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Autologous haematopoietic stem-cell transplantation versus bortezomib–melphalan–prednisone, with or without bortezomib–lenalidomide–dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study

Background: The emergence of highly active novel agents has led some to question the role of autologous haematopoietic stem-cell transplantation (HSCT) and subsequent consolidation therapy in newly diagnosed multiple myeloma. We therefore compared autologous HSCT with bortezomib–melphalan–prednisone (VMP) as intensification therapy, and bortezomib–lenalidomide–dexamethasone (VRD) consolidation the

Lunds kommuns klimatpolitiska råd : Rapport 2020

Lunds kommuns klimatpolitiska råd bildades hösten 2018 med uppdrag att utvärdera hur Lunds kommuns samlade politik är förenlig med de klimatmål somantagits av kommunfullmäktige. Rådet, som består av forskare från Lunds universitet (LU) och SLU Alnarp, har sammantaget en bred tvär- och mångvetenskaplig kompetens och en gedigen erfarenhet av samverkan med samhället. Samarbetet mellan Lunds kommun oc

EZH2 regulates the developmental timing of effectors of the pre-Antigen receptor checkpoints

The histone methyltransferase EZH2 is required for B and T cell development; however, the molecular mechanisms underlying this requirement remain elusive. In a murine model of lymphoid-specific EZH2 deficiency we found that EZH2 was required for proper development of adaptive, but not innate, lymphoid cells. In adaptive lymphoid cells EZH2 prevented the premature expression of Cdkn2a and the conse

Evaluation of Expression Level of Apolipoprotein M as a Diagnostic Marker for Primary Venous Thromboembolism

Recently, decreased levels of apolipoprotein M (ApoM) were shown to be associated with higher risk of recurrent venous thromboembolism (VTE) in male patients. However, the role of ApoM in primary VTE is unknown. We aimed in our study to analyze the plasma levels of ApoM in patients with VTE in order to evaluate the diagnostic importance of ApoM in primary VTE. A total of 357 patients with suspecte

Worse breast cancer prognosis in insulin treated diabetic patients - A population based registry study in Sweden

Background. Diabetes may be linked to incidence of different tumor diseases and prognosis through various mechanisms such as the disease itself, hyperglycemia, obesity and anti-diabetes therapy. Material and methods. The study includes all women with BC diagnosed in Sweden between 2000 through 2008 (n=54406). The women had no previous cancer diagnosis during the period of 1958-1999. Dates of birth

Cyclin-dependent kinase 8/19 inhibition suppresses osteoclastogenesis by downregulating RANK and promotes osteoblast mineralization and cancellous bone healing

Cyclin-dependent kinase 8 (CDK8) is a mediator complex-associated transcriptional regulator that acts depending on context and cell type. While primarily under investigation as potential cancer therapeutics, some inhibitors of CDK8—and its paralog CDK19—have been reported to affect the osteoblast lineage and bone formation. This study investigated the effects of two selective CDK8/19 inhibitors on

The Molecular Evolution of Castration-resistant Prostate Cancer

CONTEXT: Androgen deprivation therapy (ADT) is the backbone of treatment for advanced prostate cancer. However, castration-resistant prostate cancer (CRPC) nearly invariably develops through a range of different molecular mechanisms accompanied by progression to a more aggressive phenotype.OBJECTIVE: To understand the key molecular mechanisms leading to CRPC and the functional implications of this

Population-based incidence rate of inpatient and outpatient surgical procedures in a high-income country

Background: The WHO and the World Bank ask countries to report the national volume of surgery. This report describes these data for Sweden, a high-income country. Methods: In an 8-year population-based observational cohort study, all inpatient and outpatient care in the public and private sectors was detected in the Swedish National Patient Register and screened for the occurrence of surgery. The

Circulating cotinine concentrations and lung cancer risk in the Lung Cancer Cohort Consortium (LC3)

Background: Self-reported smoking is the principal measure used to assess lung cancer risk in epidemiological studies. We evaluated if circulating cotinine-a nicotine metabolite and biomarker of recent tobacco exposure-provides additional information on lung cancer risk. Methods: The study was conducted in the Lung Cancer Cohort Consortium (LC3) involving 20 prospective cohort studies. Pre-diagnos

Circulating insulin-like growth factor I in relation to melanoma risk in the European prospective investigation into cancer and nutrition

Insulin-like growth factor-I (IGF-I) regulates cell proliferation and apoptosis, and is thought to play a role in tumour development. Previous prospective studies have shown that higher circulating concentrations of IGF-I are associated with a higher risk of cancers at specific sites, including breast and prostate. No prospective study has examined the association between circulating IGF-I concent

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide association dataset and to empirically validate the PRSs in prospective studies. The development dataset comp

Statin use and breast cancer survival - A Swedish nationwide study

Background: A sizeable body of evidence suggests that statins can cease breast cancer progression and prevent breast cancer recurrence. The latest studies have, however, not been supportive of such clinically beneficial effects. These discrepancies may be explained by insufficient power. This considerably sized study investigates the association between both pre- and post-diagnostic statin use and

Handbok forskarprogrammet sv Jan-26

Handbok för forskarutbildningen Handbok för forskarutbildningen LUNDS UNIVERSITET | SOCIALHÖGSKOLAN HANDBOK FÖR FORSKARUTBILDNINGEN Handboken för forskarutbildning i socialt arbete riktar sig till doktorander, handledare och andra verksamma vid Socialhögskolans forskarutbildning. Men den kan även vara använd- bar för den som överväger att söka till utbildningen eller utför uppdrag åt institutionen

https://www.soch.lu.se/sites/soch.lu.se/files/2026-01/Handbok_forskarprogrammet_sv%20jan-26.pdf - 2026-06-22

Rostlangd MGeo-prefektval-250509

Förnamn Efternamn Beskrivning Hakim Abdi 156911 CEC - Forskare Anders Ahlström 156311 INES - Univlekt Cecilia Akselsson 156311 INES - Professor Helena Alexanderson 156350 Geologi - Professor Nikolaos Alexandridis 156911 CEC - Forskare Johanna Alkan Olsson 156911 CEC - Univlekt Carl Alwmark 156350 Geologi - Univlekt Sanna Alwmark 156350 Geologi - Univlekt, Biträdande Tobias Ambjörnsson 156911 CEC -

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2025-05/Rostlangd_MGeo-prefektval-250509.pdf - 2026-06-22

Asp kulturgeografi ekonomisk geografi 20201126

Allmän studieplan för utbildning på forskarnivå i kulturgeografi/ekonomisk geografi och geografi med kulturgeografisk inriktning Sida 1 av 11 Fakultetsstyrelsen ALLMÄN STUDIEPLAN KULTURGEOGRAFI/EKONOMISK GEOGRAFI Diarienummer U 2020/899 Datum 2020-11-26 Allmän studieplan för utbildning på forskarnivå i kulturgeografi/ekonomisk geografi och geografi med kulturgeografisk inriktning Allmän studieplan

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2020-12/asp_kulturgeografi_ekonomisk_geografi_20201126.pdf - 2026-06-22

Rapport - samverkan med det omgivande samhallet sfak 2020

Samhällsvetenskapliga fakultetens samverkan med det omgivande samhället Kartläggning och analys CHARLOTTE SIMONSSON & CHRISTOFFER HAHN SAMHÄLLSVETENSKAPLIGA FAKULTETEN | LUNDS UNIVERSITET 2 SAMVERKAN MED DET OMGIVANDE SAMHÄLLET Coverphoto by Petra Francke Layout and typesetting : Media-Tryck, Lund University Lund 2020 3SAMVERKAN MED DET OMGIVANDE SAMHÄLLET Innehåll Inledande om syfte och tillvägag

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2021-01/rapport_-_samverkan_med_det_omgivande_samhallet_sfak_2020.pdf - 2026-06-22

Saida från Baku, Azerbaijan berättar om sitt masterprogram

Masterstudenten Saida delar med sig av sina erfarenheter som student i Lund, vad som fick henne att ansöka till masterprogrammet, flytten till Lund, hur en typisk studievecka ser ut, vad hon tycker om sina studier och vilka planer hon har för framtiden.Master's student Saida shares her experiences as a student in Lund: what made her apply for the master's programme, moving to Lund, what a typical study week looks like, what she thinks about her studies, and her plans for the future.

Norunda arbetsplatsintroduktion inkl bilagor

Microsoft Word - Norunda Arbetsplatsintroduktion mätstation 2016-11-21 Att jobba på Norunda mätstation – arbetsplatsintroduktion – att delas ut till de som arbetar tillfälligt på mätstationen Norunda är en enhet inom Centrum för miljö- och klimatforskning, CEC vid Lunds universitet.  Ansvarsfrågor  Alla medarbetare skall på eget initiativ avhjälpa brister i arbetsmiljön och om befogenheterna inte

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/norunda_arbetsplatsintroduktion_inkl_bilagor.pdf - 2026-06-22

Schema iiiee mvet 2 vt19

Vecka Schema MVEC14 Miljövetenskap; reviderat 18 dec 2018 Industriell miljöekonomi för miljövetare VT 19 Fetstil markerar obligatoriska moment som måste genomföras för att få ut kursbetyget. Det mesta av undervisningen sker i Internationella miljöinstitutets lokaler på Tegnérsplatsen. Notera: Enskilda moment kan komma att behöva justeras tidsmässigt! Vecka Mån Tis Ons Tors Fre 4 21-25/1 13.15-16,

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_iiiee_mvet_2_vt19.pdf - 2026-06-22