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Single-strand RNA-binding proteins (RBPs) are involved in many aspects of RNA metabolism and in the regulation of gene transcription. The RBP RBM3 was recently suggested to be a proto-oncogene in colorectal cancer; however, such a role has not been corroborated by previous studies in the colon or other tumor types, and the prognostic implications of tumor-specific RBM3 expression remain unclear. M

In embedded systems, the computing resources are often scarce and several control tasks may have to share the same computer. In this brief, we assume that a set of feedback controllers should be implemented on a single-CPU platform. We study the problem of optimal sampling period assignment, where the goal is to assign sampling rates to the controllers so that the overall control performance is ma

Recent papers have proposed to design scheduling algorithms entirely as discrete-time controllers, i.e., to refrain from preserving the already installed scheduler, and replace it completely. At the cost of some system re-design impact, this new approach has been proved to yield significant advantages in terms of code size and simplicity, and above all to open the way to a system-theoretical analy

Mobile robots and robotic manipulators have traditionally been used separately performing different types of tasks. For example, industrial robots have typically been programmed to follow trajectories using position sensors. If combining the two types of robots and adding sensors new possibilities emerge. This enables new applications, but it also raises the question of how to combine the sensors

The damping ratio is a key performance measure in systems that can be modelled as networks of masses and springs. We derive a lower bound on this quantity that applies to such networks when the masses are subject to viscous damping. The result allows the size of the damping ratio to be understood as a function of the system parameters. We use this to derive a decentralised criterion which, if sati

In this paper, we address mixed-criticality applications characterized by their safety criticality and time-dependent performance, which are virtualized on a Fog Computing Platform (FCP). The FCP is implemented as a set of interconnected multicore computing nodes, and brings computation and communication closer to the edge of the network, where the machines are located in industrial applications.

This paper investigates potential factors that control the El Niño–Southern Oscillation (ENSO) Spring Persistence Barrier (SPB) strength in two different ENSO regimes and apply it to explain the ENSO SPB strength modulation after the 21st century. In a damped, noise-driven model, the theoretical solution of SPB strength illustrates that a weaker ENSO growth rate strengthens SPB. In the self-sustai

We examine the favorable propagation (FP) behavior of a massive multi-user multiple-input-multiple-output (MU-MIMO) system equipped with a uniform linear array (ULA), horizontal uniform rectangular array (HURA) or uniform circular array (UCA) using a ray-based channel model with user cluster sharing. We demonstrate FP for these systems and provide analytical expressions for the mean-squared distan

Class-C operation is leveraged to implement a K-band CMOS voltage-controlled oscillator (VCO) where the upconversion of 1/f current noise from the cross-coupled transistors in the oscillator core is robustly contained at a very low level. Implemented in a bulk 28-nm CMOS technology, the 12%-tuning-range VCO shows a phase noise as low as -112 dBc/Hz at 1-MHz offset (-86 dBc/Hz at 100 kHz offset) fr

Efficient mitigation of power amplifier (PA) nonlinear distortion in multi-user hybrid precoding based broadband mmWave systems is an open research problem. In this article, we carry out detailed signal and distortion modeling in broadband multi-user hybrid MIMO systems, with a bank of nonlinear PAs in each subarray, while also take the inevitable crosstalk between the antenna/PA branches into acc

Smart vehicles are emerging as a possible solution for multiple concerns in road traffic, such as mobility and safety. This work presents radio localization methods based on simultaneous direction of arrival (DOA), time-delay, and range estimation using the SAGE algorithm. The proposed methods do not rely on external sources of information, such as global navigation satellite systems (GNSS). The p

Assessments of long-term changes of air quality and global radiative forcing at a large scale heavily rely on satellite aerosol optical depth (AOD) datasets, particularly their temporal binning products. Although some attempts focusing on the validation of long-term satellite AOD have been conducted, there is still a lack of comprehensive quantification and understanding of the representativeness

Iterative learning control (ILC) is an approach to improve the performance of a system that repeats the sameoperation. In this paper, we apply the theory of pseudospectra to transient analysis of ILC. The focus of thispaper is on frequency-domain analysis of filter-based ILC. Moreover, the effect of finite trial length on thetransient growth is discussed.

We show that the structured singular value of a real matrix with respect to five full complex uncertainty blocks equals its convex upper bound. This is done by formulating the equality conditions as a feasibility SDP and invoking a result on the existence of a low-rank solution. A counterexample is given for the case of six uncertainty blocks. Known results are also revisited using the proposed ap

Wireless connectivity is becoming an important feature in cars, which together with recent developments in car design point to the need to accurately predict the performance of real antennas in simulation, to speed up the design cycle. However, it is challenging to accurately represent structurally complex real cars in simulation. This paper proposes a car model simplification approach for designi

As an emerging technology and evolution that goes beyond massive multi-input multi-output (MIMO), large intelligent surface (LIS) has gained much interest. LIS acts as an electromagnetic surface that can transmit, redirect, and receive radiating signals across its entire contiguous surface. It allows for unprecedented energy-focusing, data-transmission and terminal-positioning, and can fulfill the

We characterize a class of systems for which the H-infinity optimal control problem can be simplified in a way that enables sparse solutions and efficient computation. For a subclass of the systems, an optimal controller can be explicitly expressed in terms of the matrices of the system's state-space representation. In many applications, the controller given by this formula, which is st

A novel method using the cloud to implement a variable horizon model predictive controller is presented. In case of sudden long delays and downtime, a graceful degradation is used. Robust, best effort strategies allow industrial grade use of the powerful, efficient, and quickly improving cloud ecosystems. The variable horizon strategy finds use in, for example, non-linear control problems, and the

A two-tier architecture for cloud-based MPC is presented consisting of a high rate MPC in the cloud and a low rate MPC on the local device. The system use the cloud MPC as the nominal controller but switches to local MPC in case of connectivity loss. The two MPCs are designed to be as similar to each other as possible except for the sampling rate. Different alternatives for when to execute the loc