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Given that FLT3 expression is highly restricted on lymphoid progenitors, it is possible that the established role of FLT3 in the regulation of B and T lymphopoiesis reflects its high expression and role in regulation of lymphoid-primed multipotent progenitors (LMPPs) or common lymphoid progenitors (CLPs). We generated a Flt3 conditional knock-out (Flt3fl/fl) mouse model to address the direct role

Lung cancer has several genetic associations identified within the major histocompatibility complex (MHC); although the basis for these associations remains elusive. Here, we analyze MHC genetic variation among 26,044 lung cancer patients and 20,836 controls densely genotyped across the MHC, using the Illumina Illumina OncoArray or Illumina 660W SNP microarray. We impute sequence variation in clas

Parvalbumin- (PV-) containing basket cells constitute perisomatic GABAergic inhibitory interneurons innervating principal cells at perisomatic area, a strategic location that allows them to efficiently control the output and synchronize oscillatory activity at gamma frequency (30–90 Hz) oscillations. This oscillatory activity can convert into higher frequency epileptiform activity, and therefore c

Background Whole-genome sequencing (WGS) of heart transplant recipient- and donor-derived cardiac biopsies may facilitate organ matching, graft failure prediction, and immunotolerance research. The objective of this study was to determine the feasibility of WGS based on formalin-fixed paraffin-embedded endomyocardial biopsies. Methods and results The study included serial donor- and recipient samp

BACKGROUND: Platelets are a critical element in coagulation and inflammation, and activated platelets are linked to cancer risk through diverse mechanisms. However, a causal relationship between platelets and risk of lung cancer remains unclear. METHODS: We performed single and combined multiple instrumental variable Mendelian randomization analysis by an inverse-weighted method, in addition to a

Tyrosine kinase inhibitors (TKIs) are highly effective for the treatment of chronic myeloid leukemia (CML), but very few patients are cured. The major drawbacks regarding TKIs are their low efficacy in eradicating the leukemic stem cells responsible for disease maintenance and relapse upon drug cessation. Herein, we performed ribonucleic acid sequencing of flow-sorted primitive (CD34+CD38low) and

Nanoplastics are emerging environmental contaminants that increasingly threaten soil ecosystems, yet their effects on microbial behavior remain poorly understood. This is mainly due to the lack of experimental tools capable of directly observing microbial dynamics in situ under realistic soil-like conditions. Here, we present a proof-of-concept system that enables real-time, high-throughput monito

The spectrum of frontotemporal dementia/amyotrophic lateral sclerosis (FTD/ALS) and Huntington disease (HD) are fatal neurodegenerative disorders with no major disease-modifying therapies. Recent work has shown that the hallmark pathological proteins TAR DNA binding protein of 43 kDa (TDP-43) in FTD/ALS and mutant huntingtin (mHTT) in HD may be interlinked. Furthermore, these disorders share early

Smart microscopy represents a paradigm shift in biological imaging, moving from passive observation tools to active collaborators in scientific inquiry. Enabled by advances in automation, computational power, and artificial intelligence, these systems are now capable of adaptive decision-making and real-time experimental control. Here, we introduce a theoretical framework that reconceptualises sma

The Big Butterfly Count reported its worst results in 14 years of monitoring UK species.

Debatt.indd 4 •A5 DN DEBATT Redaktör DN Debatt: Nils Öhman E-post: debatt@dn.se Telefon: 08-738 12 23 Twitter: @dndebatt Webb: DN.se/debatt FREDAG 30 MARS 2018 Regeringens nya förslag till nationell klimatanpassnings- strategi som lämnats som proposition till riksdagen den 8 mars i år tar fasta på den gällande ordningen i svensk styrning av vattenhantering – vilken vi anser bidrar till att skapa m

https://www.lucsus.lu.se/sites/lucsus.lu.se/files/pdf.pdf - 2026-05-09

200212. D€. schedule syllabus Doctoral School Agenda 2030 Digital Monies for a Sustainable Future The syllabus is preliminary and subject to changes till the course’s start. # Session Required readings Session focus Module 1: Setting the stage 1 Money today, theory and practice April 20, 13.00-16.00 Anders Ögren, Ester Barinaga, Paul Stankovski & Christian Gehrmann Readings: • Werner, R.2014. Can

https://www.sustainability.lu.se/sites/sustainability.lu.se/files/200212._deu._schedule_syllabus.pdf - 2026-05-09

Abstract Uppsatsen Fienden Inifrån granskar medierapporteringen kring Anders Breivik – gärningsmannen bakom terrordåden i Oslo den 22 juli 2011 med syftet att nå djupare insikt i hur media konstruerar fienden när denne kommer inifrån det egna samhället, samt vilka konsekvenser denna konstruktion får. Genom att undersöka 16 artiklar publicerade i Dagens Nyheter analyseras mediekonstruktionen av fi

Blad1 Signatur Namn Namn eng. Kommentar Typ av aktivitet AvslCer Avslutningsceremoni Graduation BasGrpArb Basgruppsarbete Student Group work BasGrpMöte Basgruppsmöte Student Group meeting BiblUnd Biblioteksundervisning Information literacy training Case Case Case Coachning Coachningsmöte Coaching Datorlabb Datorlaboration Computer Laboratory session Datorproj Datorprojekt Computer project DatorÖvn

https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2024-04/Alla%20undervisningstyper_2021-02-26.xlsx - 2026-05-09

Kursguide - Course Syllabus • • • • • Fastställande Kursplanen är fastställd av Samhällsvetenskapliga fakultetens styrelse 2009-05-12 att gälla från och med 2009-01-01. Allmänna uppgifter Kursen är en obligatorisk kurs inom kandidatprogrammet för Logistics Service Management och ges under andra terminen. Undervisningsspråk: Svenska Mål Efter genomgången kurs ska studenten ha goda grundkunskaper om

https://www.ses.lu.se/sites/ses.lu.se/files/vt15-kp-smla03-2019-05-12.pdf - 2026-05-09

Kursguide - Course Syllabus • • • • • • • Fastställande Kursplanen är fastställd av Naturvetenskapliga fakultetens utbildningsnämnd 2013- 01-09 att gälla från och med 2013-01-09, vårterminen 2013. Allmänna uppgifter Kursen är en obligatorisk kurs på grundnivå för det naturvetenskapliga kandidatprogrammet, inriktning meteorologi, vid Lunds universitet. Kursen ges även som fristående kurs. Kursen ge

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/ngea16_kursplan.pdf - 2026-05-09