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BACKGROUND: Epidemiological studies have demonstrated an association between the degree of food processing in our diet and the risk of various chronic diseases. Much of this evidence is based on the international Nova classification system, which classifies food into four groups based on the type of processing: (1) Unprocessed and minimally processed foods, (2) Processed culinary ingredients, (3)
John-Paul Himka’s new book, Ukrainian Nationalists and the Holocaust: OUN and UPA’s Participation in the Destruction of Ukrainian Jewry, 1941-1944, represents a milestone in research on the complicity of the OUN-UPA in the Holocaust. Based on decades worth of research in dozens of archives around the world, Himka makes a well-documented and indisputable case for Ukrainian nationalist involvement i
A search is presented for the pair-production of heavy vector-like quarks in the lepton+jets final state using 140 fb−1 of proton–proton collisions at s=13 TeV collected with the ATLAS detector. The search is optimised for vector-like top-quarks (T) that decay into a W boson and a b-quark, with one W boson decaying leptonically and the other hadronically. Other vector-like quark flavours and decay
More than ever, Machine Learning (ML) as a subfield of Artificial Intelligence (AI) is on the rise and is finding its way into safety-critical software applications. However, when it comes to quality assurance (QA) and trustworthiness, integrating ML models into software comes with challenges that may not be apparent at first glance. The European Union (EU) aims to tackle this problem with new reg
A search for Higgs boson pair production via vector-boson fusion is performed in the Lorentz-boosted regime, where a Higgs boson candidate is reconstructed as a single large-radius jet, using 140 fb−1 of proton–proton collision data at s=13 TeV recorded by the ATLAS detector at the Large Hadron Collider. Only Higgs boson decays into bottom quark pairs are considered. The search is particularly sen
This chapter discusses the development of the ne bis in idem principle and assesses whether its judicial interpretation and application in the last years can be said to constitute a revolution for the enforcement of EU competition law. The analysis is divided into pre- and post-DMA litigation, starting from the creation of the principle of ne bis in idem in the interaction between the CJEU and ECt
OBJECTIVE: To explore trajectories of 12-week adherence to a digital education and exercise therapy for knee and hip osteoarthritis (OA), associations with baseline characteristics, and trajectories of patient-reported outcomes measures (PROMs) up to 1-year follow-up.DESIGN: Retrospective cohort (registry) study.METHODS: Weekly data on adherence (i.e. the percentage of completed activities (exerc
Background: Global supply chains are confronted with the challenge of ensuring on-time deliveries while simultaneously enhancing supply chain resilience. Conventional methods aim to address the complexities of modern supply chains, promoting the transition to intelligent and data-driven strategies. Methods: This research represents an innovative methodology for predicting the risk of late deliveri
Coastal environments, in particular heavily populated semi-enclosed marginal seas and coasts like the Baltic Sea region, are strongly affected by human activities. A multitude of human impacts, including climate change, affect the different compartments of the environment, and these effects interact with each other. As part of the Baltic Earth Assessment Reports (BEAR), we present an inventory and
This paper presents an LO frequency multiplier and phase shifter for the 28-GHz band, implemented in 28nm FD-SOI CMOS technology. The phase control is introduced in an injection-locked oscillator, followed by an injection-locked frequency tripler. The phase of the output signal is compared with that of the input signal using a phase detector based on third harmonic mixing, enabling automatic phase
National park agencies in Africa often lack incentives to maximize revenue, despite the decline in conservation subsidies from the State. We explore the potential of pricing policy to generate funds for extensive conservation. We estimate recreation demand by international tourists for a popular South African park, calculate the consumer surplus and find the revenue-maximizing entrance fee. Our re
A search for supersymmetry through the pair production of electroweakinos with mass splittings near the electroweak scale and decaying via on-shell W and Z bosons is presented for a three-lepton final state. The analyzed proton-proton collision data taken at a center-of-mass energy of s=13 TeV were collected between 2015 and 2018 by the ATLAS experiment at the Large Hadron Collider, corresponding
Myocardin-related transcription factors (MRTFs: myocardin/MYOCD, MRTF-A/MRTFA, and MRTF-B/MRTFB) suppress production of pro-inflammatory cytokines and chemokines in human smooth muscle cells (SMCs) through sequestration of RelA in the NF-κB complex, but additional mechanisms are likely involved. The cGAS-STING pathway is activated by double-stranded DNA in the cytosolic compartment and acts throug
The gut and oral microbiome is altered in people living with HIV (PLWH). While antiretroviral treatment (ART) is pivotal in restoring immune function in PLWH, several studies have identified an association between specific antiretrovirals, particularly integrase inhibitors (INSTI), and weight gain. In our study, we explored the differences in the oral and gut microbiota of PLWH under different ART
A search for a new heavy scalar or pseudo-scalar Higgs boson (H/A) produced in association with a pair of top quarks, with the Higgs boson decaying into a pair of top quarks (H/A → tt¯) is reported. The search targets a final state with exactly two leptons with same-sign electric charges or at least three leptons. The analysed dataset corresponds to an integrated luminosity of 139 fb −1 of proton–
More complex understanding of relationality in care networks around patients with life-limiting illness and their significant others is needed. This is the case not only because care is distributed unequally along gendered lines, but also because of the changing landscape of care in welfare states where families and communities are made more self-responsible. This study examines everyday experienc
On 12 July 2021 the World Health Organization (WHO) Expert Advisory Committee on Developing Global Standards for Governance and Oversight of Human Genome Editing published a set of reports entitled Human Genome Editing: A Framework for Governance and Recommendations. These reports provide valuable advice and recommendations on appropriate institutional, national and global governance mechanisms fo
