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Ischaemic heart disease is the leading cause of death worldwide. The common denominator for plaques causing acute coronary syndrome (ACS) is lipid accumulation, either as a lipid core or lipid pools. An intracoronary imaging device to detect lipid-rich plaques (LRPs) could therefore identify most of the plaques causing ACS and sudden death. Near-infrared spectroscopy combined with intravascular ul
Measurements of normalized differential cross sections for top-quark pair production are presented as a function of the top-quark transverse momentum, and of the mass, transverse momentum, and rapidity of the t (t) over bar system, in proton proton collisions at a center-of-mass energy of root s = 7 TeV. The data set corresponds to an integrated luminosity of 4.6 fb(-1), recorded in 2011 with the
Winter acclimatization in birds is a complex of several strategies based on metabolic adjustment accompanied by long-term management of resources such as fattening. However, wintering birds often maintain fat reserves below their physiological capacity, suggesting a cost involved with excessive levels of reserves. We studied body reserves of roosting great tits in relation to their dominance statu
Cation exchange chromatography has been routinely used for the quantification of monoclonal antibody (mAb) charge heterogeneity. A previously developed method utilizing pH gradients for the elution instead of salt gradients was validated according to current guidelines proposed by the ICH. The linearity, stability, accuracy, precision and the lower limit of quantification have been determined, usi
BRCA1 mutation carriers have up to 80% life-time risk of developing breast cancer and 20-40% risk of developing ovarian cancer. High LH levels have been linked to increased risks of both breast and ovarian cancers in some studies and it is unknown whether gonadotropin levels are associated with BRCA1 mutation status. The aim of the study was to explore whether gonadotropin levels were associated w
In this study, we investigated the interaction of fengycin, a lipopeptide produced by Bacillus subtilis, with lipid monolayers using the Langmuir trough technique in combination with Brewster angle rnicroscopy. Thermodynamic analyses were performed to get further information about the mixing behavior and the molecular interactions between the two components. The effect of fengycin on the structura
The aim of this qualitative study was to explore older persons' experience of participation in and influence on decisions about public home help/care when undergoing needs assessment and receiving public home help. A purposive sample of 28 home help recipients over the age of 75 were selected. Data were collected by means of in-depth interviews. A content analysis revealed one overarching category
Background The national hip registers of the Nordic countries provide an opportunity to compare age- and sex-standardized annual incidence of primary total hip replacement (THR) and types of implants used for primary hip osteoarthritis (OA) in Denmark, Finland, Iceland, Norway and Sweden. Methods The data on THR were from the national total hip replacement registries, and population data were from
A new binaphthalene molecule with two spiropyran units used for chiral molecular switches and logic gates was synthesized and chaxacterized.(12) In this paper, charge and energy transfer in binaphthalene molecule with two spiropyran units are theoretically investigated with quantum chemistry method, as well as 2D and 3D real space analysis methods, since molecule construction with photoinduced ele
Enzymes adsorbed or deposited on porous support materials have been succesfully used as catalysts in organic media. However, the support must be chosen with great care. The support can affect the partitioning of substrates, products and water in the reaction mixture and thereby indirectly influence the catalytic properties of the enzyme. Furthermore, the support can influence both the enzyme kinet
A model system consisting of pure triolein and palmitic acid and LipozymeTM, an immobilized lipase (E.C. 3.1.1.3.). has been used to determine the effects of various reaction parameters on the reaction rate and the formation of by-products in the interesterification reaction. The goal was to minimize the level of diglycerides and eliminate trisaturated triglycerides at an endpoint chosen so that t
Reduction of energy use in buildings is fundamental for sustainable development. A computer program for the prediction of energy use in buildings was assessed by comparisons with the energy performance of existing buildings. The program was then used to evaluate the energy saving characteristics of concrete such as air tightness and heat capacity. The impacts on global environmental aspects and li
År 2019 introducerade EU det så kallade visselblåsardirektivet. Direktivet tillkom för att komma till rätta med oegentligheter på den inre marknaden och stärka skyddsnivån för visselblåsare. Till följd av direktivets nya krav och bestämmelser behövde samtliga medlemsstater i EU ändra sin nationella lagstiftning på området. Enligt direktivet ska varje rättslig enhet med 50 eller fler arbetstagare hIn 2019, the EU introduced the so-called Whistleblower Directive. The directive was established to address misconduct in the internal market and strengthen the level of protection for whistleblowers. As a result of the directive's new regulations, all EU member states needed to amend their national legislation in this area. According to the directive, every legal entity with 50 or more employe
I december 2023 kom HD:s avgörande i PFAS-målet, där frågan om förhöjd risk för framtida skada kan utgöra personskada ställdes på sin spets. HD uttalade att det strider mot det traditionella synsättet att klassa en ren förhöjd risk som en personskada. Höga halter av PFAS i blodet bedömdes däremot utgöra personskada eftersom de höga halterna innebär en beaktansvärd kroppslig försämring. UppställandIn December 2023, the Swedish Supreme Court ruled in the so called PFAS case, in which the question of whether an increased risk of future harm can constitute personal injury was put to the test. The court stated that it contradicts the traditional view to classify a mere increased risk as a personal injury. However, high levels of PFAS in the blood were deemed to constitute personal injury becaus
Voluntary Carbon Markets (VCM) have emerged with the intention of supporting decarbonisation and carbon dioxide removal solutions around the world. However, and despite a rapid growth, the motivations and preferences of the demand side to engage in with the VCM have not been thoroughly studied before. Iceland, the focus of this thesis, exemplifies this trend. To address this knowledge gap, this th
Prostate-specific antigen (PSA) is a glycoprotein produced by the prostate gland. It occurs in several molecular forms in the blood and assays have been developed to measure free PSA and PSA in complex with alpha-1-antichymotrypsin (PSA-ACT). Higher proportions of free PSA (PSA-F/T) in blood are found in subjects with benign prostatic hyperplasia (BPH) as compared to cancer patients. Utilizing imm
