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This prospective study reports the design and results obtained after the EMPODaT project implementation. This project was funded by the Tempus programme of the European Commission with the objective to implement a common postgraduate programme on organ donation and transplantation (ODT) in six selected universities from Middle East/North Africa (MENA) countries (Egypt, Lebanon and Morocco). The co
Background: The prescribed radiation dose to patients with oropharyngeal squamous cell carcinoma (OPSCC) is standardized, even if the prognosis for individual patients may differ. Easy-at-hand pre-treatment risk stratification methods are valuable to individualize therapy. In the current study we assessed the prognostic impact of primary tumor volume for p16-positive and p16-negative tumors and in
Background: This pilot study aims to test the usability of the iACTwithPain platform, an online ACT-based intervention for people with chronic pain, to obtain information on which intervention and usability aspects need improvement and on expected retention rates. Methods: Seventy-three Portuguese women with chronic pain were invited to complete the first three sessions of the iACTwithPain interve
BackgroundSelf-regulation of payment disclosure by pharmaceutical industry trade groups is a major global approach to increasing transparency of financial relationships between drug companies and healthcare professionals and organisations. Nevertheless, little is known about the relative strengths and weaknesses of self-regulation across countries, especially beyond Europe. To address this gap in
BACKGROUND: Lateral ankle sprain (LAS) is a common and burdensome injury. However, the quality of its management is scant. Nowadays, physiotherapy management of musculoskeletal diseases seems to be generally not based on research evidence. Studies that investigated the knowledge-to-practice gap in LAS management are yet to be carried out. Therefore, this research investigated physiotherapists' kno
Objectives. To design protocols for specific and quantitative immunohistochemical detection of human kallikrein 2 (hK2) using lanthanide chelate-labeled monoclonal antibodies (Mabs) and time-resolved fluorescence imaging. Methods. Anti-prostate-specific antigen (PSA) Mabs were tested in microtiterplate assays for their ability to prevent PSA from cross-reacting with the anti-hK2 Mab 6H10. Europium
This article introduces the Framework for Integrating Rights and Equality (FIRE): a transdisciplinary framework that builds synergies between human rights-based (HRBA) and gender equality approaches to disaster risk reduction (DRR) and climate change adaptation (CCA). It describes how FIRE has been developed, tested and refined over the course of a five-year regional learning and technical coopera
Objectives: To develop EULAR recommendations for screening and prophylaxis of chronic and opportunistic infections in patients with autoimmune inflammatory rheumatic diseases (AIIRD). Methods: An international Task Force (TF) (22 members/15 countries) formulated recommendations, supported by systematic literature review findings. Level of evidence and grade of recommendation were assigned for each
BACKGROUND: Hemophilia A and B are caused by variants in the factor (F) VIII or FIX gene. Selective reporting may influence the distribution of variants reported in genetic databases.OBJECTIVES: To compare the spectrum of F8 and F9 variants in an international population-based pediatric cohort (PedNet Registry) with the spectrum found in the European Association for Haemophilia and Allied Diso
Psychosocial treatments improve outcome in Pediatric bipolar disorder (PBD), but few are developed specifically for adolescents and none has been evaluated in Europe. This study evaluates family-focused cognitive-behavioral therapy for adolescents (ages 13-18) with PBD in routine psychiatric care in Sweden, adapted for teenagers in a European setting from the Child and Family-Focused Cognitive Beh
Urban green spaces are important for climate change adaptation, in particular to reduce the negative impacts of heat waves on human well-being. However, in growing cities urban green spaces are under pressure due to increasing housing demand and densification. Municipalities face the challenge of addressing both the housing shortage and the need for climate change adaptation on limited space. This
Migration has a global impact, but it also intersects with local and nationalissues. In 2020, 281 million people lived outside their country of birth or citizenship, according to the United Nations Global Migration Database. The number of persons displaced across international borders is increasing due to conflict, persecution, and violence. Most of the world’s refugees and asylum seekers live i
This paper uses the notion of material affordances to show that a focus on how people engage with materials helps understanding how organizations transit toward sustainability. Material affordances refer to the enablements and constraints afforded by materials to someone engaging with an environment for a particular purpose. Based on a qualitative study of a company's efforts at becoming circular,
Substance P (SP) and calcitonin gene-related peptide (CGRP) have both been considered potential drug candidates in migraine therapy. In recent years, CGRP receptor inhibition has been established as an effective treatment, in particular as a prophylactic for chronic migraine. Curiously, inhibition of neurokinin receptor 1 (NK1R) failed to alleviate acute migraine attacks in clinical trials, and th
Cardiometabolic diseases are the leading preventable causes of death in most geographies. The causes, clinical presentations, and pathogenesis of cardiometabolic diseases vary greatly worldwide, as do the resources and strategies needed to prevent and treat them. Therefore, there is no single solution and health care should be optimised, if not to the individual (ie, personalised health care), the
For centuries, teaching classical instruments has exclusively relied on one-to-one tuition also when teaching young children. While this form of teaching has dominated Swedish Art and Music Schools (SAMS), lately there has been an increasing political, economic, and educational interest in group tuition. SAMS are publicly funded by the municipalities to be affordable also for children whose parent
