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Despite progress over the last decades, East Africa has one of the highest ratios of preventable maternal mortality in the world. This qualitative case study sheds light on Midwife-Led Care (MLC) in Ethiopia, Kenya, Malawi and Somalia. MLC is a model of care associated with improved health outcomes and enhanced utilization of health systems resources. Nevertheless, the model is not properly integr
Objectives: Within the European Prospective Investigation into Cancer and Nutrition (EPIC) study, the performance of 24-h dietary recall (24-HDR) measurements as reference measurements in a linear regression calibration model is evaluated critically at the individual (within-centre) and aggregate (between-centre) levels by using unbiased estimates of urinary measurements of nitrogen and potassium
Store-operated Ca2+ influx represents a major route by which cytosolic Ca2+ can be elevated during platelet activation, yet its molecular identity in this cell type remains highly controversial. Using quantitative RT-PCR analysis of candidate receptor-operated cation entry pathways in human platelets, we show a 30-fold higher expression of message for the recently discovered Orai1 store-operated C
The Bicoid (Bcd) protein gradient in Drosophila serves as a paradigm for gradient formation in textbooks. To explain the generation of the gradient, the ARTS model, which is based on the observation of a bcd mRNA gradient, proposes that the bcd mRNA, localized at the anterior pole at fertilization, migrates along microtubules (MTs) at the cortex to the posterior to form a bcd mRNA gradient which i
Mitigation of greenhouse gas (GHG) emissions is essential for us humans to curb climate change. Around a fifth of the anthropogenic GHG emissions stem from the construction sector. Much come from energy used for space and water heating within buildings, but an increasing proportion comes from the manufacturing of the building materials and is virtually embodied within buildings. This is called Emb
Over the past 150 years, industrialization, globalization and population growth have altered the planet and its natural conditions at a rapid pace. In this new era, the Anthropocene, environmental degradation has come to a state where sustainable ecosystem management has developed into an urgent quest for humans to maintain their own life-support system. The ecosystem services (ES) concept, initia
The EU procured for roughly 202000 MEUR (14% of the EU GDP) during 2021 in the public sector. The majority of these contracts are traditional, linear business model purchases. The EU has been developing several strategies, guidelines, and policies for sustainable purchasing, with Circular Public Procurement for a Circular Economy (CE) being one of them, but the implementation rate is low. Electron
Under de senaste åren har transrättighetsrörelsen fått ökad spridning och uppmärksamhet både inom den queera rörelsen och i västvärlden och i media överlag. Debatter om att implementera ett tredje juridiskt kön för de personer som inte vill vara registrerade som man eller kvinna, och för personer födda med tvetydiga primära eller sekundära könsorgan, har ökat och nya policys implementeras i oIn recent years, the trans rights movement has gained a lot of traction and publicity both inside the queer movement and in western society and media at large. Debates on implementing a third legal gender for people who wish to not be registered as male or female, and for people born with ambiguous sex characteristics, have increased and new policies are being implemented in different countrie
Online sports betting is a billion-dollar industry with fierce competition to deliver the best possible experience. To be able to withstand the competition from rivals, bookmakers needs to be able to differentiate themselves with innovative and cutting edge solutions that offers a complete user experience. The goal of this master thesis is to investigate how sportsbook users perceive current betti
Examining the relation between Swedish households’ debt, property price and interest rates are important when forming monetary policy implications. Several studies have examined the driving factors of household debt and property price, however the results are inconclusive. This thesis differs from previous research as it includes the variable interest to income ratio, instead of debt ratio, as the
The COVID-19 pandemic has drawn attention to food insecurity in developed countries. Despite adequate levels of agricultural production, consumers experienced demand-induced scarcity. Understanding the effects on nutrition and the environment is limited, yet critical to informing ecologically embedded mitigation strategies. To identify mitigation strategies, we investigated wheat flour and egg ret
While Bayesian Optimization (BO) is a very popular method for optimizing expensive black-box functions, it fails to leverage the experience of domain experts. This causes BO to waste function evaluations on bad design choices (e.g., machine learning hyperparameters) that the expert already knows to work poorly. To address this issue, we introduce Bayesian Optimization with a Prior for the Optimum
Objectives Peak exercise systolic blood pressure (SBP) is associated with future cardiovascular disease (CVD) and mortality. We aimed to evaluate the predictive value of different SBP patterns at the end of exercise with these outcomes. Methods We studied 6329 adults (45% women) referred for exercise testing, with test duration of 6-14 min, maximal effort and valid SBP measurements at the end of e
Labile organic carbon is a major nutrient, controlling microbial activity in aquatic ecosystems and contributing to the global cycling of carbon. During the production and distribution of drinking water, labile carbon fractions often escape treatment, which threatens water quality and biostability. This study proposes and compares two rapid methods for monitoring the production and removal of labi
Building performance predictions and their reliability rely heavily on weather data inputs. Climate is affected by spatial and temporal differences related to climate change and urban heat island effects, but the weather files used in building performance simulations (BPS) often remain unchanged and may represent weather observations generated from inadequate space and time for their application.
Biochemical analyses of blood can decipher physiological conditions of living animals and unravel mechanistic underpinnings of life-history strategies and trade-offs. Yet, researchers in ecology and evolution often face constraints in which methods to apply, not least due to blood volume restrictions or field settings. Here, we test the suitability of a portable biochemical analyser (Zoetis VetSca
AIMS: Vascular atherosclerotic calcification is a pathological process marked by the abnormal deposition of calcium minerals in the intima. Asporin (ASPN) is a small leucine-rich proteoglycan which interacts with collagen and calcium. Due to its role in matrix mineralization, we hypothesized that ASPN might act as a regulator of vascular calcification, thereby promoting atherosclerotic plaque stab
Hard-to-heal wounds are a growing human and financial concern, constituting approximately 1–3% of the healthcare budget. Wound care is not a medical specialty and is often not prioritized within healthcare. A large portion of the cost and suffering caused by wounds has the potential to be mediated through improved knowledge and effectivised workflows. One potential way to achieve this is through t
