Filtyp
The x2 glycosphingolipid is expressed on erythrocytes from individuals of all common blood group phenotypes and elevated on cells of the rare P/P1/P(k)-negative p blood group phenotype. Globoside or P antigen is synthesized by UDP-N-acetylgalactosamine:globotriaosylceramide 3-β-N-acetylgalactosaminyltransferase encoded by B3GALNT1. It is the most abundant non-acid glycosphingolipid on erythrocytes
Initial viral decay rate may be useful when comparing the relative potency of antiretroviral regimens. Two hundred twenty-seven ART-naive patients were randomized to receive efavirenz (EFV) (n=74), lopinavir/ritonavir (LPV/r) (n=77), or atazanavir/ritonavir (ATV/r) (n=79) in combination with two NRTIs. The most frequently used NRTI combinations in the EFV and ATV/r groups were the nonthymidine ana
ObjectivesUncertainty among healthcare providers about patients’ ability to make care decisions is a barrier to shared decision-making. We aimed to assess the self-reported decision-making ability of patients with cancer at the end of life.MethodsData from 11 countries of adults with a limited life expectancy and cancer as the primary diagnosis were used. Participants completed a questionnaire, in
Background and aims: Gallstone disease during pregnancy can have varying consequences, from mild to severe and even life-threatening. The aim was to investigate how gallstone intervention during pregnancy impacts pregnancy, delivery and the newborn child. Methods: Pregnant patients 18–45 years identified from the Swedish National Register for Gallstone Surgery and Endoscopic Retrograde Cholangiopa
Objective. In patients with axial spondyloarthritis (axSpA) initiating secukinumab (SEC), we aimed to identify baseline (treatment start) predictors of achieving low disease activity (LDA) after 6 months, as measured by the Axial Spondyloarthritis Disease Activity Score using C-reactive protein (ASDAS-CRP) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), as well as treatment contin
Much scholarship has critiqued the fact that non-governmental organisations (NGOs), as a result of global neoliberalism and consequential state retreat, have become private service providers of children’s protection rights. But how can we explain the situation when neoliberal states also undergo autocratisation and take back service provision from NGOs, while at the same time preserving the privat
Pediatric cancers exhibit complex evolutionary dynamics driven by genetic instability, clonal selection, epigenetic reprogramming, and microenvironmental interactions. Tumor evolution is typically characterized by branching phylogenies, where subclones with unique genetic profiles emerge at different locations and time points. Partly as a result of this diversity, advanced cancers often develop re
Democratic resilience has emerged as a central theme in academic debates in response to growing threats to contemporary democracies, yet little attention has been paid to resilience capacity to external stressors. This article conceptualises electoral integrity as a key democratic resilience capacity and examines how central actors in the Swedish electoral administration make sense of, and navigat
In Acoustofluidics, sound pressure waves can cause a force field on the liquid in a microfluidic channel. The forces depend on density and compressibility of the medium as well as the pressure and velocity amplitude of the sound. The forces lead to a steady flow in the bulk of the fluid, namely acoustic streaming. If a localized change in temperature introduces a gradient in compressibility and de
The very high spin behaviour of nuclei with ∼ 10 particles outside the 146Gd core are studied. Our method of calculation, which is based on the cranked Nilsson-Strutinsky formalism, makes possible to follow individual configurations as functions of spin. We concentrate on 158Er and 154Dy which nuclei become oblate with rotation around the symmetry axes for I = 40-50. It is found that most such obl
The low-spin features of odd-mass nuclei in the Z∼62, N∼90 region, for which stable octupole deformations has been previously suggested, are studied without introducing the static intrinsic reflection asymmetry (SIRA). Calculations using a Woods-Saxon potential and taking into account the Coriolis mixing show that most properties can be described in this approximation. Furthermore, the calculated
Introduction: Infection remains the most common treatment-related toxicity of childhood ALL, emphasizing the need to identify patients at risk and to tailor treatment strategies accordingly. Aims: The primary aim was to compare infectious toxicity during early treatment for childhood ALL following the ALLTogether and NOPHO ALL-2008 (ALL-2008) protocols, and second, to identify risk factors for inf
Mapping spatial variability of bioavailable strontium isotopes (87Sr/86Sr) is fundamental to robust analyses of prehistoric human and animal mobility and provenance based on strontium isotope data. A key challenge is how to construct and extrapolate a baseline for specific landscapes to enable meaningful correlation with high-resolution archaeological data. This study presents a regional high-reso
Aim: This study evaluates the health effects of plant-based dairy alternatives in healthy individuals and those with Inflammatory Bowel Disease (IBD). Specifically, it investigates whether replacing one daily meal with a plant-based alternative has a positive impact on intestinal microbiota composition and gut health. It also investigates whether the effect of probiotic bacteria in yogurt depends
Gastrointestinal (GI) interventional endoscopy has evolved into a cornerstone of modern gastroenterology, offering minimally invasive solutions for complex conditions. However, these procedures are not without risk, particularly with respect to post-procedural infections. While rare, such infections can have significant clinical consequences and are increasingly recognized as a public health conce
Strengths and limitations of the neurosphere culture system The Neurosphere Culture System Various methods with slight variations in protocol exist for establishing and expanding neurosphere cultures. Generally, neurospheres are derived from a single-cell suspension of neural stem and progenitor cells isolated from the adult or fetal central nervous system (CNS), but neurosphere cultures can also
This paper explores the rapid digitalization of the economy, focusing on the rise of platform and influencer economies, and examines their impact on place branding and clusters within rural regional development. Our study demonstrates how influencers in a rural industrial cluster become key figures in regional place branding by merging their digital identities with the natural resources they promo
After the wider deglaciation of Northern Europe, pioneer reindeer populations started to move into southern Scandinavia; however, this process is poorly understood. In this paper we aim to reconstruct dispersal processes of reindeer into southern and western Sweden from the Late Palaeolithic through to the Early Mesolithic, when reindeer disappear from the record. Has presence of reindeer in south
