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Purpose: Improvements in mortality rate of glioblastoma patients have been limited during the past decades, due to the tumor’s rapidly growing and infiltrative behavior and resistance to current therapy. Recent findings show that higher brain mean dose strongly correlates with inferior overall survival and that local recurrences mainly occur centrally in previously irradiated regions. This project
Bakgrund: Prokrastinering är uppskjutande av utförande av aktivitet trots vetskapen om att det kan ge negativa konsekvenser i längden. Det är ett fenomen som är väl beforskat inom den vetenskapliga disciplinen psykologi men i stort sett outforskat inom arbetsterapin och aktivitetsvetenskapen. Syfte: Syftet med denna studie var att kartlägga prokrastinering samt förekommande behandlingar ur ett aktBackground: Procrastination is the postponement of performance of an activity despite the knowledge that it can have negative consequences in the long run. It is a phenomenon that is well researched in the scientific discipline of psychology but largely unexplored in occupational therapy and occupational science. Aim: The aim of this study was to map procrastination and existing treatments from th
Popular Abstract in Swedish De två vanligaste typerna av neurodegenerativ demenssjukdom är Alzheimer’s sjukdom och Lewy body demens. Båda sjukdomarna drabbar framförallt äldre människor och risken att insjukna ökar med stigande ålder. Detta innebär att demenssjukdom kommer att bli vanligare i samhället, eftersom vi blir allt äldre och andelen invånare >65 år blir allt större. Att drabbas av demensBackground: A prognostic marker should provide information about course and outcome of disease, e.g. predict time to a given endpoint or rate of progression due to disease in patients or subgroups of patients. Prognostic markers could be targeted to apply during the entire clinical course or just during distinct stages of the disease. Aim: The aim of this thesis is to identify, review and qualif
Understanding Sense Perception We all need to perceive sensations such as pain; cold or pungent chemicals in order survive. In elucidating sense perception, we investigate TRPA1 which is a major player in sensation. Transient Receptor Potential (TRP) is a large family of ion channels that are found in membrane of biological cells. They were first discovered in fruit fly in 1969 and this discovery
Inom kärnkraftsverken, läkemedelsindustrin, biotekniklaboratorier mfl är det vanligt att det radioaktiva ämnet 14C förekommer i olika former. Inom kärnkraftsverken som en biprodukt vid elproduktion och inom läkemedelsindustrin används det som markör för att studera hur sunbstansen distribueras i kroppen. Genom inandning vid t ex oförsiktighet kan de människor som arbetar med dessa olika substanserWith the help from accelerator mass spectrometry (AMS), hair from workers within the nuclear power industry, pharmaceutical and biotechnology industry has been investigated to see if contamination from 14C. 14C-using companies and nuclear power plants were contacted, volunteers were recruited, who sent in hair samples together with a questionnaire. The samples were washed and prepared for 14C anal
Massive multiple-input multiple-output (MIMO) refers to a wireless access technology that equips base station (BS) with hundreds to thousands of antennas to serve tens of user equipment (UE) in the same time-frequency resource. These extensive antennas improve spectral and energy efficiency, but the detection algorithms tend to be more complex with operations, multiplications, and inversions on la
Natural food webs are embedded in a variable environment, which causes population densities to fluctuate, despite a potential stable equilibrium. Population interactions as well as the characteristics of the environmental fluctuations determine the resulting population dynamics. Populations sensitive to the same kind of environmental disturbances will show correlated responses in their respective
Popular Abstract in Swedish Den här avhandlingen behandlar hur fettdroppar i mjölk slås sönder i en mjölkhomogenisator. Mekanismerna bakom sönderslagningen har analyserats genom uppmätning av flödesfältet i spalten samt genom att fotografera dropparna, när de slås sönder. För att möjliggöra mätning och fotografering har två skalmodeller av en homogenisator tagits fram. En fullskalemodell, vilken The overall aim of this project was to investigate the drop break-up process in milk homogenisers. This was done by measurements and calculations of the flow fields in the gap region and by visualisation of drops being broken up. To make visualisation and measurements possible, two scale models of a homogeniser gap were developed. The full-scale model was a direct copy of the gap in a production-
BACKGROUND: Elevation of haemoglobin (Hb) with recombinant erythropoietin (rHuEpo) in patients with chronic renal failure has raised concern of increased risk of thromboembolic diseases. In this study, a substudy of the Scandinavian multicentre trial, we examined the influence on haemostatic parameters of normalization of Hb levels from subnormal levels in patients with chronic renal failure.METHO
In this paper we report the linear and non-linear optical properties of metallic nano-clusters in α-Al 2O 3 fabricated by ion implantation (from 2 to 8×10 16 ions/cm 2). Thereafter, the samples were annealed at temperatures from 600 to 1100°C in oxidising, reducing atmospheres. Once spherical nano-particles were synthesized, the samples were further irradiated with Si +++ with different energies a
STUDY OBJECTIVES: The aim was to evaluate nasal polyposis as a risk factor for nonadherence to continuous positive airway pressure (CPAP) treatment in patients with obstructive sleep apnea (OSA). METHODS: This was a population-based, longitudinal analysis of patients starting CPAP treatment for OSA in the Swedish quality registry Swedevox between 2010 and 2018. Data were cross-linked with national
The photofunctionality of the cobalt-hexacarbene complex [Co(III)(PhB(MeIm)3)2]+ (PhB(MeIm)3 = tris(3-methylimidazolin-2-ylidene)(phenyl)borate) has been investigated by time-resolved optical spectroscopy. The complex displays a weak (φ ∼10-4) but remarkably long-lived (τ ∼1 μs) orange photoluminescence at 690 nm in solution at room temperature following excitation with wavelengths shorter than 35
Increasing demand for detecting single molecules in challenging environments has raised the bar for the fluorophores used. To achieve better resolution and/or contrast in fluorescence microscopy, it is now essential to use bright and stable dyes with tailored photophysical properties. While long fluorescence lifetime fluorophores offer many advantages in time-resolved imaging, their inherently low
We obtained 10/192 and 3/384 antibody-secreting hybrids after immunization of Balb/c mice with either human growth hormone or affinity-purified rabbit anti-(human growth hormone) respectively. Radiolabelled rabbit anti-(human growth hormone) antibodies, but not human growth hormone, were specifically bound by supernatants from the 13 hybrids. The binding was completely inhibited by human-growth-ho
A combustion Large Eddy Simulation (LES) is used to examine the flow, mixing, fuel-injection and combustion dynamics of a ramjet combustor with a cavity flame holder. The combustor is a running 50/50, in mole, ethylene/hydrogen fuel mixture. A direct-connect facility dual-mode ramjet/scramjet combustor presents the target case, with in the literature available experimental data is used in the pres
