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BACKGROUND: Risk factors for suicide and fatal accidental intoxication are extensively studied, while risk factors for intoxications/injuries of undetermined intent are less well known. The latter have shown an overlap with suicides, but also with fatal accidental intoxications. The objective was to analyze potential differences and similarities in the patterns of risk factors for accidental intox
The responses to step and pulse transients with reactants have been simulated for conventional step-transient conditions at atmospheric pressure and pulsing under vacuum using a temporal analysis of products (TAP) reactor, respectively. Propene oxidation over an oxide catalyst with the participation of lattice oxygen was chosen as a model reaction. The mechanism comprises adsorption of the reactan
Using two epochs of HST/WFPC2 images of the metal-rich globular clusterNGC 6528 we derive the proper motions of the stars and use them toseparate the stars belonging to NGC 6528 from those of the Galacticbulge. The stellar sequences in the resulting colour-magnitude diagramfor the cluster are significantly better determined than in previouslypublished data. From comparison of the colour-magnitude
The goal of this research is to use hematopoietic cells as vehicles for targeting transgenic immunomodulators to the inflammatory sites. The work presented was focused on the anti-inflammatory soluble TNF receptor. A transmembrane soluble TNF receptor (sTNFR1) construct was expressed in hematopoietic cell lines. ER export was facilitated by addition of a transmembrane (tm) sequence, and constituti
BACKGROUND: The clinically significant antigens of the Duffy (Fy [FY]) blood group system are expressed on the red cell form of the FY glycoprotein, a promiscuous chemokine receptor and also a receptor for malarial parasites. After the cloning of cDNA coding for FY glycoprotein, the molecular basis of the three major alleles (Fya/Fyb/Fy) has been established. Because of the mistyping of the silent
Low molecular weight protein tyrosine phosphatase (LMW-PTP) dimerizes in the phosphate-bound state in solution with a dissociation constant of K-d = 1.5(+/-0.1) mM and an off-rate on the order of 10(4) s(-1).H-1 and N-15 NMR chemical shifts identify the dimer interface, which is in excellent agreement with that observed in the crystal structure of the dimeric S19A mutant. Two tyrosine residues of
Grooming är ett vedertaget begrepp för det tillvägagångssätt som förövare använder sig av för att ta kontakt med barn, ofta på internet, för att slutligen begå sexuella brott mot barnet. Internetets expansion har på många sätt gett förövare fler tillvägagångssätt att komma i kontakt med barn. En stor andel av barnen i Sverige använder sociala medier, varav många någon gång har blivit kontaktade onGrooming is an established word for the approach that perpetrators are using to contact children, oftentimes over the Internet, ultimately to commit sexual offenses against the child. The expansion of the Internet has in many ways made it easier for perpetrators to approach and contact children. The vast majority of Swedish children use social media, many of whom at some point have been contacted
Behavior and social interactions are key features to determine the phenotype of an organism. Observing behavioral manifestations give insides on a fundamental level of how inner mechanisms work. But how is it possible to predict behavior in a way, such that it can be quantify and analyzed? One traditional strategy is to annotate the behavior by hand. Observing the animals and making notes about th
To stay within our planet’s limits and reach the United Nation’s Sustainable Development Goals, there is an urgent need to rethink our current and dominant systems. This thesis focuses on the food system, in particular, and explores how an overarching turnaround in the way we produce and consume food has the potential to trigger and steer a greater transition towards sustainability. However, this
We hypothesised that the removal of the subchondral bone plate (SCBP) for cemented acetabular component fixation in total hip arthroplasty (THA) offers advantages over retention by improving the cement-bone interface, without jeopardising implant stability. We have previously published two-year follow-up data of a randomised controlled trial (RCT), in which 50 patients with primary osteoarthritis
The aim of this study was to investigate myocardial wall motion using echocardiography and color-coded tissue velocity imaging and to generate a cardiac state diagram for evaluation of the duration of the pre- and post-ejection phases in asphyxiated fetal lambs. Six near-term lambs were partly exteriorized and brought to cardiac arrest through asphyxia. Echocardiography measurements were recorded
A three-phase hollow fiber liquid phase microextraction (HF-LPME) method was evaluated for the extraction and preconcentration of naproxen and diclofenac using a polypropylene membrane followed by analysis using HPLC or LC/MS. In this technique, the drugs were extracted into di-n-hexyl ether immobilized in the wall pores of a porous hollow fiber from 50mL of sludge slurry sample as a donor phase w
We aimed to study differences in the prescribing of warfarin, aspirin and statins to patients with atrial fibrillation (AF) in socio-economically diverse neighborhoods. We also aimed to explore the effects of neighborhood deprivation on the relationship between CHADS2 risk score and warfarin prescription.
Rapid urban growth has brought along various social, economic, and environmental issues, including the expansion of informal settlements – deprived areas lacking proper housing, basic services, and safety. Informal areas, inequalities and exclusion are common features in Nairobi, where more than half of the population is residing in slums. Women are the most vulnerable in this context, struggling
In a changing world order, emerging middle powers from the global South may seek new positions in international societies. Using the United Nations as an international society, this thesis aims to investigate what roles the emerging middle powers, Brazil and South Africa, enact in pursuing permanent seats at the Security Council. This research conducts a qualitative text analysis using official da
The production and use of chemicals has grown exponentially over the past 50 years. Although the knowledge of hazards and risks associated with chemicals towards humans and the environment has increased, we know frightenedly little about how dangerous these might become when part of finished products. Companies now need to be more concerned about which chemicals exist in their products. For the co
Den tekniska utvecklingen och förändrade arbetsformer gör att det i dag är enklare än någonsin för arbetsgivare att kontrollera och övervaka arbetstagare. Under senare år har det blivit allt vanligare att arbetsgivare övervakar arbetstagares elektroniska kommunikation. Med elektronisk kommunikation avses arbetstagares kommunikation via användningen av arbetsgivares IT-utrustning och internetanslutDue to technical developments and changed forms of working, it is now easier than ever for employers to control and monitor employees. In recent years, it has become increasingly common for employers to monitor employees’ electronic communications. Electronic communication refers to employee communication via the use of the employer’s IT equipment and internet connection. The most prevalent form o
Humanitarian crises are becoming more frequent- and increasingly protracted, causing humanitarian actors to be under mounting pressure in their attempts to respond to the increasing amount of people in need. Among else, cash-based programming has been highlighted as part of the solution to this and has been rapidly on the rise as an aid modality among humanitarian actors in the past few years. Whi
Border carbon adjustment is an economic instrument being discussed more frequently as a possible solution to address carbon leakage, which is an issue for many developed countries. Developed countries are showing interest in this instrument to protect domestic industries from carbon leakage to countries that do not tax carbon. There is however concerns from developing countries that border carbon
