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BACKGROUND: ATOR-1017 (evunzekibart) is a human agonistic immunoglobulin G4 antibody targeting the costimulatory receptor 4-1BB (CD137). ATOR-1017 activates T cells and natural killer cells in the tumor environment, leading to immune-mediated tumor cell death.METHODS: In this first-in-human, multicenter, phase I study, ATOR-1017 was administered intravenously every 21 days as a monotherapy to pati

The Online Remote Behavioural Intervention for Tics (ORBIT) trial found that an internet-delivered, therapist-supported, and parent-assisted Exposure and Response Prevention (ERP) intervention reduced tic severity and improved clinical outcomes. This process evaluation aimed to explore mechanisms of impact and factors influencing efficacy. Participants were 112 children with a tic disorder and the

The recent phenomenon that has become known as the European refugee crisis is, in reality, a global problem. Accordingly, issues regarding refugee integration have become a central debate topic worldwide. In this paper, we examine how refugees use information and communication technology (ICT) in different regions across the world to understand how ICT supports their desperate journey to safety, t

Disease susceptibility mapping using spatial modeling techniques Author: Mohammadreza Rajabi Supervisors: Ali Mansourian , Petter Pilesjo GIS Center ,Department of Physical Geography and Ecosystem Science Lund University September, 2015 Disease susceptibility mapping using spatial modeling techniques ii Table of Contents 1- Introduction .............................................................

https://www.nateko.lu.se/sites/nateko.lu.se/files/mohammadreza-rajabi-first_year_seminar-17-08-2015-v4.pdf - 2026-05-23

In June 2024, the community of Roxborough Park, Colorado conducted a wildfire evacuation exercise (or drill for short) that was observed by a team of researchers. This collaborative effort involved residents, community organizers, first responders, emergency managers, and researchers. The drill aimed to test and refine evacuation protocols, communication strategies, and coordination among various

Popular Abstract in Swedish Hårfrisörer utsätts dagligen för en mängd kemikalier på arbetet. Många frisörer drabbas därför av luftvägsbesvär vilka ofta kan kopplas till hårblekningsmedel. Blekningsmedlen innehåller bland annat så kallade persulfater. Dessa tros vara en av huvudorsakerna till luftvägsbesvären. Flera studier har visat att persulfater kan ge symptom från luftvägarna såsom hösnuva ellHairdressers have an increased risk for developing airway symptoms e.g. asthma and rhinitis. Persulfate salts, which are oxidizing agents present in bleaching powder, are considered to be important causal agents for these symptoms. The underlying mechanisms are unclear and efficient tools for risk assessment and diagnosis are scarce. The general aim of this thesis was to measure proteomic changes,

The aim of this work was to investigate and quantify the effects of system noise, nodule location, anatomical noise and anatomical background on the detection of lung nodules in different regions of the chest x-ray. Simulated lung nodules of diameter 10 mm but with varying detail contrast were randomly positioned in four different kinds of images: 1) clinical images collected with a 200 speed CR s

We study inhomogeneous random graphs in the subcritical case. Among other results, we derive an exact formula for the size of the largest connected component scaled by logn, with n being the size of the graph. This generalizes a result for the "rank-1 case". We also investigate branching processes associated with these graphs. In particular, we discover that the same well-known equation for the su

The Kruppel-like protein ZNF224 is a co-factor of the Wilms' tumor 1 protein, WT1. We have previously shown that ZNF224 exerts a specific proapoptotic role in chronic myelogenous leukemia (CML) K562 cells and contributes to cytosine arabinoside-induced apoptosis, by modulating WT1-dependent transcription of apoptotic genes. Here we demonstrate that ZNF224 gene expression is down-regulated both in

In modern standard Swedish genitive is marked by -s, which, according to the standard analyses, is a phrasal clitic, viz. [mannen på gatan]s åsikt (man on street-s opinion). In dialects in parts of Småland, Halland, and Västergötland a variant on -a or -e, here called a-genitive, is used, primarily on proper names, viz. Erik-a bil (Erik-gen car) ‘Erik’s car’, a form that should be compared to the

Background. To study group B streptococcus (GBS) colonisation in parturients and infants in relation to obstetric outcome and to define serotypes and antibiotic resistance in GBS isolates acquired. Methods. A population-based, national cohort of parturients and their infants was investigated. During 1 calendar week in 2005 all women giving birth (n=1,754) were requested to participate in the study