Sökresultat

Popular Abstract in Swedish Övergripande syfte Syftet med avhandlingen var att utvärdera hur en förenklad metod för diagnostisering av blodproppar i benets djupa ådror (djup ventrombos (DVT)) fungerar i svensk rutinsjukvård. Den förenklade metoden innebär användning av en strukturerad klinisk sannolikhetsbedömning tillsammans med ett blodprov (D-dimer test). Vi jämförde också vår D-dimermetod med The combination of pre-test clinical probability assessment and D-dimer test is now widely applied in the diagnostic process of DVT. The general objective of the present investigation was to validate these results in a Swedish routine emergency setting were the prevalence of the disease is high and were the clinical probability assessment was handled by many junior physicians. Furthermore, our aim

BACKGROUND: Animal studies indicate that some phthalate metabolites may harm female reproductive function. OBJECTIVES: We assessed the associations between exposure to phthalate metabolites and pregnancy loss. METHODS: Using a previously established cohort of couples planning their first pregnancy, we analyzed four primary and two oxidized secondary phthalate metabolites in urine samples collected

A functionally normal TP53 is essential to protect organisms from developing cancer. Somatic mutations in the gene represent one of the highest recurring perturbations in human tumours, including colorectal cancer (CRC). However, the variegated phenotype of wide spectrum of somatic mutations in TP53 and the complexity of the disease prevent a straight interpretation of the mutational analysis in t

Aims: TCF7L2 variants have been associated with type 2 diabetes, body mass index (BMI), and deficits in proinsulin processing and insulin secretion. Here we sought to test whether these effects were apparent in high-risk individuals and modify treatment responses. Methods: We examined the potential role of the TCF7L2 rs7903146 variant in predicting resistance to weight loss or a lack of improvemen

Ethnologists like to think of themselves as masters of the study of the everyday, but we still know surprising little how this mundane machinery works. Everyday life remains something of a black box, our understanding is still piecemeal and fragmented. This paper explores cohabitation and circulation of objects, affects and activities in the home - seen as a workshop where raw materials, raw feeli

Here, we report and investigate the genomic alterations of two novel cases of Non-Hodgkin Lymphoma (NHL) in children with Williams-Beuren syndrome (WBS), a multisystem disorder caused by 7q11.23 hemizygous deletion. Additionally, we report the case of a child with NHL and a somatic 7q11.23 deletion. Although the WBS critical region has not yet been identified as a susceptibility locus in NHL, it h

Background: There is an association between a greater adherence to a Mediterranean diet and a reduced risk of developing chronic diseases. However, it is not clear whether this dietary pattern may be protective also against the development of obesity. Objective: We assessed the association between the adherence to the Mediterranean dietary pattern (MDP), prospective weight change, and the incidenc

Science and Technology Studies (STS) projects often aim at understanding social problems and epistemic challenges in science and, more generally, in the technoscientific worlds we inhabit. However, it is often unclear if and how these projects can help address the problems they identify. Scholars such as Donna Haraway, John Law, and Karen Barad have argued that STS methods always interfere with th

Recovery of lost neurological function after stroke is limited and dependent on multiple mechanisms including inflammatory processes. Selective pharmacological modulation of inflammation might be a promising approach to improve stroke outcome. Methods: We used 1,1'-[1,4-phenylenebis(methylene)] bis[1,4,8,11-tetraazacyclotetradecane] (AMD3100), an antagonist to the C-X-C chemokine receptor type 4 (

Purpose - The purpose is to investigate how a retailer identifies critical network actors and gains their support when entering an emerging market. and to examine the role of a firm's relationships with different types of actors on the new market. Design/methodology/approach - The study is of an exploratory nature, and based on an inductive and qualitative research method. A case study of IKEA's e

In a population-based study on cobalamin status and incident fractures in elderly men (n = 790) with an average follow-up of 5.9 years, we found that low levels of metabolically active and total cobalamins predict incident fractures, independently of body mass index (BMI), bone mineral density (BMD), plasma total homocysteine (tHcy), and cystatin C. Cobalamin deficiency in elderlies may affect bon

The aim was to investigate how patients in a clinical setting, combining acute stroke care and rehabilitation, perceived the value and meaning attached to a commonly used instrumental occupation, namely "Brewing coffee and making an open-face cheese sandwich with sliced vegetable". Another aim was to validate the ValMO model, proposing that value and meaning are related phenomena. Upon performing

Background: Epidemiologic data and animal models suggest that, despite the predominant role of human papillomavirus infection, sex steroid hormones are also involved in the etiology of invasive cervical carcinoma (ICC). Methods: Ninety-nine ICC cases, 121 cervical intraepithelial neoplasia grade 3 (CIN3) cases and 2 control women matched with each case for center, age, menopausal status and blood

Understanding the processes generating fluctuations of natural populations lies at the very heart of academic ecology. It is also very important for applications such as fisheries management and pest control. We are interested in the effect of harvesting on population fluctuations and for that purpose we develop and analyze an age-structured model where recruitment is a stochastic process and the

This report gives a short introduction and overview of the research project conducted during the construction of the Limnologen-project in Växjö, Sweden. This multi-storey residential housing project has been documented in a number of sub-projects (vibrations and acoustics, sway, long term deformation, temperature and relative humidity in the structure, environmental impact of timber constructi

Biotic homogenization, a de facto symptom of a global biodiversity crisis, underscores the urgency of reforming water resources management to focus on the health and viability of ecosystems. Global population and economic growth, coupled with inadequate investment in maintenance of ecological systems, threaten to degrade environmental integrity and ecosystem services that support the global socioe