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A cultivation strategy for the production of two truncated thermostable recombinant xylanases (Xyn1ΔN and Xyn1ΔNC) was developed. Fed-batch cultivations of Escherichia coli strain BL21(DE3) with a controlled exponential glucose feed led to high specific production of the recombinant proteins. Addition of complex nutrients (e.g. Tryptone Soya Broth (TSB)) to the media were shown to increase both th

Much of the current work on third language acquisition focuses on modeling the impact from the speaker’s previous language(s). The Typological Primacy Model (Rothman, 2015), which covers holistic forward transfer at the initial state, and the L2 Status Factor (Bardel and Falk, 2012), which proposes forward transfer from a chronologically true L2, only predict effects on subsequently acquired langu

OBJECTIVE: Radical prostatectomy reduces mortality among patients with localized prostate cancer, however up to 35% of patients will experience biochemical recurrence, often treated with salvage radiotherapy. The objective of the study was to investigate long-term effects of salvage radiotherapy. METHODS: A prospective, controlled, non-randomized trial at 14 Swedish center's including 4,003 patien

Objectives: To evaluate the total number of false-positive recalls, including radiographic appearances and false-positive biopsies, in the Malmö Breast Tomosynthesis Screening Trial (MBTST). Methods: The prospective, population-based MBTST, with 14,848 participating women, was designed to compare one-view digital breast tomosynthesis (DBT) to two-view digital mammography (DM) in breast cancer scre

As in most cultural contexts and theoretical conceptualizations of peacebuilding, the fulfilment of justice and the sustainment of peace are intimately related in the Arab-Islamic frame of reference. In the Qur’an and Islamic philosophy, there is a direct correlation between establishing a just social order and the notion of peacebuilding (Abu-Nimer 2006). Guidelines are set forth for building a so

Purpose: The need for sentinel lymph node biopsy (SLNB) in clinically node-negative (cN0) patients is currently questioned. Our objective was to investigate the cost-effectiveness of a preoperative noninvasive lymph node staging (NILS) model (an artificial neural network model) for predicting pathological nodal status in patients with cN0 breast cancer (BC). Methods: A health-economic decision-ana

Departing from the hypothesis that R&D within ICT plays an essential role in the transformation of the construction sector from a traditional to an industrialised process, a joint Swedish and French project has been carried out (to be completed in April 2007) to assess the short and medium term possibilities to improve efficiency and quality in multi-storey house-building. This paper describes

Understanding Sense Perception We all need to perceive sensations such as pain; cold or pungent chemicals in order survive. In elucidating sense perception, we investigate TRPA1 which is a major player in sensation. Transient Receptor Potential (TRP) is a large family of ion channels that are found in membrane of biological cells. They were first discovered in fruit fly in 1969 and this discovery

Low-complexity VLSI (very large scale integration) architecture of the square root algorithm is proposed for MIMO (multiple-input multiple-output) detection. As a modification to the traditional QR triangular array based architecture, the proposed architecture significantly reduces the area and power consumption with virtually no performance or throughput degradation. The finite word length effect

Background and purpose: The Radiation Oncology Safety Information System (ROSIS) was established in 2001. The aim of ROSIS is to collate and share information on incidents and near-incidents in radiotherapy, and to learn from these incidents in the context of departmental infrastructure and procedures. Materials and methods: A voluntary web-based cross-organisational and international reporting an

Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen bland kvinnor i Sverige. Ungefär var tionde kvinna beräknas drabbas av bröstcancer, och i Sverige insjuknar ungefär 7.000 kvinnor årligen. Glädjande nog har överlevnaden förbättrats och nästan 90% lever 5 år efter sin diagnos och cirka två tredjedelar kan anses botade. Trots detta dör cirka 1.500 kvinnor i sjukdomen i Sverige vBreast tumours harbour a large amount of genetic and epigenetic alterations, which are associated with e.g. tumour aggressiveness, prognosis, and response to therapy. The heterogeneity of breast tumours is reflected in the identification of at least five molecular subtypes named basal-like, luminal A, luminal B, HER2-enriched and normal-like, which are believed to originate from different cell typ

BACKGROUND: Gastrectomy (Gx) causes osteopenia. The hypothesis tested in the present study is that Gx affects Ca homeostasis and that an impaired ability to handle Ca contributes to the Gx-evoked osteopenia. METHODS: SHAM-operated and Gx rats were compared with respect to changes in blood Ca2+ after oral or intravenous loads of CaCl2 1-2 weeks or 2-4 months after the operations. RESULTS: Different

Popular Abstract in Swedish Ett nytt EU-direktiv om uttjänta fordon har nyligen antagits. Direktivet kräver att från och med 2006 skall 85% av bilens vikt återvinnas och 95% från och med år 2015. Idag återvinns cirka 80%. Bildemonteringsindustrin har valts som studieobjekt i denna avhandling. De höjda återvinningskraven förväntas leda till att bildemonteringsindustrin genomgår omfattande rationaliA new EU directive on used vehicles has recently been introduced. It demands that for every scrapped car, at least 85% by weight must be recycled by the year 2006 and 95% by 2015. The current level is about 80%. The car disassembly industry was chosen as the study object of this thesis. Due to the increased demands on recycling, the disassembly industry may undergo comprehensive rationalizations a