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The presence of iduronic acid in chondroitin/dermatan sulfate changes the properties of the polysaccharides, as it generates a more flexible chain with increased binding potentials. Iduronic acid in chondroitin/dermatan sulfate influences multiple cellular properties such as migration, proliferation, differentiation, angiogenesis and regulation of cytokine/growth factor activities. During patholog
Microsoft Word - Behavioral Terminal node_inftrastructure report 2021.docx Multipark infrastructure report form 2021 In vivo- terminal node Cecilia Lundberg 1. Short description of the infrastructure. The terminal room contains two set ups for perfusion of rodents and instruments for fresh dissection of brains. Furthermore, there are facilities to prepare solutions and weigh drugs as well as store
The Environmental Determinants of Diabetes in the Young (TEDDY) Study IMMUNOLOGY OF DIABETES V The Environmental Determinants of Diabetes in the Young (TEDDY) Study TEDDY Study Group The etiology of type 1 diabetes (T1D) remains unknown, but a growing body of evidence points to infectious agents and/or components of early childhood diet. The National Institutes of Health has established the TEDDY
https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_06_teddy_study_group_nyas_2008.pdf - 2026-05-28
Denna uppsats är en undersökning som syftar till att utreda Fi:s politiska strategier när de möter kritiken från de etablerade partierna i Malmös kommunfullmäktige. I uppsatsen förklaras kort om Feministiskt Initiativets (Fi) politiska partiprogram i Malmö stad under det senaste året. Utifrån tidigare/empiriska forskningar, kring kvinnoorganisationer, kommer denna undersökning att visa hur Fi:s po
Problem: Bemanningsbranschen har under de senaste åren ökat oerhört. Allt fler företag ser konsulter som ett alternativ till fasta anställningar. Nya marknadsdelar som exempelvis vården har blivit tillgängliga vilket gjort att bemanningsföretagen kunnat bredda sin verksamhet. I denna växande bransch finns behovet av en specifik företagskultur för de konsulter som inte fysiskt befinner sig på det k
Syftet med denna uppsats är att undersöka hur journalister på dags- och kvällstidningar i Sverige framställer Sverigedemokraterna under åren 2002, 2006 och 2010. Orsaken till att utreda hur Sverigedemokraterna har framställts ligger främst i mediernas omtalade makt som informationskälla, men också hur viktig journalistens roll anses i en demokrati, att denne ska presentera en övergripande informat
The development of cancer is driven by the accumulation of many oncogenesis-related genetic alterations and tumorigenesis is triggered by complex networks of involved genes rather than independent actions. To explore the epistasis existing among oncogenesis-related genes in lung cancer development, we conducted pairwise genetic interaction analyses among 35,031 SNPs from 2027 oncogenesis-related g
Diamond-Blackfan anemia (DBA) is a bone marrow failure syndrome caused by mutations in ribosomal protein genes. Pathogenic mechanisms are poorly understood but involve severely reduced proliferation of erythroid precursors. Because current DBA therapies are ineffective and associated with severe side effects, disease-specific therapies are urgently needed. We hypothesized that druggable molecular
Purpose To investigate multivoxel proton Magnetic Resonance Spectroscopy (1HMRS) biometrics for preoperative differentiation and prognosis of patients with brain metastases (MET), low-(LGG) and high grade glioma (HGG). Methods Thirty-five patients (15 HGG, 9 LGG and 11 MET) were included. Proton Magnetic Resonance Spectroscopy Imaging(1H-MRSI) data was assessed and neurochemical profiles for metab
Firefighters can be occupationally exposed to a wide range of airborne pollutants during fire-extinguishing operations. The overall study aim was to characterize occupational exposure to smoke for several groups of workers responding to fires, with specific aims to determine the correlations between exposure markers and to biologically assess their systemic exposure to polycyclic aromatic hydrocar
Vocal problems are common among workers in voice demanding occupations. For sustaining vocal health, it is important to find efficient ways to reduce strain on the voice at work. One way to do so is optimizing the room acoustics for communication. However, we do not know enough about what kind of room acoustic conditions that support voice and speech most efficiently, and if talkers of different a
Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) have yielded only limited insights, leaving the observed heritability of HF largely unexplained. We report results from a GWAS meta-analysis of HF comprising 47,309 cases and 930,014 controls. T
Background: It remains unclear whether heritable factors can contribute to risk stratification for ischemic stroke in patients with atrial fibrillation (AF). We examined whether having a sibling with ischemic stroke was associated with increased risk of ischemic stroke and mortality in patients with AF. Methods and Results: In this nationwide study of the Swedish population, patients with AF and t
Aims: In the present study, we aimed to evaluate the performance of machine learning (ML) models for identification of acute myocardial infarction (AMI) or death within 30 days among emergency department (ED) chest pain patients. Methods and results: Using data from 9519 consecutive ED chest pain patients, we created ML models based on logistic regression or artificial neural networks. Model input
Background Preeclampsia is considered a major cause of maternal and fetal morbidity and mortality. The aim of the present case-control study in Sweden was to assess the hypothesized association between low serum vitamin D concentrations in early pregnancy and the risk of developing preeclampsia since vitamin D may play a role in early placental development. Methods The study included 296 women dia
Stem cell transplantation can improve behavioral recovery after stroke in animal models but whether stem cell-derived neurons become functionally integrated into stroke-injured brain circuitry is poorly understood. Here we show that intracortically grafted human induced pluripotent stem (iPS) cell-derived cortical neurons send widespread axonal projections to both hemispheres of rats with ischemic
Genome wide association studies (GWAS) have mapped multiple independent cancer susceptibility loci to chr5p15.33. Here, we show that fine-mapping of pancreatic and testicular cancer GWAS within one of these loci (Region 2 in CLPTM1L) focuses the signal to nine highly correlated SNPs. Of these, rs36115365-C associated with increased pancreatic and testicular but decreased lung cancer and melanoma r
Heart failure (HF) is a major public health problem characterized by inability of the heart to maintain sufficient output of blood. The systematic characterization of circulating proteins across different stages of HF may provide pathophysiological insights and identify therapeutic targets. Here we report application of aptamer-based proteomics to identify proteins associated with prospective HF i
On-demand droplet generation from a continuously flowing stream of aqueous phase has profound applications in dropletbased microfluidics for rare event encapsulation studies. Here, we present acoustic relocation-based droplet generation from co-flowing immiscible fluids in an on-demand manner using bulk acoustic wave (BAW). After on-demand droplet generation, droplets are isolated using the same a
MASTER’S DISSERTATION AT ENGINEERING ACOUSTICS xpTVBA-5065 (2025-01) DEPARTMENT OF CONSTRUCTION SCIENCES | FACULTY OF ENGINEERING LTH | LUND UNIVERSITY DIVISION OF ENGINEERING ACOUSTICS Faculty of Engineering LTH, Lund University, Box 118, SE-221 00 Lund, Sweden • Tel: + 46 (0)46-222 73 70 • Fax: + 46 (0)46-222 44 20 • www.akustik.lth.se AKUSTISK UPPGRADERING AV ÅTERBRUKADE INNERVÄGGAR I KONTORSMI
https://www.akustik.lth.se/fileadmin/tekniskakustik/masterprojects/descriptions/xpTVBA5065.pdf - 2026-05-28
