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Software developing organizations strive to achieve flexibility to maintain a competitive advantage. There is no common understanding of what characterize flexibility for a software organization beyond the scope of the software product. Without a common understanding, it is difficult to evaluate the degrees of flexibility of software development approaches. The aim of this literature review is to

We investigated multivoxel proton magnetic resonance spectroscopy (1H-MRS) biometrics for preoperative differentiation and prognosis of patients with brain metastases (MET), low-grade glioma (LGG) and high-grade glioma (HGG). In total, 33 patients (HGG, 14; LGG, 9; and 10 MET) were included. 1H-MRS imaging (MRSI) data were assessed and neurochemical profiles for metabolites N-acetyl aspartate (NAA

Purpose: The purpose of this paper is to develop, implement, test and further enhance a framework for measuring organizational change initiatives. Design/methodology/approach: The conceptual part of the framework is based on the structured analysis of existing literature. The framework was further developed during an action research (AR) study where the authors developed, implemented, evaluated an

BackgroundRight ventricular (RV) function is a major determinant of outcome in patients with pulmonary hypertension. Cardiac magnetic resonance (CMR) is gold standard to assess RV ejection fraction (RVEFCMR), however this is a crude measure. New CMR measures of RV function beyond RVEFCMR have emerged, such as RV lateral atrio-ventricular plane displacement (AVPDlat), maximum emptying velocity (S’C

BACKGROUND: Iodine has been suggested to protect against breast cancer, but there are no epidemiologic studies on individual risk. An interesting finding is that in areas where the exposure to both selenium and iodine are high (e.g., Japan), the risk of breast cancer is lower than in areas where selenium is high and iodine low (e.g., United States), or in areas where both are low (e.g., Northern E

Ras homolog gene family member C (RhoC) is a GTPase involved in cell migration, implicated in epithelial-mesenchymal transition and treatment resistance and metastasis of cancer. For example, RhoC has been shown to be involved in resistance to radiation in cervical carcinoma. Here, the effect of X-ray irradiation on RhoC expression in prostate cancer (PCa) xenografts was investigated in both xenog

The main purpose of this study is to investigate how members of staff at group homes (LSS-bostäder) reason about the service users’ rights to self-determination in everyday life. Additionally, this study aims to investigate how group homes as a place may affect the fulfillment of self-determination rights. The following theories “The theory of Recognition” and ”the Principle of normalization”, the

Recessive diseases arise when both copies of a gene are impacted by a damaging genetic variant. When a patient carries two potentially causal variants in a gene, accurate diagnosis requires determining that these variants occur on different copies of the chromosome (that is, are in trans) rather than on the same copy (that is, in cis). However, current approaches for determining phase, beyond pare

BACKGROUND: Accumulating evidence suggests a relationship between endometrial cancer and ovarian cancer. Independent genome-wide association studies (GWAS) for endometrial cancer and ovarian cancer have identified 16 and 27 risk regions, respectively, four of which overlap between the two cancers. We aimed to identify joint endometrial and ovarian cancer risk loci by performing a meta-analysis of

Plasma metabolomics holds potential for precision medicine, but limited information is available to compare the performance of such methods across multiple cohorts. We compared plasma metabolite profiles after an overnight fast in 11,309 participants of five population-based Swedish cohorts (50–80 years, 52% women). Metabolite profiles were uniformly generated at a core laboratory (Metabolon Inc.)

Disorder is an intrinsic feature of all solids, from crystals of atoms to superlattices of colloidal nanoparticles. Unlike atomic crystals, in nanocrystal superlattices, a single misplaced particle can affect the positions of neighbors over long distances, leading to cumulative disorder. This elusive form of collective particle displacement leaves clear signatures in diffraction, but little i

Atomic layer deposition (ALD) of HfOx layers has emerged as a promising strategy for interface passivation in chalcopyrite-based thin-film solar cells. However, the nucleation dynamics of (Ag,Cu)(In,Ga)Se2 (ACIGS) absorbers remain insufficiently understood, particularly regarding the interplay between absorber composition and alkali postdeposition treatments (PDTs). Here, we employ in situ ambient

This paper explores how entrepreneurial legacies can have broader social impact beyond the identity of founders, the organization that they created, or their own philanthropic activity. Thus, we illustrate how, in the South African context, social entrepreneuring may be understood as the values-driven, relational brokering of societal legacies amongst a variety of entrepreneurs. At the heart of th

Behavioral, physiological, and life-history adaptations to the lunar cycle are global phenomena across trophic levels and ecosystems yet remain poorly understood because of the challenges of studying free-living organisms at night. We show that the lunar cycle regulates both daily foraging activity and foraging success in the red-necked nightjar-a nocturnal avian insectivore-and that moonless peri

Rapporten visar att det finns en gedigen vetenskaplig evidensbas för att utforma åtgärder inom den gemensamma jordbrukspolitiken som bidrar till restaurering av jordbrukslandskap i linje med EU:s naturrestaureringsförordning. Evidensbasen kan stärkas genom en systematisk sammanställning av resultat från restaureringsprojekt, och författarna föreslår adaptiv restaurering för att hantera kontextbero

Popular Abstract in Swedish Svensk Kärnbränslehantering AB, SKB, har i uppdrag att ta hand om allt radioaktivt avfall från de svenska kärnkraftverken. En av förutsättningarna för att SKB ska få tillstånd att uppföra inkapslings- och slutförvars¬anläggningarna är att metod och teknik för att försluta kapslarna finns. De förslutna kapslarna ska uppfylla de krav på långsiktig säkerhet som SKB, myndigThis thesis presents the development to reliably seal 50 mm thick copper canisters containing the Swedish nuclear waste using friction stir welding. To avoid defects and welding tool fractures, it is important to control the tool temperature within a process window of approximately 790 to 910°C. The welding procedure requires variable power input throughout the 45 minute long weld cycle to keep th