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The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve well

Treatment of 2 equiv. of a mixture of the diphosphite cis, trans-1,3-(iPr2PO)2C6H 10 with [Pd(CO2CF3)2] and sequential addition of an excess of NaI gives the binuclear 16-atom ring chelate complex trans-[Pd2I4{cis-(iPr2PO) 2C6H10}2] (1) and the mononuclear complex cis-[PdI2{cis-(iPr2PO)2C 6H10}] (2) exclusively. NMR spectroscopy and X-ray crystallography have unambiguously determined the structure

We report the first detailed chemical abundance analysis of the exoplanet-hosting M-dwarf stars Kepler-138 and Kepler-186 from the analysis of high-resolution (R ∼ 22,500) H-band spectra from the SDSS-IV-APOGEE survey. Chemical abundances of 13 elements - C, O, Na, Mg, Al, Si, K, Ca, Ti, V, Cr, Mn, and Fe - are extracted from the APOGEE spectra of these early M-dwarfs

We describe the Sloan Digital Sky Survey IV (SDSS-IV), a project encompassing three major spectroscopic programs. The Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2) is observing hundreds of thousands of Milky Way stars at high resolution and high signal-to-noise ratios in the near-infrared. The Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey is obtaining spa

What do we need to know about our students to better provide for more equitable outcomes? Who will succeed depends on many factors, and student personality traits constitute one factor that has received less attention in the engagement and teaching literature. The aim of the present study is to add to discussions on teaching in higher education by exploring how students differ on personality trait

This book examines political, social, and economic interactions in highly interconnected areas, stretching from Europe to Eastern Europe, North Africa, the Middle East, and East Asia, labelled as Trans-Europe. The first part of the book focuses on the interests of several leading actors in Trans-Europe. The second part deals with the actions of national actors trying to compete with the EU influen

Late Permian mass extinction (LPME) research has focused primarily on Tethyan sections because it is believed that these successions are more complete than those from other localities, and provide a more comprehensive record of the largest, most devastating extinction event in Earth history. The Kisejin section, a previously undocumented mid-Tethyan, Upper Permian-Lower Triassic succession located

We investigate the viability of observing charged Higgs bosons ( H± ) produced in association with W bosons at the CERN large hadron collider, using the leptonic decay H+ → + ν τ and hadronic W decay, within different scenarios of the minimal supersymmetric standard model (MSSM) with both real and complex parameters. Performing a parton level study we show how the irreducible standard model backgr

Statins, commonly used to treat hypercholesterolemia, have also been proposed as anti-cancer agents. The identification of a predictive marker is essential. The 3-hydroxy-3-methylglutaryl-coenzyme-A reductase (HMGCR), which is inhibited by statins, might serve as such a marker. Thorough antibody validation was performed for four different HMGCR antibodies. Tumor expression of HMGCR (#AMAb90619, CL

Non-invasive imaging biomarkers (IBs) are warranted to enable improved diagnostics and follow-up monitoring of interstitial lung disease (ILD) including drug-induced ILD (DIILD). Of special interest are IB, which can characterize and differentiate acute inflammation from fibrosis. The aim of the present study was to evaluate a PET-tracer specific for Collagen-I, combined with multi-echo MRI, in a

In this article we present a case analysis of Sahar Khodayari’s transformation into a global injustice icon, the #BlueGirl, after she set herself ablaze outside a courthouse in Tehran, Iran, allegedly in protest against the ban on women entering football stadiums. We focus on the ways in which ‘pity’ was generated, mobilized, and transformed into indignation against the Iranian state by digital ac

This study shows that the production of industrial and commercial waste should form part of normal organisational practices. When asked about waste prevention, representatives of food, textile, electronics and construction companies in Sweden have difficulties highlighting concrete waste-prevention objectives, measures and outcomes. Instead, they highlight economic, technical, and organisational b

This article uses political psychology to understand emotions such as anger, hate, and passion in the Brexit debate in order to demonstrate the wider value of the political psychology of European integration. It uses five strands of political psychology to understand European integration, drawing on evidence from the Brexit debate. These strands are individual cognitive psychology, social psycholo

Homografts have long been used for right ventricular outflow tract (RVOT) reconstruction. Tissue banks struggle to meet the clinical demand of tissue, with insufficient donor availability and strict recommendations on tissue quality with high proportions of discards. This study analyzes the long-term outcome of patients receiving a homograft with small fenestrations of the cusps or other structura

It is currently unclear how amyloid-β and tau deposition are linked to changes in synaptic function and axonal structure over the course of Alzheimer's disease. Here, we assessed these relationships by measuring presynaptic (synaptosomal-associated protein 25, SNAP25; growth-associated protein 43, GAP43), postsynaptic (neurogranin, NRGN) and axonal (neurofilament light chain) markers in the CSF of

The atmospheres of close-in planets are strongly influenced by mass loss driven by the high-energy (X-ray and extreme ultraviolet, EUV) irradiation of the host star, particularly during the early stages of evolution. We recently developed a framework to exploit this connection and enable us to recover the past evolution of the stellar high-energy emission from the present-day properties of its pla