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Chemogenetics is the process of genetically expressing a macromolecule receptor capable of modulating the activity of the cell in response to selective chemical ligand. This chapter will cover the chemogenetic technologies that are available to date, focusing on the commonly available engineered or otherwise modified ligand-gated ion channels and G-protein-coupled receptors in the context of neuro
Introduction TCP-25 gel is intended for use in treatment of wound infection and inflammation. Current local therapies for wounds have limited efficacy to prevent infections and there are no wound treatments available today that target the excessive inflammation that often hampers wound healing in both acute and chronic wounds. There is therefore a high medical need for new therapeutic alternatives
This study investigates the effect of different mixers and the applicability of the mixing energy (ME) concept to dry powder formulations for inhalation. With the aim to step-wise build and expand this concept, adhesive mixtures of 2 % budesonide and lactose carrier were investigated, both with 1 % magnesium stearate (MgSt) added in a ‘coating’ step, and without, the latter referred to as ‘naked’
This contribution examines the evolution of public support for the euro since its introduction as a virtual currency in 1999, using a unique set of data not available for any other currency. We focus on the role of economic factors in determining the popularity of the euro. We find that a majority of citizens support the euro in each individual member country of the euro area (EA). The economic cr
This thesis aims to determine whether there is a human right to education in mother tongue for national minorities in international as well as regional human rights law. Its goal is to contribute to the existing research by evaluating and assessing the available treaties as well as non-binding documents issued by United Nations, Council of Europe and Organization for Security and Co-operation in E
RAINBOW är ett familjeorienterat kognitivt beteendeterapeutiskt behandlingsprogram som ges i gruppformat med parallella grupper för ungdomar 13 - 18 år med bipolärt syndrom (BPS) och deras föräldrar. Den svenska versionen av RAINBOW har nyligen förstärkts med familjesamtal. I föreliggande studie intervjuas tre ungdomar med BPS och deras tre föräldrar med syftet att undersöka upplevelser av deltagaRAINBOW is a family-oriented cognitive behavioral therapy program that is given a in group format with parallel groups for adolescents 13 - 18 years of age with bipolar disorder (BPS) and their parents. The Swedish version of RAINBOW has recently been enhanced with family sessions. In this study, three adolescents with BPS and their three parents are interviewed with the purpose of investigating e
This paper investigates the experience of inspiration by cultural workers in the art field. It takes a closer look at the research within the field so far and compares the everyday view of inspiration with theories researched about it as a concept. Identifying that there is a gap between how the term is used in everyday language and how science within psychology and other academic fields choose to
The current use of pesticides in Burkina Faso has been described as problematic. An alternative to synthetically produced pesticides is products based on naturally occurring substances, e.g. from plants, so-called biopesticides. In this study aqueous and ethanol extracts from Eucalyptus camaldulensis collected at three different geographical locations in Burkina Faso are investigated with regard t
FORMOX™ is a formaldehyde production process, utilizing a metal oxide catalysts. The new generation of plants is pressurized, therefore the turbo charger concept has been developed. This concept deploys a turbine coupled to a compressor, where the turbine recovers a substantial part of the electric power needed to run the compressor, from the outlet of the emission control system unit (ECS) in the
2018 publicerade UNESCO en uppdaterad version av deras rapport International Technical Guidance on Sexuality Education som släpptes 2009. Enligt UNESCO var en av anledningarna till att uppdatera rapporten en utökad medvetenhet om inkludering av genusperspektiv i utbildningen. I denna studie har två av rapporternas så kallade “Key Concepts”, där rekommendationer till ämnen och utformning av sexualu
The aim of this thesis is to discover how ideals about women’s workers’ identity regarding to bildning (workers’ education), class and organization are produced and constructed within the Swedish socialist journal Morgonbris (i.e. Morning Breeze) 1904–1916. The journal was first published within the labor union of women in Sweden, and was later on intertwined with the Social democratic women’s lea
EU som institution har präglats av beskrivningar av att vara ett neo-liberalt projekt. Tidigare forskning anlägger att det dock finns premisser för en ideologisk förändring. Genom konstaterande av samverkan mellan det ekonomiska systemets utfall och dess konstruktion är det möjligt att hypotetisera att finanskrisen som drabbade Europa 2007–2008 kan ha haft en inverkan på den ekonomiska politiken.
The aim of this report was to investigate the prominence effect as an underlying reason for saved-lives insensitivity in moral decision-making. Saved-lives insensitivity, the tendency to help fewer rather than more victims, causes unnecessary suffering. Why this tendency occurs is still unknown, but the prediction of this study was that the prominence effect is an underlying mechanism. The promine
As the world is becoming more digital, the use of data is rapidly increasing. To protect all EU citizens from privacy and data breaches, the regulations will become stricter. The General Data Protection Regulation (GDPR) will become effective on the 25th of May 2018. This will mean big structural changes for organizations, but it will also mean tougher requirements for gathering and maintaining pe
The benefits of economic growth (e.g. capital accumulation) are mainly being enjoyed by people in the Global North, while its negative byproducts (e.g. pollution) are mainly being endured by people in the Global South. Our focus on economic growth has led to the erosion of social wellbeing. And continuing economic growth on this planet with finite natural resources could have even more severe cons
This paper studies the relationship between contraceptive adoption by women and three relevant predictors: women’s education, empowerment and religious affiliation. I employ recent information on women’s characteristics and the institutional environment for six Latin American countries, in the years 2013-2015, to perform a cross-section analysis with binary and multinomial logistic regressions, ha
Det sker en förändring inom turistbranschen idag där traditionella källor till information som turistbyråer och destinationers besökshemsidor läggs ned och städer istället satsar på sociala medier som TripAdvisor för att ge turistinformation. På grund av den förändring som nu sker har vi valt att göra en kvantitativ undersökning över i vilken grad TripAdvisor används och anses som en pålitlig käll
