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One important complication of patients with severe haemophilia A is the formation of inhibitory antibodies to factor VIII (FVIII). Immune tolerance induction (ITI) is the treatment of choice for patients with inhibitors, but this approach is successful in about 60% of patients. Treatment of acute bleeding in patients with inhibitors is one of the greatest challenges in haemophilia management and i
Using delayed-coincidence techniques we have measured the natural radiative lifetimes of several S and D states in Rb and Cs. The states were excited by a pulsed dye laser from the first P state, populated using an rf discharge lamp.
This article focuses on teachers’ and principals’ experiences of aggressive emails in home–school collaborations with parents. Semi-structured interviews with 31 teachers and principals from primary, lower and upper secondary schools in Sweden were conducted. Three categories were identified in the material which illuminate the phenomenon of cyberaggression towards principals and teachers from par
In the plant-based beverage industry, a residue called okara, is generated in large quantities in the liquid-solid separation step. Despite the high nutritional value of okara from soy and oat beverages with respect to fiber and protein content, these residues are generally discarded or used as animal feed or compost. It would be more sustainable to utilize okara for human consumption, however, th
Educational development initiatives in the form of short-lived, isolated pedagogical courses may at best change the thinking and practice of a few pioneers, and then perhaps only temporarily. It is only possible to successfully address the need that such initiatives are intended to meet if the impact is lasting and effects a cultural change locally at the university. In this study, we look beyond
The formation of a hybrid composite material consisted of polymer brushes and phenylboronic acid ligands on a macroporous cryogel is reported here for the first time for effective adsorption of glycoprotein and yeast cells. The surface area of the cryogel was increased by covalent immobilization of silica nanoparticles. Random copolymer brushes composed of N-isopropylacrylamide and glycidyl methac
Breast cancer is the most common cancer form among women in the Western world. Although treatment has improved during the last decades, there is still a significant proportion of the patients who are not cured. To further improve clinical outcome we need new treatment strategies, new prognostic markers, and new treatment predictive factors for personalized medicine.In this dissertation I have focu
In this paper we present a non-linear demand system for households' joint choice of number of trips and days to spend at a destination. The approach, which facilitates welfare analysis of exogenous policy and price changes, is used empirically to study the effects of an increased CO2 tax. In particular, we focus on the effect of including substitution between households choice of the number of tri
Fire models are used increasingly for fire safety assessment in nuclear power plants. Examples of these fire models are CFD models and zone models. When using these models it is important that they are sufficiently verified and validated. In Sweden the majority of fire safety consultants are using FDS, developed by NIST. The verification and validation of this package is intensively done for a num
Längs Kaledonidernas östra erosionsfront finns den världskända bly- och zinkfyndigheten vid Laisvall (totalt 64 miljoner ton bruten malm) och mineraliseringen vid Granberget samt flertalet mindre malmkroppar av impregnationstyp bestående av blyglans och zinkblände som kristalliserat i klastiska bergarter. I äldre litteratur har mineraliseringsprocesserna och tidsspannet för mineralisationen diskutThe eastern Caledonian erosional front hosts the world-class Pb-Zn deposit at Laisvall (64 Mt mined) and Granberget mineralization, northern Sweden, along with several other smaller, related types of deposits consisting of impregnation mineralization of galena and sphalerite in clastic host rocks. Previous work have discussed the nature of the ore-forming processes and constraints for the timing o
Pålning är en typ av grundläggning lämplig för att grundlägga broar vid svaga markförhållanden. Att manuellt utforma en pålgrupp är en iterativ, tidskrävande process där snittkrafterna i pålarna måste verifieras för ett stort antal lastfall. Efter installationen kan pålarna dessutom ha nya positioner och kapaciteten måste verifieras igen. I detta projekt utvecklades en mjukvara för att automatiserFor bridges in weak ground conditions, piling is an appropriate type of foundation. To manually arrange the piles in a pile group is an iterative, time consuming process where the section forces in the piles must be verified for a large number of load cases. In addition, after installation, piles may have new positions and the capacity must be re-verified. In this thesis, a software was developed
Introduction: In former studies from North America early Do-Not-Resuscitate orders (DNR orders) in patients with intracerebral haemorrhage (ICH) had negative prognostic impact on mortality. The influence of DNR orders on functional outcome and whether DNR orders are grounded on relevant patient characteristics is unknown. We aimed to determine the frequency and predictive factors of DNR-orders and
With his notion of original affirmation, Paul Ricoeur wishes to reinstate the primacy of being over nothingness, joy over anguish, and affirmation over negation. Having adopted the term from Jean Nabert, he draws from the tradition of French reflective philosophy to formulate his conception of the originally affirmative nature of existence. Ricoeur argues that positive values can be found in and t
This thesis evaluates the effect of Chinese Foreign direct investment (FDI) on exports and imports for the five African countries: Angola, Nigeria, South Africa, Zambia and Zimbabwe using the gravitational model. The gravitational model will analyze how both inward FDI investments and Chinese investments impact import and export by using a sample of 166 partner countries over the period 2003-2012.
Per- and polyfluoroalkyl substances (PFAS) include a large group of chemicals that has been used for many decades because of their mechanical and chemical stability. They owe these unique features due to the strong C-F bonds in their molecules. PFAS can be fully or partly fluorinated and the more fluorinated they get, the more persistent they become. They have been used in several industries such
