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The possibility of a “death from above” cause for biotic crises and extinction events is intriguing, to say the least, but such claims must be supported by reliable and reproducible data, not only impact diagnostic criteria, but also accurate and precise radioisotopic ages of the impact structures/events. To date, only one example of such an impact-related global extinction event is confirmed, at

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The meteoritic material falling on Earth is believed to derive from large break-up or cratering events in the asteroid belt. The flux of extraterrestrial material would then vary in accordance with the timing of such asteroid family-forming events. In order to validate this, we investigated marine sediments representing 15 time-windows in the Phanerozoic for content of micrometeoritic relict chrom

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Background In Scandinavia, people with a severe mental disorder have a reduced life expectancy of 15-20 years compared with the general public. Smoking is a major contributor, and smoke-free policies are increasingly adopted in psychiatric clinics around the world. We compared potential facilitators and barriers among staff and management, for the implementation of smoke-free psychiatric clinics.

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This paper examines virtual manifestations of “sad girls” on the media platform Tumblr. Here users write about their struggles with mental illness, revealing a set of shared experiences that encompass both psyche and body. Predominant narratives of what it means to be mentally ill are questioned, and alternative conceptualizations of the psyche are introduced. I argue that the sad girls legitimize

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Purpose: The aim of this paper is to explore whether and how external, political, financial and governance factors influence capital expenditure deviations in the Swedish municipal water and sewerage sector and to capture the consequences of municipal organisational fragmentation. Design/methodology/approach: Panel data analysis of 238 municipalities and 1,190 observations of capital expenditure d

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Early life adversities during childhood (such as maltreatment, abuse, neglect, or parental deprivation) may increase the vulnerability to cognitive disturbances and emotional disorders in both, adolescence and adulthood. Maternal separation (MS) is a widely used model to study stress-related changes in brain and behavior in rodents. In this study, we investigated the effect of MS (postnatal day 2–

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Microglial cells are affected in Alzheimer's disease (AD) and interact with amyloid-beta (Aβ) plaques. Apart from memory loss, depression is common in patients with AD. Electroconvulsive therapy (ECT) is an anti-depressive treatment that may stimulate microglia, induce neuroinflammation and alter the levels of soluble Aβ, but the effects of ECT on microglia and Aβ aggregation in AD are not known.

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Despite the many benefits of pulses, their consumption is still very low in many Western countries. One approach to solving this issue is to develop attractive pulse‐based foods, e.g., plant-based cheeses. This study aimed to assess the suitability of different types of pulse flour, from boiled and roasted yellow peas and faba beans, to develop plant‐based cheese analogues. Different stabilizer co

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To examine whether sequence-specific antibodies directed against serum amyloid A were useful in the demonstration and classification of amyloidosis, needle biopsy specimens from the kidneys of 152 cases with renal disorders were investigated using the avidin-biotin-peroxidase complex technique of immunohistochemistry. A distinct immunoreactivity of protein AA was seen in biopsies from all 42 indiv

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The use of cross-laminated timber (CLT) in multi-story buildings is increasing due to the potential of wood to reduce green house gas emissions and the high load-bearing capacity of CLT. Compression perpendicular to the grain (CPG) in CLT is an important design aspect, especially in multi-storied platform-type CLT buildings, where CPG stress develops in CLT floors due to loads from the roof or fro

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We examine socioecological drivers of nutrient overloading and eutrophication in the Chesapeake Bay associated with poultry production on the Delmarva Peninsula. We use a social metabolic analysis—rooted in a political-economy perspective—that highlights the interchange of matter and energy and the inextricable links within and between social and ecological systems, illuminating the social structu

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Purpose: This paper explores the idea of the prudent entrepreneurial self, through re-conceptualizing prudence into the domain of entrepreneurial education, to unite the two processes of becoming enterprising and entrepreneurial. It is argued that developing a capacity for prudence among graduates involves past, present and conjecture forms of knowledge that the authors find in the interplay betwe

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Introduction: Breast cancer is the most common malignancy affecting women. Although the prognosis generally is good, a substantial number of patients still suffer from relapse, emphasizing the need for novel treatments. Smac mimetics were developed to facilitate cell death by blocking inhibitor of apoptosis proteins (IAPs). It has been suggested that TNF-related apoptosis inducing ligand (TRAIL) c

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Background: Injury deaths constitute a major avoidable cause of death affecting life expectancy to a different degree in men and women. This study quantified the contributions of injury deaths to the gender gap in life expectancy (GGLE) and life disparity (GGLD) in nine Eastern Mediterranean Region (EMR) countries. Methods: We retrieved annual data on age-sex specific causes of death from the Worl

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Managing the impacts of land use change on ecosystem services is essential to secure human wellbeing; but is a task often complicated by landscape-scale spatial dynamics. In this study, we focus on one type of spatial dynamic: multi-site interactions (MSI), which we define to occur when a change in the supply or use of an ecosystem service at one site affects that service at a second site. In sear

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While insight into consumer brand engagement, experience, and identification is rapidly developing, little remains known regarding the association of these, and related, concepts, as therefore explored in this article. Drawing on social identity theory and service-dominant-logic, this study develops and tests a model that explores the effect of customers' brand credibility, -value congruence, and

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European Union challenges and crises of the past decade, including the Eurozone sovereign debt crisis, refugees, ethno-nationalist/Brexit movements, COVID-19, and Russian invasion of Ukraine are part of a planetary organic crisis (POC) of economy, society, ecology, conflict, and polity. The recognition of the symbiotic relationships between these challenges is crucial for moving from symptoms to c

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Reliable information on solar activity over the Holocene period is important to predict the Sun in the future and to understand the mechanism behind the Sun-climate linkage. Presently, there are discrepancies in the proxy data of solar activity due to reasons that are not yet understood. This leads to major uncertainties in Holocene solar reconstructions. This PhD project aims to improve the Holoc