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Corticosteroid-binding globulin: A possible early predictor of infection in acute necrotizing pancreatitis

Objective. Infected pancreatic necrosis is the main cause of death in patients with acute pancreatitis, and therefore its early prediction is of utmost importance. Endogenous cortisol metabolism plays a basic role both in the course of acute pancreatitis and in the process of infection. The purpose of this study was to analyze corticosteroid-binding globulin (CBG), total cortisol, calculated free

Care managers' view of family influence on needs assessment of older people

Research has shown that families experience poor involvement in needs assessment of older people while little is known about municipal care managers' views of family participation. The aim was to explore how municipal care managers view families' participation in and influence on needs assessment of older people receiving public home help. Individual interviews (n = 26) were conducted with care ma

Impact of yoga on blood pressure and quality of life in patients with hypertension - a controlled trial in primary care, matched for systolic blood pressure

Background: Medical treatment of hypertension is not always sufficient to achieve blood pressure control. Despite this, previous studies on supplementary therapies, such as yoga, are relatively few. We investigated the effects of two yoga interventions on blood pressure and quality of life in patients in primary health care diagnosed with hypertension. Methods: Adult patients (age 20-80 years) wit

Integrating climate change adaptation, disaster risk reduction and urban planning: A review of Nicaraguan policies and regulations

The integration of risk reduction and climate change adaptation has become an urgent task in addressing increasing urban risk more effectively and efficiently. This paper analyses the extent to which climate change adaptation is integrated into the policies and regulatory frameworks that guide urban risk reduction in Nicaragua, and discusses related progress. The results reveal significant progres

Increasing cognitive interference modulates the amplitude of the auditory brainstem response

Background: Despite the presence of efferent neural pathways from the cortex to brainstem, evidence for cognitive inhibition and sensory gating on the auditory brainstem has been mixed. Some previous studies have suggested auditory brainstem responses (ABR) can be affected by cognitive load whereas others have not. Purpose: The present study explores if the ABR recorded from adults with normal hea

Unpacking the role of universities in the emergence, development and impact of social innovations : A systematic review of literature

The systematic review of universities and social innovations was carried out by placing universities within the broad framework of social innovation. Focus on social innovation as a response to development and societal problems, the review adopted a three-prong approach by analysing the drivers, process and impact of social innovations in the three core missions of universities: teaching, research

Fragmentation in disaster risk management systems: A barrier for integrated planning

The need to integrate climate change adaptation (CCA) considerations into disaster risk management (DRM) systems is widely recognised. However, successful integration, and thus the implementation of integrated planning measures, is difficult in practice. To understand and reduce the problems encountered, it is important to investigate systemic challenges. These challenges are rooted in the interac

Adaptive predictive control for software systems

Self-adaptive software systems are designed to support a number of alternative solutions for fulfilling their requirements. These define an adaptation space. During operation, a self-adaptive system monitors its performance and when it finds that its requirements are not fulfilled, searches its adaptation space to select a best adaptation. Two major problems need to be addressed during the selecti

Assessment of somatosensory profiles by quantitative sensory testing in children and adolescents with and without cerebral palsy and chronic pain

Objective: We investigated differences in somatosensory profiles (SSPs) assessed by quantitative sensory testing in children and adolescents with cerebral palsy (CCP) with and without chronic pain and compared these differences to those in a group of typically developed children and adolescents (TDC) with and without chronic pain. Method: All included subjects were consecutively recruited from and

Effect of crop maturity stages and lactic acid fermentation on nutrient absorption properties, and bioaccessibility of Fe, Zn and Ca in Spinacia oleracea L

This study explores the variability in nutritional composition of spinach at different maturity stages and assesses the effects of fermentation on reducing oxalates and enhancing minerals bioaccessibility. Spinach harvested at the age of 4th to 6th weeks was processed as raw, blanched, and fermented to develop freeze-dried powders. The growth stages of spinach from the 4th to the 6th week showed a

Role of the polyamine transporter PotABCD during biofilm formation by Streptococcus pneumoniae

Streptococcus pneumoniae is a bacterium of great global importance, responsible for more than one million deaths per year. This bacterium is commonly acquired in the first years of life and colonizes the upper respiratory tract asymptomatically by forming biofilms that persist for extended times in the nasopharynx. However, under conditions that alter the bacterial environment, such as viral infec

Quality of life for patients with advanced gastrointestinal cancer randomised to early specialised home-based palliative care: the ALLAN trial

BackgroundThe primary aim of specialised palliative care (SPC) is to improve the quality of life (QoL) for patients with a high symptom burden from a life-threatening disease. This randomised study aimed to assess the QoL impact of early integration of SPC alongside tumour-specific palliative treatment in patients with gastrointestinal (GI) cancers.MethodsWe randomly assigned ambulatory patients w

Brief Introduction to Particle Accelerators

This lecture is a brief introduction to charged particle accelerators. The aim is to provide the reader with basic concepts and tools needed to describe the motion of charged particles under the action of guiding and focussing fields, with an emphasis on those aspects that are relevant to understanding and quantifying how accelerator vacuum systems affect accelerator performance. Even though the f