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Introduction Randomised controlled trials (RCTs) conducted using cohorts and routinely collected health data, including registries, electronic health records and administrative databases, are increasingly used in healthcare intervention research. The development of an extension of the CONsolidated Standards of Reporting Trials (CONSORT) statement for RCTs using cohorts and routinely collected heal

In my thesis I present the work of the Japanese artist Takashi Murakami and the British street artist Beejoir, both of whom have done work involving the trademark monogram pattern of Louis Vuitton. Through my analysis of central parts of Murakami's body of work, I show how his cooperation with Louis Vuitton constitutes an ideal symbiosis where the carefree luxury of the Vuitton brand is comple

OBJECTIVE: To evaluate if opioid-free anaesthesia (OFA), is non-inferior to standard of care (SOC), in patients at low risk for acute postoperative pain (APOP).DESIGN: Patient- and assessor-blinded, non-inferiority, randomised, controlled trial.SETTING: Single centre between March 2022 to February 2024.PATIENTS: 154 adult patients, ASA I - II, planned for elective laparoscopic surgery and risk-cla

Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival through activation of TrkB receptors. The trkB gene encodes a full-length receptor tyrosine kinase (TrkB.FL) and its truncated (T1/T2) isoforms. We investigated the changes in TrkB protein levels and signaling activity under excitotoxic conditions, which are characteristic of brain ischemia, traumatic brain injur

OBJECTIVES: To determine the ability to correctly identify Cesarean section scars, to estimate the prevalence of defective scars, and to determine the size and location of scar defects by transvaginal ultrasound imaging. METHODS: Two hundred and eighty-seven women underwent transvaginal ultrasound examination 6-9 months after delivery: 108 had undergone one Cesarean section, 43 had had two Cesarea

Popular Abstract in Swedish Att vatten är en otroligt viktig vätska för allt liv på jorden känner de flesta till; exempelvis består över hälften av människokroppen av vatten, och 70 procent av jordens yta är täckt av det. Att just denna till synes enkla kemikalie, vars molekyler består av två väteatomer och en syreatom, har en sådan unik betydelse är ingen slump, utan beror på att vatten har en raFluids composed of dipolar molecules are ubiquitous in nature, with water being the most prominent example. Due to their great importance and large complexity, a basic scientific understanding of the structure and thermodynamics of polar fluids is essential. In this thesis, simple polar model fluids are investigated with the aim of adding a bit to this understanding. In particular, the topics addr

Background: Assessing and evaluating health care is important, and an abundance of instruments are developed in different languages. Translating existing, validated instruments is demanding and calls for adherence to protocol. Purpose: The purpose of this study was to translate and culturally adapt the FAMCARE-2 scale for use in Sweden. Methods: Traditional back-translation and the decentering sta

Exogenous soluble human alpha 3 noncollagenous (NC1) domain of collagen IV inhibits angiogenesis and tumor growth. These biological functions are attributed to the binding of alpha 3NC1 to integrin alpha v beta 3. However, in some tumor cells that express integrin alpha v beta 3, the alpha 3NC1 domain does not inhibit proliferation, suggesting that integrin alpha v beta 3 expression is not suffici

The peak-to-valley (PTV) method was investigated experimentally comparing PTV ratios for three HPGe detectors, with complementary Monte Carlo simulations of scatter in air for larger source-detector distances. The measured PTV ratios for 137Cs in air were similar for three different detectors for incident angles between 0 and 90°. The study indicated that the PTV method can differentiate between s

PURPOSE:: To investigate how patients with neovascular age-related macular degeneration treated with ranibizumab or bevacizumab respond to treatment in daily clinical practice. METHODS:: Data from the Swedish Macula Register on the treatment received by 3,912 patients during 2011 to 2014 is reported. Patientsʼ characteristics at the first visit, visual acuity, number of injections, and reason for

The purpose of this study was to derive calibration coefficients (in terms of cps kBq-1) and minimum detectable activities, MDA, (in terms of kBq and corresponding dose rate) for the dual head gamma camera part of an SPECT/CT-instrument when used for in vivo internal contamination measurements in radiation emergency situations. A cylindrical-conical PMMA phantom with diameters in the range of 7-30

Abstract The aim of this study was to evaluate a general school-based 1-year exercise intervention program in a population-based cohort of girls at Tanner stage I. Fifty-three girls aged 7–9 years were included. The school curriculum-based exercise intervention program included 40 minutes/school day. Fifty healthy age-matched girls assigned to the general school curriculum of 60 minutes physical a

We revised the hip (6 stems and 5 sockets) with impacted morselized allografts and cement in 6 patients. We followed prosthetic migration by roentgen radiostereometric analysis (RSA) every 7th day for 6 weeks after the first (index) examination performed on the first postoperative day before mobilization. Most of the migration occurred during the first 2 weeks. In most cases more than half of the

Europeiska Kommissionens riktlinjer för statligt stöd till miljöskydd och energi fungerar som rådgivande dokument till Medlemsstater när de utvecklar statliga stödåtgärder för miljöskydd och energi. Kommissionen har lagt till förslag att utvidga riktlinjernas räckvidd för att implementera den europeiska gröna given som fastställer målet för Europa att bli klimatneutralt 2050. Investeringsplanen inThe European Commission’s guidelines on environmental protection and energy provide guidance for Member States to develop State aid schemes for certain environmental and energy measures. The Commission has proposed to broaden these guidelines in order to conform with the European Green Deal’s goal of achieving climate neutrality by 2050. The European Green Deal Investment Plan also plans to mobili

Despite the hegemonic status of global health governance that favors the high-income countries (HICs), global health diplomacy (GHD) as a critical tool to manage health is an understudied subject particularly in low- and middle-income countries (LMICs). This research illustrates how GHD is exercised in Indonesia by exploring the actors, their capacities, and the surrounding context. The aim of the

BACKGROUND: The locoregional failure rate remains high in advanced cervical carcinoma. Chemotherapy (CT) was added to radiotherapy (RT) in order to increase disease control and to improve 5-year survival.METHODS: CT + RT included cisplatin administered 100mg/m2, d.1 plus 5-fluorouracil 1000 mg/m2 D.1 to 5, ci (120 hrs), q every 3rd week for 3 cycles, followed by RT. RT included external beam irrad

Episodic memories typically comprise multiple elements. A defining characteristic of episodic retrieval is holistic recollection, i.e., comprehensive recall of the elements a memorized event encompasses. A recent study implicated activity in the human hippocampus with holistic recollection of multi-element events based on cues (Horner et al., 2015). Here, we obtained ultra-high resolution function

Intranasal oxytocin (OT) has previously been found to increase spirituality, an effect moderated by OT-related genotypes. This pre-registered study sought to conceptually replicate and extend those findings. Using a single dose of intranasal OT vs placebo (PL), we investigated experimental treatment effects, and moderation by OT-related genotypes on spirituality, mystical experiences, and the sens

Two low-power mm-wave voltage controlled oscillators (VCOs) designed in a 28-nm fully-depleted silicon-on-insulator (FD-SOI) CMOS process are demonstrated, using a push-pull differential architecture. Measurement show that the first VCO has a 10.8% tuning rage centered at 30.3 GHz, and the second has a 8.9 % tuning range at 58.7 GHz. The 30 GHz VCO consumes 1.06 mW from a 1 V supply, and has a -11