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Brattforsheden is a large glacifluvial deposit in southwestern Sweden and associated with it is one of Sweden's largest inland dune fields. Although the relative ages of the Brattforsheden deposits are well known, absolute ages from the area are few. In this study we have used optically stimulated luminescence (OSL), surface exposure (Be-10) and radiocarbon (C-14) dating to provide an absolute chr
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The aim of this study is to identify loci associated with circulating levels of Interleukin 8 (IL8). We investigated the associations of 121,445 single nucleotide polymorphisms (SNPs) from the Illumina 200K CardioMetabochip with IL8 levels in 1077 controls from the Stockholm Heart Epidemiology Program (SHEEP) study, using linear regression under an additive model of inheritance. Five SNPs (rs12075
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This study explores the worldwide spatial evolution of scientific knowledge production in biotechnology in the period 1986-2008. We employ new methodology that identifies new key topics in biotech on the basis of frequent use of title worlds in major biotech journals as an indication of new cognitive developments within this scientific field. Our analyses show that biotech is subject to a path- an
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Many manufacturing firms are expanding their global footprint to explore new opportunities for efficient and effective production. The strategic perspective on international manufacturing networks involves both the network level and the plant level. A key aspect is the relationship between the network and the role of plants. In this research, we investigate the relationship between the network and
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Psychoanalysis opens a variety of windows into understanding contemporary consumption and consumerism. The psychoanalytic theory of defence and the unconscious enables us to understand why commodities, from fast cars to luxury chocolate, so readily stand in to offer substitute gratification for deeper repressed desires and why the meaning of such commodities is liable to become mobile and unstable
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The main aim of this study is to compare how specific conditions in certain countries (in this case, the UK and Sweden) can stimulate or oblige householders to be more energy efficient, or can obstruct this. European goals for energy and emission reductions now constitute the main frame for long-term energy policy changes, but national governments develop and implement policy in contrasting ways a
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Recently, a hexanucleotide (GGGGCC) repeat expansion in the first intron of C9ORF72 was reported as the cause of chromosome 9p21-linked frontotemporal dementia-amyotrophic lateral sclerosis (FTD-ALS). We here report the prevalence of the expansion in a hospital-based cohort and associated clinical features indicating a wider clinical spectrum of C9ORF72 disease than previously described. We studie
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The RISING setup at the GSI-FRS facility was used to investigate the isomer and beta decays in N~Z~50 Cd, Ag and Pd isotopes. A preliminary analysis of the data has revealed new results on the Tz=1, 94Pd, 96Ag and 98Cd isotopes. In 94Pd a new high-spin isomer was observed, whilst in 96Ag 3 new isomeric states were identified, including core-excited states. In 98Cd a new high-energy isomeric γ-ray
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The importance of having correct structural descriptions is becoming ever clearer, not only in drug discovery research, but also in the development of new advanced materials. Here the key to optimizing properties lies in understanding the structure-property relationships. Without a correct description theoretical calculations will inevitably fail to describe and explain any experimental observatio
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Template-capped TiO2 nanostructures have been synthesized. In certain template conditions, TiO2 hexagons are found to form. These hexagonal structures can be effectively sensitized by fluorescein dye without any change in the protonation state of the dye. Bare TiO2 nanoparticles are not so useful for sensitization with dyes like fluorescein as they alter the dye protonation state. The novelty of t
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In this study, one-to-one tuition in higher music education (HME) was theorised as a culturally and historically grounded activity system consisting of relation- ships between musicians, instruments, music-making traditions and audiences. The ‘skills paradox’, as seen in the inherent conflict between musicians’ need for long-term artistic training and society’s demands for flexible knowledge produ
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Over the past decade, the chemistry of low-valent transition metal clusters has again come to the fore, primarily as a result of the development of nanochemistry and the realization that large clusters are on the cusp of the nano-domain. This perspective focuses on these recent developments in low-valent transition metal cluster chemistry, specifically looking at cluster-nanoparticles, the use of
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Terrestrial cosmogenic nuclide dating in combination with detailed landform mapping in the Kongsf-jordhallet area, NW Svalbard, have provided new insight on configuration, dynamics, and deglaciation of the Late Weichselian Kongsfjorden ice stream. The minimum Late Weichselian ice surface elevation in Kongsfjorden was >449 m a.s.l. indicating considerably thicker ice and a steeper surface gradient
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The use of quantitative performance measures to evaluate the productivity, impact and quality of research has spread to almost all parts of public R&D systems, including Big Science where traditional measures of technical reliability of instruments and user oversub- scription have been joined by publication counts to assess scientific productivity. But such performance assessment has been show
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The parasites Leshmania mexicana and Trypanosoma cruzi cause serious health problems, and few efficient treatments are available. Recently, the two benzochromenes pulchrol (1) and pulchral (2) were reported from the roots of Bourreria pulchra, and especially 1 but also 2 was found to be active towards the parasites. In this paper, we present a total synthesis of 1 and 2 to facilitate their biologi
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Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein that has been implicated in tumor-stroma interactions in pancreatic cancer. Here we evaluated the expression of SPARC during the progression of pancreatic cancer and its correlation with survival following curative intent surgery.
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This paper examines how the aging population affects the generosity of public long-term care (LTC) in Sweden. Theoretically, aging has a direct effect on LTC policy because the elderly become a more important voter group. However, concerns for other citizens may dampen the political importance of the elderly. Fixed effects regressions on municipality-level panel data for 1999-2007 suggest that LTC
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We present an experimental and theoretical study of the F-2(5/2) -> F-2(7/2) M1 transition in Ag-like W (W27+). The experiments employed the Shanghai permanent magnet electron beam ion trap, which has been developed especially for assisting spectroscopic diagnostics of edge plasmas for magnetic fusion devices. The theoretical value was obtained using the GRASP2K set of computer codes and included
