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Low expression of CysLT(1)R and high expression of CysLT(2)R mediate good prognosis in colorectal cancer

Colorectal cancer is the third most common cancer type in the western world. in search of new treatment possibilities, the inflammation mediators, know as cysteinyl leukotrienes (CysLTs), have been shown to regulate intestinal epithelial cell survival and proliferation via the CysLT(1)R, and cell differentiation via the CysLT(2)R. These results prompted us to investigate the significance of CysLT(

Aspects of beta cell and thyroid autoimmunity in children

Popular Abstract in Swedish Insulinberoende diabetes mellitus (IDDM = Typ 1 diabetes), och kronisk sköldkörtelinflammation - autoimmun thyreoidit (AIT) anses idag vara orsakade av att de hormonproducerande cellerna angrips av kroppens eget immunsystem (sk. autoimmunitet). När sjukdomen ger sig till känna kliniskt finnes antikroppar (sk. autoantikroppar) riktade mot cellkomponenter i det hormonprodThe two most common autoimmune endocrine diseases in children are autoimmune thyroiditis (AIT) and Type 1 (insulin-dependent) diabetes mellitus (IDDM). Autoantibodies (ab) can be found several years before clinical diagnosis in both diseases. The aims of this study were to investigate the prevalence of thyroid ab in children with IDDM and in children with allergic diseases; to study islet ab and t

Effect of androgen deprivation therapy on the expression of prostate cancer biomarkers MSMB and MSMB-binding protein CRISP3.

We have investigated the effects of short-term neoadjuvant and long-term androgen deprivation therapies (ADTs) on beta-microseminoprotein (MSMB) and cysteine-rich secretory protein-3 (CRISP3) expression in prostate cancer patients. We also studied if MSMB expression was related to genotype and epigenetic silencing. Using an Affymetrix cDNA microarray analysis, we investigated the expression of MSM

Implementation of an economic model to simulate manufacturing costs

An economic model describing manufacturing costs is implemented within the frame of a case study. The implemented economic model is developed to enable analyses of the cost items and parameters influencing the cost of a part or a batch and also to make simulations for the purpose of investigating the economic outcome of future development activities. The aim of the case study was to identify activ

Pre-treatment dosimetry for interstitial photodynamic therapy

A genetic algorithm for optimal placement of optical fibers in arbitrary geometries for interstitial photodynamic therapy has been developed. Based on calculated fiber positions, the diffuse light distribution is simulated by solving the diffusion equation by means of the finite element method and the treatment time is calculated. Utilizing an instrument for interstitial photodynamic therapy that

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma

Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous GWAS and a replication series, totalling 9974 MM cases and 247,556 controls of European ancestry. Collectively, these data provide evidence for six new MM risk loci, bringing the t

Decreased PGC1beta expression results in disrupted human erythroid differentiation, impaired hemoglobinization and cell cycle exit

Production of red blood cells relies on proper mitochondrial function, both for their increased energy demands during differentiation and for proper heme and iron homeostasis. Mutations in genes regulating mitochondrial function have been reported in patients with anemia, yet their pathophysiological role often remains unclear. PGC1β is a critical coactivator of mitochondrial biogenesis, with incr

Allman studieplan for utbildning pa forskarniva i koreografi 150603

Konstnärliga fakulteten i Malmö Dnr: U 2015/183 Allmän studieplan för utbildning på forskarnivå i koreografi ledande till konstnärlig doktorsexamen 1. Identifikation Utbildningens namn och inriktning: Utbildning på forskarnivå i koreografi Kod: KOKORE0 Omfattning i högskolepoäng: 240 Nivå: Forskarnivå Examensbenämning: Konstnärlig doktorsexamen i koreografi Engelsk examensbenämning: Doctor of Phil

https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/allman_studieplan_for_utbildning_pa_forskarniva_i_koreografi_150603.pdf - 2026-05-03

GEOR02 Course Analysis 2022

Gourse evaluation and analysis GEORO2 Geology Master's Degree Project, 45 hp October 2022 This course analysis was conducted in early October 2022, almost two years after the previous one. A link to the questionnaire has been sent by the library to every student who has completed the LUP (Lund University Publications) web publication procedure at the end of their respective course periods. Thirty

https://www.geology.lu.se/sites/geology.lu.se/files/2022-11/GEOR02%20Course%20analysis%202022.pdf - 2026-05-03

Protokoll Nämnden För GS 240603

Graduate School Nämnden för Graduate School, 2024-06-03 Närvarande Ledamöter Lena Karlsson Studierektor, Graduate School Leysan Storie Programansvarig, Mellanösternstudier Catia Gregoratti Programansvarig, Globala studier Marta Kolankiewicz Programansvarig, Genusstudier Christopher Swader Programansvarig, Samhällsvetenskaplig dataanalys Axel Fredholm Sociologen Ida Nafstad Rättssociologi Marta Kol

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2024-09/Protokoll%20Na%CC%88mnden%20fo%CC%88r%20GS%20240603.pdf - 2026-05-03

Ansokningsprocedur-pedagogisk-akakademi-2020-01-17

Postadress: Kansli S, Lunds universitet, Box 117, 221 00 LUND Besöksadress: Sandgatan 13, Lund växel: 046-222 00 00 E-post: kansli@sam.lu.se Webbadress: www.sam.lu.se Procedur för ansökan om bedömning av pedagogisk skicklighet Ansökan ställs till: Pedagogiska akademin Kansli S Samhällsvetenskapliga fakulteten Kontaktperson: Fakultetskoordinator Sökanden lämnar in: Pedagogisk portfölj (inkl. intyg

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/ansokningsprocedur-pedagogisk-akakademi-2020-01-17.pdf - 2026-05-03

Generella-kompetenser-samfak-2016

1 Generella kompetenser De kunskaper och färdigheter som genereras via teoretisk utbildning vid skolor och universitet kan klassificeras på olika sätt. En skiljelinje kan dras mellan å ena sidan rena ämneskunskaper och å den andra vad som ibland kallas för ”generella kompetenser”. Den första av dessa är nog den mest uppenbara. Att man förkovrar sig i sociologi, statsvetenskap, psykologi, geografi

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/generella-kompetenser-samfak-2016.pdf - 2026-05-03

Ttp 2015 ttpk10

Kursguide - Course Syllabus • • • Fastställande Kursplanen är fastställd av prodekanen med ansvar för grundutbildning vid de humanistiska och teologiska fakulteterna 2015-03-12 att gälla från och med 2015- 03-12, vårterminen 2015. Allmänna uppgifter Kursen ges som fristående kurs. Den kan normalt ingå i en generell examen på såväl grundnivå som avancerad nivå. Undervisningsspråk: svenska Kursens m

https://www.thm.lu.se/sites/thm.lu.se/files/ttp_2015_ttpk10.pdf - 2026-05-03

Laser Remote Microscopy for Insect Diversity Assessment

Recent insect decline prompts rapid online monitoring solutions with specificity for thousands of coexisting species.I demonstrate how microscopic and nanoscopic features of insects can aid differentiation of species and be retrieved with spectral lidar.

Dröjsmålstalan och EU-rätten – En undersökning av i vad mån förvaltningslagens dröjsmålstalan uppfyller unionsrättens krav på rättsskydd

Den 1 juli 2018 trädde den nya förvaltningslagen (2017:900) i kraft. I lagen ges enskilda, genom införandet av en dröjsmålstalan, för första gången i svensk förvaltningsrätt en generell rätt att föra talan mot förvaltningsmyndigheters passivitet. Om unionsrätten inte anger annat kommer den nya dröjsmålstalan, enligt principen om medlemsstaternas processuella autonomi, att tillämpas även vid förvalOn the first of July 2018, the new Swedish Administrative Procedure Act came into force. The Act introduces a new remedy against the inaction of administrative authorities (an action for failure to act, in Swedish “dröjsmålstalan”). Through the introduction of the new remedy, individuals are given a general right to appeal against the administrative authorities' inaction for the first time in

An Introduction to Dirichlet Series

En funktion som har fått mycket uppmärksamhet bland matematiker är den så kallade Riemanns zeta-funktion, som definieras med hjälp av en summa av oändligt antal termer, en så kallad serie: zeta(s) = 1 + 1/2^s + 1/3^s + 1/4^s + ... Här är s=a+ib en komplex variabel med en reell del a och en imaginär del, där i har egenskapen i^2=-1. Värdet på den här serien kommer givetvis bero på vilket värde pWe establish the central convergence properties of ordinary Dirichlet series, including the classical result by Bohr, providing uniform convergence of the series where it has a bounded analytic continuation. We also derive a lower bound for the supremum of Dirichlet polynomials using Kronecker's theorem, of which we see one proof. With this knowledge and some probability theory we can follow t