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Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly
The aim of the work presented in this thesis was to improve the management of infections in immunocompromised patients by studying aspects of diagnostics, epidemiology and nosocomial transmission. Infection and rejection are common complications in lung-transplant patients, and early diagnosis and treatment are important for a positive outcome. In a study of lung-transplant patients it was found t
Det beräknas att cirka 50 miljoner människor världen över har en demenssjukdom mot förväntade 152 miljoner år 2050 och enligt WHO är demenssjukdomar en prioriterad hälsopolitisk fråga. Primärvårdsläkares roll i upptäckt och behandling av tidig demens är troligen hälsoekonomiskt fördelaktig men primärvårdens handläggning av patienter med förmodad demens varierar stort. Syftet med denna avhandling vBackground: Around 50 million people worldwide have dementia and the prevalence is expected to increase to 152 million by 2050. According to the WHO, dementia is a priority health policy issue. The role of primary care physicians (PCPs) for timely dementia management can be cost-effective, yet PCP involvement in the management of patients with presumed or diagnosed dementia vary across Europe.Aim:
Although the communication aspects of sport and football organizations are receiving in-creased scholarly attention, research from the perspective of fans of such organizations has mostly been neglected. This study problematizes the gap that exists be-tween the current social media communication of football organizations, that tend to be guided by commercial interests, and the expectation of fans
