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Obesity and cardiometabolic disease often, but not always, coincide. Distinguishing subpopulations within which cardiometabolic risk diverges from the risk expected for a given body mass index (BMI) may facilitate precision prevention of cardiometabolic diseases. Accordingly, we performed unsupervised clustering in four European population-based cohorts (N ≈ 173,000). We detected five discordant p
Globally we are facing a complex web of grand challenges that are impacting the lived environment, our development pathways, and wider quality of life. Urban environments serve as a key context around which these grand challenges are not only experienced while also providing multiple opportunities to reduce environmental impacts and resource consumption; improve health outcomes; eradicate poverty;
This article applies an agenda-setting approach to the impact of New Public Management on health-care reform in Sweden and Finland (1993–2016). A system-level view of agenda setting and New Public Management implementation is used to order the historical data derived from literature reviews of each health reform process. New Public Management is viewed as a hybrid concept rooted in the search for
Effects of various heating temperatures (124, 129, 134, 140 or 143 °C) and holding times (1 and 4 s) on milk quality using direct and indirect heating systems at pilot scale were investigated. Vitamin degradation was observed for both direct and indirect heating and the degradation increased with increasing temperature and holding time, however, no difference could be seen between heating systems.
We summarise our work on male mating behaviour in the tropical butterfly Bicyclus anynana, responding to the commentary provided by Nieberding and Holveck. We acknowledge that our laboratory studies are not free of shortcomings and potential caveats, though we attempted to address or highlight these within each paper. The concerns raised seem to stem mainly from different notions with respect to t
Phosphorylation of 6‐chloropurine riboside with phosphorus oxychloride and phosphorus trichloride gave a mixture of the two isomers, 6‐chloropurine‐riboside 2′,5′‐bisphosphate and 6‐chloropurine‐riboside 3′,5′‐bisphosphate. Reaction with 1,6‐diaminohexane followed by resolution of the isomeric mixture on a Dowex 1‐X2 column yielded N6‐(6‐aminohexyl)‐adenosine 2′,5′‐bisphosphate and N6‐(6‐amin
Previous research notes difficulties in functioning and low quality of life (QoL) among transition-age youth on the autism spectrum, and poor mental health may contribute to these difficulties. This study examined the role of autism symptom severity and mental health problems on self-reported functioning and QoL in treatment-seeking transition-age autistic youth. The study included 140 autistic yo
The study is motivated by scarce studies examining ethics of international development solutions. Moreover it is common for the field to investigate minorities’, i.e., direct beneficiaries’, or international development field professionals’ views, when the general public perspectives are rarely present in the research. However, everyday citizens who contribute to the field through taxes and donati
The fashion industry has been criticized for its significant negative environmental and labor rights impacts. In response, some fashion brands are now seeking to address these concerns by integrating ethical values into their operations and forming alliances with consumers to promote ethical consumption. While they have constructed ethical values and aim to communicate them to their consumers, the
Association studies were carried out in a sample of 86 patients from Sweden who had survived a myocardial infarction (MI) at a young age and 93 age-matched healthy individuals, to compare the impact of polymorphisms at the apolipoprotein (apo) AI-CIII-AIV gene cluster on among-individual differences in plasma lipid and lipoprotein traits, the five high density lipoprotein (HDL) subclasses (2b to 3
The age-adjusted incidence of multiple myeloma (MM) is 2-fold higher in African Americans than in whites. A few small studies have reported a higher prevalence of monoclonal gammopathy of undetermined significance (MGUS) in African Americans versus whites. Etiologic factors for MGUS and determinants for transformation of MGUS to MM are unknown. We quantified the prevalence of MGUS and subsequent r
Two oligonucleotide primers were used for selective enzymatic amplification of a DNA segment encoding a major portion of the first constant region domain (CH1) of the human IgG1 heavy chain. The selective amplification was confirmed by use of subclass-specific oligonucleotide probes. Two 15-mer oligonucleotides, hybridizing with the alleles for the allotypes G1m(f) and (z), respectively, could the
OBJECTIVE: To explore the utility of cluster analysis in defining complex dietary exposures, separately with two types of variables. DESIGN:: A modified diet history method, combining a 7-day menu book and a 168-item questionnaire, assessed dietary habits. A standardized questionnaire collected information on sociodemographics, lifestyle and health history. Anthropometric information was obtained
Principen jura novit curia är en central och vedertagen princip i svensk processrätt och tillämpas i domstolsprocessen. Principens relevans och tillämpning i skiljeförfarande är dock inte lika självklar mot bakgrund av skiljeförfarandets syften och bakomliggande principer. Frågan om en skiljenämnd kan, bör eller ska tillämpa principen jura novit curia på motsvarande sätt som i domstolsprocessen akThe principle of jura novit curia is a central and well-established tenet in Swedish procedural law, applied within court proceedings. However, its relevance and application in arbitration is not as clear, given the purposes and underlying principles of arbitration. The question of whether an arbitral tribunal can, should, or must apply the principle of jura novit curia in the same manner as in co
