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As the global energy transition progresses, a range of drivers and barriers will continue to shape consumer attitudes and behavioural intentions towards emerging low-carbon technologies. The innovation-decision process for technologies composing the residential sector such as hydrogen-fuelled heating and cooking appliances is inherently governed by the complex interplay between perceptual, cogniti
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Arid mountainous regions are vulnerable to extreme hydrological events such as floods and droughts. Providing accurate and continuous rainfall records with no gaps is crucial for effective flood mitigation and water resource management in these and downstream areas. Satellite data and geospatial interpolation can be employed for this purpose and to provide continuous data series. However, it is es
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INTRODUCTION: We sought to harmonize genotype data from the predementia AMYPAD (Amyloid Imaging to Prevent Alzheimer's Disease) Consortium, compute polygenic risk scores (PRS), and determine their association with global amyloid deposition. METHODS: Genetic data from five AMYPAD parent cohorts were harmonized, and PRS were computed for Alzheimer's disease (AD) susceptibility, cerebrospinal fluid (
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Sorption-enhanced steam reforming (SorESR) is an advanced thermochemical process integrating in-situ CO2 capture via solid sorbents to significantly enhance hydrogen production and purity. By coupling CO2 adsorption with steam reforming, SorESR shifts the reaction equilibrium toward increased H₂ yield, surpassing the limitations of conventional steam reforming (SR). The efficacy of SorESR critical
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During 2024, an intensive 114CO2 flask sampling campaign was conducted at 12 sampling stations across Europe as part of the CO2MVS Research on Supplementary Observations (CORSO) project. These 114CO2 samples, combined with CO2 atmospheric measurements, are intended to enhance the estimation of fossil CO2 emissions over Europe through inverse modeling. In this study, we perform a series of Observin
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International guidelines recommend PET-CT should replace CT in Hodgkin Lymphoma (HL). The aims of this study were to i) compare PET-CT with CT for staging and ii) measure agreement between expert and local readers, using a five-point scale (Deauville criteria), to adapt treatment in a clinical trial 'Response Adapted Therapy in Advanced Hodgkin Lymphoma' (RATHL) www.cancer.gov/clinicaltrials, refe
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The increasing demand for software project managers in industry requires strategies for the development of the management-related knowledge and skills of the current and future software workforce. Although several approaches help teach the required skills in a university setting, few empirical studies are currently available to characterize and compare their effects. This paper presents results of
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Right ventricular rupture, resulting in serious bleeding, is a life-threatening complication associated with negative-pressure wound therapy (NPWT) in cardiac surgery. The use of a rigid barrier between the heart and the sharp sternal edges has been successfully tested on pigs. In the present article, we demonstrate increased safety in NPWT through the use of the HeartShield device.
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Correlations between heterozygosity and fitness are frequently found but rarely well understood. Fitness can be affected by single loci of large effect which correlate with neutral markers via linkage disequilibrium, or as a result of variation in genome-wide heterozygosity following inbreeding. We explored these alternatives in the common buzzard, a raptor species in which three colour morphs dif
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Subungual exostosis is a benign bone- and cartilage-forming tumor known to harbour a pathognomonic t(X;6)(q22;q13-14). Using global gene expression analysis and quantitative real-time PCR we could show that this translocation results in increased expression of the IRS4 gene, presumably due to disruption and/or exchange of regulatory sequences with the translocation partner, the COL12A1 gene. A cor
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The present article researches the mechanisms suggested for controlling the fulfillment of the EU sustainability criteria for transport biofuels that have been presented in the central legal framework in this area, which is Directive 2009/28/EC. The analysis is extended to the related EU policy documents of a non-binding explanatory and recommendatory character. Judging from the content of Directi
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To determine if type III collagen is concentrated in the chymotrypsin-extractable collagen pool from osteoarthritic articular cartilage to assess its potential as a biomarker of Osteoarthritis (OA) pathogenic mechanisms.
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Laminin (Ln) and collagen are multifunctional glycoproteins that play an important role in cellular morphogenesis, cell signaling, tissue repair and cell migration. These proteins are ubiquitously present in tissues as a part of the basement membrane (BM), constitute a protective layer around blood capillaries, and are included in the extracellular matrix (ECM). As a component of BMs, both Lns and
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Reviews the book, The theatre of trauma: American modernist drama and the psychological struggle for the American mind by M. Cotsell (2005). The author's main thesis is that American modernist dramaturgy was mostly propelled by representations of trauma and the ensuing dissociation, contrary to the usual interpretation that it was powerfully influenced by Freudian Oedipal theory of infantile sexua
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The capability of retrieving spectral information from line shapes recorded by two-tone frequency-modulation spectroscopy (TTFMS) is investigated. A TTFMS theory accounting for dispersion and nonlinear distortion of diode laser frequency modulation response is presented. The adequacy of the theory for a detailed modeling of line shapes recorded with high resolution is examined. An extensive error
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A modified local error model is developed for numerical integration of ODEs with invariants. The basic idea is to use a commutativity relationship that holds for implicit state-space form methods. A new implicit state-space form predictor is developed from which error estimates can be obtained by predictor-corrector difference: This technique is demonstrated through the preliminary examples in thi
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Macroporous scaffolds composed of chitosan and using oxidized dextran as a crosslinker are produced through cryogelation. Introducing gelatin as a third component into the structure results in the formation of mesopores in the pore walls, which are not seen if gelatin is excluded. The mesoporous structure is explained by the formation of polyelectrolyte complexes between chitosan and gelatin befor
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Phosphoproteomics relies on methods for efficient purification and sequencing of phosphopeptides from highly complex biological systems, especially when using low amounts of starting material. Current methods for phosphopeptide enrichment, e.g., Immobilized Metal ion Affinity Chromatography and titanium dioxide chromatography provide varying degrees of selectivity and specificity for phosphopeptid
