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In comparison to other human cancer types, malignant melanoma exhibits the greatest amount of heterogeneity. After DNA-based detection of the BRAF V600E mutation in melanoma patients, targeted inhibitor treatment is the current recommendation. This approach, however, does not take the abundance of the therapeutic target, i.e., the B-raf V600E protein, into consideration. As shown by immunohistoche

Economies in transition (EiTs) (e. g. Ukraine (UA), Belarus, Lithuania (LU), Moldova, etc.) face broad needs for energy security enhancement, energy diversification, revitalisation of agriculture and improvements in the state of the environment. Development of national bioenergy potentials can contribute to delivering solutions to these problems. However, EiTs face technical, political, financial,

In the last two decades, health promotion strategies have gained significant attention in end-of-life care contexts—engendering greater focus on community and informal care in policy and healthcare spheres in liberal welfare-states. The emergence of health-promoting palliative care (HPPC) in the Nordic context presents a unique challenge to the abiding social contract of care which emphasizes the

Aerosol particles are a complex component of the atmospheric system which influence climate directly by interacting with solar radiation, and indirectly by contributing to cloud formation. The variety of their sources, as well as the multiple transformations they may undergo during their transport (including wet and dry deposition), result in significant spatial and temporal variability of their p

The combination of features from the public and private sectors in jointly owned companies imposes challenges to the governance and control mechanisms of these organisations, which have been criticised for lacking accountability. Where there is fragmented ownership, the interests of different owners need to be coordinated. The aim of this article is to consider how such companies can be governed i

Context: Uncertainty is an unavoidable issue in software engineering and an important area of investigation. This paper studies the impact of uncertainty on total duration (i.e., make-span) for implementing all features in operational release planning. Objective: The uncertainty factors under investigation are: (1) the number of new features arriving during release construction, (2) the estimated

Medical decision-making is critical and the decisions are made under uncertain, complex, and dynamic conditions. In this regard, practitioners’ experiences and perceptions may provide a bottom-up knowledge of the issues, as well as a corresponding support system that assists them in learning to make decisions in critical situations. The current study aimed to examine these experiences in the Pakis

En ökande användning av ammonium genom samhälls- och industriell utveckling hotar utvatten runt om i världen. För att skydda det akvatiska ekosystemet och dricksvattenresurserna kan ammonium avlägsnas med biologisk behandling vid avloppsreningsverk. Utvecklingen av avloppsreningsverk under det senaste århundradet syftar till att implementera lösningar som är kostnads- och energieffektiva, har en lAn increasing usage of ammonium through societal and industrial development is threatening the water bodies around the world. To protect the aquatic ecosystem and drinking water resources, ammonium can be removed with biological treatment at wastewater treatment plants (WWTP). The development of WWTPs in the last century is aiming to implement solutions, which are cost and energy efficient, have a

Growth and Risk for Islet Autoimmunity and Progression to Type 1 Diabetes in Early Childhood: The Environmental Determinants of Diabetes in the Young Study Helena Elding Larsson,1 Kendra Vehik,2 Michael J. Haller,3 Xiang Liu,2 Beena Akolkar,4 William Hagopian,5 Jeffrey Krischer,2 Åke Lernmark,1 Jin-Xiong She,6 Olli Simell,7 Jorma Toppari,7,8 Anette-G. Ziegler,9 and Marian Rewers,10 for the TEDDY S

https://www.teddy.lu.se/sites/teddy.lu.se/files/07182017_679_54_mp24_larsson_diabetes_2016.pdf - 2026-06-12

Pion photo production from the nucleon is an important process utilized to understand the structure of the nucleon and the fundamental dynamics of the nucleon system. The neutral pion production has been extensively studied resulting in valuable data sets. However, much less data is available for charged pion photo production at energies below 200 MeV. In order to get a reliable data set for π+, f

In recent years, researchers worldwide have become increasingly interested in the phenomenon of code-switching in the multilingual classroom. The paper aims to try to understand when and why teachers in Swedish for Immigrants (SFI) schools code-switch in their classrooms. It analyses the methods and reasons for teachers’ code-switching in the SFI classroom. A case study was conducted by means of a

This work presents the development and evaluation of a Direct Membrane Filtration (DMF) concept for municipal wastewater treatment, integrating microsieving, microfiltration/ultrafiltration (MF/UF), and downstream polishing with activated carbon. DMF enables the efficient separation of particulate organic matter directly from raw wastewater, producing a retentate suitable for enhanced biogas produ

Surface physics play an outsized role in nanostructured electronic devices such as solar cells. Semiconductor nanowires are perfect candidates for advanced solar cells due to their outstanding light absorption properties and their flexibility in axially stacking materials of different doping and band gap. Due to nanowire geometry, however, their surfaces dominate device performance and at the same