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Therapy Effects in Cerebral Folate Transport Deficiency with Hypomyelination Monitored by Multimodal Quantitative MR-Imaging

Myelin-sensitive quantitative (q) MRI techniques including MT (3D FLASH) and DTI (single-shot STEAM) are of growing importance to study white matter (WM) disorders in childhood. Cerebral folate transport deficiency is an inherited, treatable WM disorder with hypomyelination, developmental regression, movement disturbances, and epilepsy. One patient with this diagnosis and severe phenotype was trea

Small airway involvement in the late allergic response in asthma

Background: Allergy and asthma are closely linked. Inhalation of allergen induces an early allergic response (EAR) within the airways of allergic asthmatic subjects, which is followed by a late allergic response (LAR) in approximately 50% of the subjects. The LAR is defined as a drop in forced expiratory volume in 1 second (FEV1) from baseline usually occurring 4-8 hours after exposure and is beli

Acoustic trapping efficiency of nanoparticles and bacteria

In this paper we present a method to characterize the acoustic trapping efficiency of nanoparticles and bacteria when using seeding particles. Through the use of fluorescent microscopy and video analysis, single particles/bacteria were counted as they entered the acoustic trap at different flow focusing ratios and by comparing the amount of trapped objects to the amount of objects that were lost f

Brain damage and behavioural disorders in fish induced by plastic nanoparticles delivered through the food chain

The tremendous increases in production of plastic materials has led to an accumulation of plastic pollution worldwide. Many studies have addressed the physical effects of large-sized plastics on organisms, whereas few have focused on plastic nanoparticles, despite their distinct chemical, physical and mechanical properties. Hence our understanding of their effects on ecosystem function, behaviour

Expression of tSTAT3, pSTAT3 727 , and pSTAT3 705 in the epithelial cells of hormone-naïve prostate cancer

Background: The signal transducer and activator of transcription 3 (STAT3) pathway is observed to be constitutively activated in several malignancies including prostate cancer (PCa). In the present study, we investigated the expression of total STAT3 (tSTAT3) and two forms of activated phosphorylated STAT3 (pSTAT3 727 and pSTAT3 705 ) in tissue microarrays (TMA) of two cohorts of localized horm

Oxidative stress in birds along a NOx and urbanisation gradient : An interspecific approach

Urbanisation is regarded as one of the most threatening global issues for wildlife, however, measuring its impact is not always straight forward. Oxidative stress physiology has been suggested to be a useful biomarker of health and therefore, a potentially important indicator of the impact that urban environmental stressors, especially air pollution, can have on wildlife. For example, nitrogen oxi

Neighborhoods and mortality in Sweden : Is deprivation best assessed nationally or regionally?

BACKGROUND The association between neighborhood deprivation and mortality is well established, but knowledge about whether deprivation is best assessed regionally or nationally is scarce. OBJECTIVE The present study aims to examine whether there is a difference in results when using national and county-specific neighborhood deprivation indices and whether the level of urbanization modifies the ass

Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging

A hallmark of adult hematopoiesis is the continuous replacement of blood cells with limited lifespans. While active hematopoietic stem cell (HSC) contribution to multilineage hematopoiesis is the foundation of clinical HSC transplantation, recent reports have questioned the physiological contribution of HSCs to normal/steady-state adult hematopoiesis. Here, we use inducible lineage tracing from ge

Rationale for a Swedish cohort consortium

We herein outline the rationale for a Swedish cohort consortium, aiming to facilitate greater use of Swedish cohorts for world-class research. Coordination of all Swedish prospective population-based cohorts in a common infrastructure would enable more precise research findings and facilitate research on rare exposures and outcomes, leading to better utilization of study participants’ data, better

Commercial infant cereals contain high concentrations of endotoxins and viable Bacillus spp.

Background: Endotoxin may cause inflammation and increased intestinal permeability in infants with immature immune systems and gut microbiota. This study analysed the presence of endotoxin together with other potentially hazardous agents in commercial infant cereals. Methods: Four porridges and six milk cereal drinks bought in Sweden were analysed for the presence of endotoxins using Endosafe MCS.

End-of-life care among older cancer patients with intellectual disability in comparison with the general population : a national register study

BACKGROUND: Increasing life expectancy for people with an intellectual disability (ID) is resulting in more persons with cancer and a greater need for end-of-life (EoL) care. There is a need for knowledge of health care utilisation over the last year of life to plan for resources that support a high quality of care for cancer patients with ID. Therefore, the aims of the study were to compare (1) h

Computerization of the Control Function in a Process Industry: A Case Study

Computerization of control room functions changes the work for the operators to a great extent. Their mental picture of the process, their possibilities to control the process for productivity and quality, the work content, the physical and the social working environment are examples of conditions which are changed one way or another. In order to be able to control the computerization process in a

Harvesting the Coral Gardens: An Ethnobiological Study of Marine Gathering in the Tongan Islands, Polynesia

Seaweeds and marine invertebrates of the lagoons and reefs have, ever since the initial settlement almost 3.500 years ago, been a very important source of food and raw materials for the people of the Tongan islands. This study is an attempt to combine anthropological and biological perspectives in documenting and discussing, in contemporary as well as ancient contexts, the gathering/collecting of

Peptide folding and local unfolding of SOD1 in the presence of interacting macromolecular crowders - a Monte Carlo approach

Proteiner är några av livets beståndsdelar. Komplexa molekyler som förser våra kropparmed både struktur och funktion, bland annat i muskler. De är kedjor av aminosyror,som vartefter de skapas i kroppen ofta veckar sig till en specifik tredimensionell strukturför att kunna utföra den funktion de har optimerats för under evolutionens gång.Uppstår fel i denna process kan felaktiga strukturer, som oftA protein chain often folds into a functional, specific three dimensional structure. Failurein this process can in some cases lead to disease, e.g. the misfolding disease ALS. Themechanisms behind the folding has mostly been studied under dilute conditions. However,in the natural cellular environment of proteins, the concentration of macromolecules is highand it is believed that this affects vario

Interpretation of conventional survival analysis and competing risk analysis : An example of hypertension and prostate cancer

Most clinical studies use conventional methods for survival analysis and calculate the risk of the event of interest, however, it is important to understand that the study population is also at risk of competing events, for example death from other causes. Moreover, the risk of competing events may be dependent on the participants' characteristics. Whether competing risks are taken into account or

Hendrickson cary thesis 2009

To Develop or Conserve? A Case Study on Biodiversity Protection and Local Sustainable Development in Jiuzhaigou, China A thesis submitted in fulfillment of the requirements for the degree of Master of Science LUMES International Master‘s Programme in Environmental Studies and Sustainability Science Lund University Center for Sustainability Studies Lund University Lund, Sweden August 2009 Author: S

https://www.lumes.lu.se/sites/lumes.lu.se/files/hendrickson_cary_thesis_2009.pdf - 2026-04-27

Lai yokechin

Master Thesis LUMES 1999-2000 Lond University Correlation of The Planning Process with Environmental Responsive and Healthy Buildings Case studies in Sweden and Malaysia. Author: YokeChin Lai, M. Eng. (Mechanical), Institute ofNoise & Vibration, Universiti Teknologi Malaysia, Kuala Lumpur, Malaysia. e-mail: yokechin lai@hotmai1.com Supervisor: Kerstin Gustafsson, Environmental Manager, Division of

https://www.lumes.lu.se/sites/lumes.lu.se/files/lai_yokechin.pdf - 2026-04-27

Link-manual 2015-03-04

LINK-manual 2015-03-04         LINK   Användarmanual           Lunds  universitet   Externa  relationer               Utkast   4  mars  2015     2       Innehåll     Introduktion  –  vad  är  LINK?  ..........................................................................................................................  6   Alumnrelationer  ........................................................

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/link-manual_2015-03-04.pdf - 2026-04-27