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OBJECTIVE: To investigate changes in regional blood flows (RBF) and vascular porosity during the early phase of the autologous collagen II induced arthritis model (CIA) in rats and the possible influence of indomethacin and nitric oxide (NO) synthase on these variables. METHODS: RBF was measured with the microsphere method and vascular porosity by determination of extravasation of radiolabeled alb

Attenuated total reflectance FTIR spectroscopy was used to characterize Al(III)-acetate complexation at 25 degrees C, in homogeneous aqueous solution and at the water-aluminum hydroxide interface. The data collected in aqueous solution, at [Al](tot) = 0.080 M, [OAc](tot) = 0.040 M, and pH < 4.3, indicate the presence of only one dominating complex which, by spectral analysis, is shown not to invol

Studies were performed in guinea pigs to elucidate alterations in endogenous uterine norepinephrine (NE) levels and changes in the contractile response to exogenous NE following local sympathetic denervation, oophorectomy, or treatment with sex steroids. Both in intact and oophorectomized animals the myometrial NE concentration was reduced after sex steroid treatment (0.5 microgram 17-beta-estradi

objectives To assess effects of GH replacement therapy on cardiac structure and function, exercise capacity as well as serum lipids in elderly patients with GH deficiency (GHD). patients and methods Thirty-one patients (six females, 25 males), aged 60-79 years (mean 68 years) with GHD on stable cortisone and thyroxine substitution were studied. All men with gonadotropin deficiency had testosteron

To cite this article: Schlehofer B, Siegmund B, Linseisen J, Schüz J, Rohrmann S, Becker S, Michaud D, Melin B, Bas Bueno-de-Mesquita H, Peeters PHM, Vineis P, Tjonneland A, Olsen A, Overvad K, Romieu I, Boeing H, Aleksandrova K, Trichopoulou A, Bamia C, Lagiou P, Sacerdote C, Palli D, Panico S, Sieri S, Tumino R, Sanchez M-J, Rodriguez L, Dorronsoro M, Duell EJ, Chirlaque M-D, Barricarte A, Borgq

OBJECTIVE: To examine how different scoring models for a diet quality index influence associations with mortality outcomes. DESIGN: A study within the Malmö Diet and Cancer cohort. Food and nutrient intakes were estimated using a diet history method. The index included six components: SFA, PUFA, fish and shellfish, fibre, fruit and vegetables, and sucrose. Component scores were assigned using pre

The objective was to study obesity and insulin resistance in relation to leisure time physical activity (LTPA) and occupational physical activity (OPA) in a Swedish population, with particular focus on sex differences. Using a cross-sectional design, waist circumference, body mass index (BMI), glucose/insulin metabolism, blood pressure, heart rate, self-reported education, smoking, alcohol consump

Substitution of carbohydrates with fat in a diet for type 2 diabetes patients is still debated.

The gain profile of a quantum cascade laser is strongly influenced by the lifetime of the carriers in the upper and lower laser state. The quantitative description of gain within the concept of nonequilibrium Green's functions allows for a detailed understanding of various features affecting the gain spectrum: Compensation effects between scattering processes in the upper and lower laser level, re

Popular Abstract in Swedish I en komponent som utsätts för upprepande på- och avlastningar, d.v.s. cyklisk belastning, kan defekter i form av sprickor initieras och börja växa. Detta fenomen kallas utmattning och kan leda till haveri med potentiellt katastrofala följder. Det är därför viktigt att förstå fenomenen som ligger bakom utmattning och att ha tillförlitliga modeller för att förutsäga livsUnderstanding of the growth of fatigue cracks is of utmost importance since such growth often has a profound influence on the life of components subjected to cyclic loading. Thus, reliable fatigue life models enable a more efficient use of materials and improve the performance and efficiency in many applications. This thesis deals with the growth of fatigue cracks subjected to high load amplitude

Motor disturbances and disturbed self-recognition are common features that affect mobility in persons with schizophrenia spectrum disorder and bipolar disorder. Physiotherapists in Scandinavia assess and treat movement difficulties in persons with severe mental illness. The Body Awareness Scale Movement Quality and Experience (BAS MQ-E) is a new and shortened version of the commonly used Body Awar

The quality of spatial analysis is highly dependent on the geo-referencing quality and the definition of the geographic context variables used. However, such information is seldom considered in historical demographic and epidemiological research that includes the geographic context. We investigate a suitable geographic level for geocoding of the population and definition of geographic context vari

This paper gives an overview of the approach of working methods at the Aedas R&D Computational Design and Research [CDR] Group. It first contextualizes research in architectural practice and tries to propose an explanation for the difficulties in implementing it; then explains the evolution of the groups' computing approach from bespoke to heuristic sets of lightweight applications. It conclud

There is an increasing need for new biomarkers to improve prediction of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D). We aimed to identify blood-based epigenetic biomarkers associated with incident CKD and develop a methylation risk score (MRS) predicting CKD in individuals with newly diagnosed T2D. DNA methylation was analyzed epigenome wide in blood from 487 individuals

X-ray ptychography provides the highest resolution non-destructive imaging at synchrotron radiation facilities, and the efficiency of this method is crucial for coping with limited experimental time. Recent advancements in multi-beam ptychography have enabled larger fields of view, but spatial resolution for large 3D samples remains constrained by their thickness, requiring consideration of multip

A continental-type glacial flood termed the Suwałki megafloods took place in NE Poland during the last glaciation and significantly transformed the proglacial area. This study aims, for the first time, to establish the chronology of this flood. Twenty-two sediment samples from two meltwater spillways were dated by optically stimulated luminescence. Sixteen ages from the flood megadunes are between

Oxygen-defective metal oxides like cerium oxides exhibit giant electrostriction and field-induced piezoelectricity due to a dynamic electrosteric interplay between oxygen defects, V O ⋅ ⋅ , and the fluorite lattice. While such mechanisms are generally attributed to oxygen vacancies, recent results also highlight that trapped cationic defects, Ce Ce ′ , i.e. small polarons, can contribute to the el