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Traditional basal-bolus and closed-loop artificial pancreas therapy for type 1 diabetes mellitus were studied in the present work and novel insulin delivery profiles have been identified. Type 1 diabetes is a chronic condition resulting from autoimmune destruction of the pancreatic insulin producing β-cells. Inadequate insulin secretion prevents efficient glucose metabolism and is a serious health

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Collective action can be challenging in the governance of common pool resource. While social learning has the potential to facilitate negotiations and communications, power imbalance can still challenge the common pool resource (CPR) governance. In an attempt to study collective action in that context, I undertook a qualitative case study at the Cañete basin, Peru. The primary data was manly colle

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This thesis aims to describe and discuss the nomination processes within the political parties represented in the Swedish parliament today. It describes the guidelines for each party’s nomination process and discusses the placement and presentation of candidates on the ballot paper. The processes is analysed through earlier research on representation and strategic party politics in a multiparty-sy

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Climate migration is a global phenomenon that arises as a result of climate change. This thesis discusses the emergence of climate migration and what Sweden's contingency plan is for managing external climate migration in the future. The purpose of the thesis is to investigate Sweden's preventive work against international climate migration, and then the topic of climate justice and above

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Many cocoa farmers, despite their crucial role for the production of chocolate and other cocoa products that many consumers enjoy, struggle to earn a decent income and improve their livelihoods. This thesis analyses the impact of the Living Income Differential, a fixed 400$ price markup added to the per-tonne cocoa price, on the position of Ghanaian farmers in the global value chain. Based on the

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Slope failure has resulted in significant disruption to the Scottish road network in recent years and failure processes are widely considered to pose a very real risk to both infrastructure and road users. The manifestation of proposed regional climate variations could increase the hazard posed by landslide and debris flow activity within upland environments. It is therefore in the interests of de

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Placebo comparisons are increasingly being considered for randomised trials assessing the efficacy of surgical interventions. The aim of this Review is to provide a summary of knowledge on placebo controls in surgical trials. A placebo control is a complex type of comparison group in the surgical setting and, although powerful, presents many challenges. This Review outlines what a placebo control

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We report a case of congenital absence of the portal vein (CAPV) in an adult male who underwent resection for hepatocellular carcinoma. CAPV is a rare anomaly; only 29 cases, mostly in children, have been presented to date. An association between CAPV and cardiac abnormalities, polysplenia syndrome, skeletal abnormalities and liver tumors has been seen in children. To the best of our knowledge thi

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Background: Arthropod eyes have diversified during evolution to serve multiple needs, such as finding mates, hunting prey and navigating in complex surroundings under varying light conditions. This diversity is reflected in the optical apparatus, photoreceptors and neural circuits that underpin vision. Yet our ability to genetically manipulate the visual system to investigate its function is large

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Post-traumatic stress disorder (PTSD) impacts many veterans and active duty soldiers, but diagnosis can be problematic due to biases in self-disclosure of symptoms, stigma within military populations, and limitations identifying those at risk. Prior studies suggest that PTSD may be a systemic illness, affecting not just the brain, but the entire body. Therefore, disease signals likely span multipl

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A search is conducted for the electroweak pair production of a chargino and a neutralino pp→χ1±χ20, where the chargino decays into the lightest neutralino and a W boson, χ1±→χ10W±, while the neutralino decays into the lightest neutralino and a Standard Model-like 125 GeV Higgs boson, χ20→χ10h. Fully hadronic, semileptonic, diphoton, and multilepton (electrons, muons) final states with missing tran

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Background: Branch-duct intraductal papillary mucinous neoplasm (BD-IPMN) presents a clinical conundrum. Rigorous long-term surveillance or surgical resection is recommended. The economic consequences of the management have not been fully investigated. Methods: A Markov decision model compared 4 strategies for low-risk BD-IPMN: I = upfront total pancreatectomy, II = upfront partial pancreatectomy,

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The proportion of unpigmented coat on the trunk was determined from photographs of 38 German Simmental and 627 German Holstein bulls distributed over three generations. All 665 animals were members of 18 Holstein and 3 Simmental half-sib families. A Bayesian estimation of heritability yielded a posterior mean of 0.88 and a standard error of 0.08. A quantitative trait loci (QTL) scan over all chrom

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In this two part paper a theory is presented in which several control problems can be solved. The theory is applicable to a general class of linear multivariable systems where the measured output does not have to be equal to the controlled output or the state. The system may be affected by nonmeasurable disturbances. Only controllers which stabilize the system and have proper transfer functions ar

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The study of general linear multivariable systems, with possibly different controlled and measured outputs, is continued in this part of the paper. The structure matrices, defined in Part I, are used to solve the feedback realization problem. Feedback realizable transfer functions are then used to solve problems of "regulator type." It is shown that the solutions to problems like disturbance deeou

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The Poiseuille flow has been widely analyzed from analytical and experimental point of view with different approaches. Although the Lattice Boltzmann method (LBM) has proven to be a suitable tool for mimicking the fluid flow behavior not only for complex but also for simple geometries such as lid driven cavity and channel flow, the required computational size or characteristic length to obtain an