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Objective: To evaluate existing models for the origin of meta- and synchronous urothelial carcinomas in light of the accumulated genetic data. Methods: Published studies on the clonal origin and genetic relationships of syn- and metachronous tumors, genetic aberrations in normal and premalignant urothelial lesions, as well as histologic and genetic mapping studies of cystectomized bladder samples

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The structural organization of the gene for the human cysteine-proteinase inhibitor cystatin C was studied. Restriction-endonuclease digests of human genomic DNA hybridized with human cystatin C cDNA and genomic probes produced patterns consistent with a single cystatin C gene and, also, the presence of six closely related sequences in the human genome. A 30 kb restriction map covering the genomic

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Popular Abstract in Swedish Avhandlingen behandlar det nytestamentliga Judasbrevets texthistoria. Monografin inleds med en översikt av textforskningen på de Katolska Breven i allmänhet och Judasbrevet i synnerhet, från 1800-talet och fram till nutid. Mot bakgrund av det tecknade forskningsläget beskriver så författaren studiens upplägg och syfte, samt antyder några av resultaten. Det handlar främsThis study treats the textual tradition of the Epistle of Jude. After an introductory survey of earlier text-critical research, the two main purposes of this investigation are formulated: to gather and to analyze the complete textual evidence of the Epistle of Jude. The first task, to gather the evidence, involves the collation of all Greek continuous text MSS of the Epistle of Jude. The evidence

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The aim of this study was to determine the risk and burden of vertebral fractures judged as those coming to clinical attention and as morphometric fractures. Incidence and utility loss were computed from data from Malmo, Sweden. Clinical fractures accounted for 23% of all vertebral deformities in women and for 42% in men. The average 10-year fracture probability for morphometric fractures increase

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We present oxygen abundances for 72 F and G dwarf stars in the solarneighbourhood. Using the kinematics of the stars we divide them into twosub-samples with space velocities that are typical for the thick andthin disks, respectively. The metallicities of the stars range from[Fe/H] ≈ -0.9 to +0.4 and we use the derived oxygen abundances of thestars to: (1) perform a differential study of the oxygen

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The influence of personality factors on the appraisal of subjective quality of life in individuals with schizophrenia or schizoaffective disorder is not much investigated. The present study examined this relationship in a sample of 104 patients living in the community. The temperament and character inventory was used to assess personality and the Lancashire quality of life profile was used to asse

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In 1993-1998 the lichen flora of Stora Karlso and Lilla Karlso was surveyed. These two nearby islands are situated outside the west coast of Gotland, Sweden, in the Baltic Sea. In all, 355 species were found, including three lichenicolous fungi. Two species are new to Sweden, viz. Lepraria flavescens and Placynthium lismorense. Both were found on limestone. The number of species according to habit

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This paper investigates the outcome of ageing on taxes and hospitalisation of the elderly using panel data on 23 Swedish county councils 1980-1999. We test two hypotheses; whether a larger share of elderly has no negative effect on bed days per elderly person and no positive effect on tax rates. We reject the first hypothesis but fail to reject the second hypothesis. Further we cannot reject the h

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The ellipsoidally symmetric Buda-Lund hydrodynamic model describes naturally the transverse momentum and the pseudorapidity dependence of the elliptic flow in Au+Au collisions at roots(NN) = 130 and 200 GeV. The result confirms the indication of quark deconfinement in Au+Au collisions at RHIC, obtained from Buda-Lund hydro model fits to combined spectra and HBT radii of BRAHMS, PHOBOS, PHENIX and

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Reflux of equimolecular amounts 2-aminobenzylamine and isatins in acetic acid produced indolo[3,2-c]quinolin-6-ones in good yields. A proposed mechanism involving initial formation of a spiro compound is given. This isolable intermediate subsequently rearranges via a sequential isocyanate ring opening and a cyclisation process to a urea derivative which finally cyclized to the indolo[3,2-c]quinoli

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Pictures are typically better remembered than words, but explanations for this fact diverge. Some attribute picture superiority to more distinctive perceptual qualities, others to more efficient conceptual processing. In an effort to separate perceptual and conceptual factors, two groups were presented with mixed lists of pictures and words and were subsequently tested for recognition in either th

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Recent climate change has sparked an interest in the timing of biological events, which is a general problem in life-history evolution. Reproduction in many organisms breeding in seasonal environments, e. g. migratory birds, is dependent on the exploitation of a short but rich food supply. If the seasonal timing of the food peak advances owing to climate change, then one would expect the bird to t

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This study reassesses the occult philosophy of the British polymath John Dee (1527-1609). Focusing on his treatise Monas hieroglyphica (1564) and his notorious angelic conversations in the 1580s, it describes Dee’s philosophical career as a continuous search for a language which could yield knowledge of both nature and God. Situating Dee’s philosophy in the context of early modern “symbolic exeges

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Popular Abstract in Swedish Denna avhandling är en sammanläggningsavhandling som består av fyra artiklar inom arbetsmarknadsområdet. Den första artikeln behandlar en personalförstärkning till arbetsförmedlingen. Metoden har bestått i att jämföra tre arbetsförmedlingskontor som erhållit stora personalförstärkningar med tre kontor som inte fått någon personalförstärkning alls. Resultaten tyder på atThis thesis results from four research projects. The issues addressed in the projects are different types of labour market information problems. The purpose of the first article is to contribute to a better empirical under- standning of how an increase of staff at the Public Employment Service affects job seekers. In 1987, the Swedish Government decided to grant the Labour Market Administration ex

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In this study critical load functions and target load functions of nitrogen and sulphur deposition with respect to acidity and minimum base cation to aluminium ratio were calculated with the SAFE model using three different averaging strategies: (1) averaging based on current forest generation, (2) averaging based on next generation and (3) averaging based on the entire simulation period. From the