotonin reuptake inhibitors (SSRIs) remains poor, and there is no reliable method of predicting treatment response. Methods: Thirty-seven MDD subjects and 41 healthy controls, somatically healthy and medication-free f

Bostadsort avgör den palliativa vårdens resurser och kvalitet : Satsningar för att öka kompetensen behövs

Access to palliative care is unequally distributed across Sweden and thus does not meet the needs. The holistic perspective of palliative care is sometimes contrasted with the usual medical focus on organ failure and disease. Palliative consultation teams provide specialist palliative care competencies for staff caring for patients in primary care, nursing homes and in hospitals. Efforts to increa

Novel Pharmacological Targets for Combat PTSD-Metabolism, Inflammation, The Gut Microbiome, and Mitochondrial Dysfunction

INTRODUCTION: Current pharmacological treatments of post-traumatic stress disorder (PTSD) have limited efficacy. Although the diagnosis is based on psychopathological criteria, it is frequently accompanied by somatic comorbidities and perhaps "accelerated biological aging," suggesting widespread physical concomitants. Such physiological comorbidities may affect core PTSD symptoms but are rarely th

Iran’s Killing Machine: Political Assassinations by the Islamic Regime

It was recently revealed that the Iranian regime was planning to assassinate the US ambassador to South Africa. Tehran denied any such plans, but a brief look at the Islamic regime’s history shows that Iran not only has the will but also the means to conduct assassinations on foreign soil.Assassinations and terrorism have been the regime’s modus operandi both at home and abroad ever since the esta

A case study addressing the benefits of daylighting and electric lighting integration in the retail sector

This article describes field monitoring and supplementary simulations of an existing daylighting and electric lighting integrated design for a furniture store. First in its type, the store includes several areas of the showroom provided with abundant daylighting. For the monitoring, the areas of the living rooms and the home decoration exhibitions were selected. They include wide glazed areas, day

Smoking as a risk factor for myelodysplastic syndromes and acute myeloid leukemia and its relation to cytogenetic findings: A case-control study.

In this case-control study, interview data on smoking habits were available for 179 de novo cases (116 with cytogenetic data) of acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). Smoking habits were compared with a pooled set of population controls and hospital controls (diagnosed with malignant melanoma). Each pack-year of smoking increased the risk of MDS with 1.3% (95% CI 0.1-2.6

Swedish Industrial VET and Placements Abroad

This study is part of a larger project that aims at balancing the higher education biased picture of knowledge transfer through international mobility, by emphasising workers on lower educational levels in 20th and 21st century Sweden. The present part study examines the views on experience and knowledge acquired abroad among students at six upper secondary schools connected with Swedish multinati