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Bundy Academy Pristagare

Pristagare 2025  Andreas Edsfeldt ”Stora priset” om 3.000.000 SEK till framstående etablerade forskare som tidigare erhållit Bundy Academy’s ”Lilla pris” tilldelas Andreas Edsfeldt med motivering "framstående forskare med projekt av vetenskaplig världsklass" till projektet: Targeting mechanisms of an impaired fibrotic tissue repair to prevent diabetes associated vascular complications. Ashkan Laba

https://www.medicin.lu.se/samverkan/stiftelser/bundy-academy/bundy-academy-pristagare - 2026-07-03

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Monoclonal gammopathy of undetermined significance (MGUS) was identified in 3.2% of 21 463 residents of Olmsted County, Minnesota, 50 years of age or older. The risk of progression to multiple myeloma, Waldenstrom's macroglobulinemia, AL amyloidosis or a lymphoproliferative disorder is approximately 1% per year. Low-risk MGUS is characterized by having an M protein < 15 g/l, IgG type and a normal

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Popular Abstract in Swedish De ökande kraven på högre datahastigheter inom trådlös kommunikation ställer allt högre krav på både radiosändare och mottagare, då dessa behöver utnyttja fler frekvensband med större bandbredd vid högre frekvenser. Fokus i denna avhandling ligger på högfrekvensdelen av radiomottagaren, som består av lågbrusförstärkare, blandare, och oscillatorer vid mikrovågsfrekvenserThe increasing demand for high data rates in wireless communication systems is increasing the requirements on the transceiver front-ends, as they are pushed to utilize more and wider bands at higher frequencies. The work in this thesis is focused on receiver front-ends composed of Low Noise Amplifiers (LNAs), Mixers, and Voltage Controlled Oscillators (VCOs) operating at microwave frequencies. Tra

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To examine whether increasing fasting plasma glucose (FPG) levels were associated with worsening left ventricular (LV) diastolic function, independently of LV mass index (LVMI) in elderly, otherwise healthy subjects.

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Carbohydrate-deficient transferrin (CDT) is a generic term that refers to the transferrin glycoforms whose concentration in blood is temporarily increased by sustained alcohol consumption. Due to high clinical specificity, CDT was proposed as a biomarker of heavy alcohol use and has been available for about 20 years. A number of methods have been developed for CDT measurement based on different an

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Protein phosphorylation is one of the most important and common ways of regulating protein function in cells. However, phosphopeptides are difficult to analyse, ionising poorly under standard MALDI conditions. Several methods have been developed to deal with the low sensitivity and specificity of phosphopeptide analysis. Here, we show an approach using a simple one-step beta-elimination/Michael ad

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In the spectrum of an emission-line region ejected from the massive star Eta Carinae, called the strontium filament (SrF), forbidden lines from many elements, in particular [Sr II] and [Ti II], are observed. These lines are strong in this specific region and valuable for plasma diagnostics. Forbidden lines are not easily produced in laboratory light sources and the atomic parameters for these line

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Background Postoperative policies of "wait-and-see" and radiotherapy for low-grade glioma are poorly defined. A trial in the mid 1980s established the radiation dose. In 1986 the EORTC Radiotherapy and Brain Tumor Groups initiated a prospective trial to compare early radiotherapy with delayed radiotherapy. An interim analysis has been reported. We now present the long-term results. Methods After s

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Adeno-associated virus (AAV) capsid modification enables the generation of recombinant vectors with tailored properties and tropism. Most approaches to date depend on random screening, enrichment, and serendipity. The approach explored here, called BRAVE (barcoded rational AAV vector evolution), enables efficient selection of engineered capsid structures on a large scale using only a single screen

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Oxidation of SO2.nH2O/HSO3-/SO32- by Pt(CN)4Cl22- has been studied at 25-degrees-C and 1.0 M ionic strength in acidic aqueous solution by use of stopped-flow spectrophotometry. The stoichiometry of the reaction is 1:1 according to Pt(CN)4Cl22- + HSO3 + H2O --> Pt(CN)42- + 2Cl- + HSO4- + 2H+. It is first-order with respect to both [Pt(IV)] and [S(IV)]. The pH-dependence in the region 0.3 < pH < 4.5

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Cellobiose dehydrogenase (CDH) is a fungal extracellular flavocytochrome capable of direct electron transfer (DET). Unlike other CDHs, the pH optimum for CDHs from Corynascus thermophilus (CtCDH) and Humicola insolens (HiCDH) is close to the human physiological pH in blood (7.4). These are, therefore, interesting candidates for glucose measurements in human blood and the application in enzymatic f

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Background: The fixation of uncemented tibia components in total knee arthroplasty may rely on the bone quality of the tibia; however, no previous studies have shown convincing objective proof of this. Component migration is relevant as it has been shown to predict aseptic loosening. Methods: We performed 2-year follow-up of 92 patients who underwent total knee arthroplasty surgery with an uncemen

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Kontrollerade experiment (t.ex. A/B test) används av många företag med användarintensiva produkter för att förbättra mjukvara med hjälp av användardata. Några företag anammar ett experimentdrivet tillvägagångssätt för mjukvaruutveckling med kontinuerliga experiment (KE). Med KE så utvärderas alla förändringar som påverkar användare med ett experiment och det finns specialiserade roller som aktivt Controlled experiments (i.e. A/B tests) are used by many companies with user-intensive products to improve their software with user data. Some companies adopt an experiment-driven approach to software development with continuous experimentation (CE). With CE, every user-affecting software change is evaluated in an experiment and specialized roles seek out opportunities to experiment with functiona

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This paper discusses the key legal issues arising from the constitutional conceptions of both the EU and the UK in the latter’s withdrawal process. It argues that the adherent Brexit dilemma is mainly the result of the UK’s non-codified constitution on the one hand, exposing legal uncertainty over institutional procedures, regional involvement, or the precise status of international law. Neverthel

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Objective: Fenestrated endovascular aneurysm repair (FEVAR) is a well established treatment for complex abdominal aortic aneurysms (AAAs). FEVAR with custom made devices (CMDs) has limitations in both the emergency and elective settings due to time consuming manufacture. “Off the shelf” (OTS) fenestrated stent grafts are a potential solution. The primary goal was to evaluate the five year outcome