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Human fetal mesencephalic dopamine (DA) neurons, obtained from 6.5-9 week old aborted fetuses, were grafted to the striatum of immunosuppressed rats with 6-hydroxydopamine lesions of the ascending mesostriatal DA pathway. The effects on amphetamine-induced motor asymmetry were studied at various timepoints after grafting. At eight weeks, functional graft effects were not evident but after 11 weeks
Active surveillance (AS) is broadly described as a management option for men with low-risk prostate cancer, but semantic heterogeneity exists in both the literature and in guidelines. To address this issue, a panel of leading prostate cancer specialists in the field of AS participated in a consensus-forming project using a modified Delphi method to reach international consensus on definitions of t
A new model-free method is presented that automatically corrects for phase shifts, frequency shifts, and additional lineshape distortions of one single resonance peak across a series of in vivo NMR spectra. All separate phase and frequency variations are quickly and directly derived from the common lineshape in the data set using principal component analysis and linear regression. First, the new a
Introduction and hypothesis: The objective was to compare the effect of antibiotics versus no antibiotics prophylaxis per-operatively on the frequency of urinary tract infection (UTI) following mid-urethral sling application to treat stress or mixed urinary incontinence. Methods: This study was designed as a multicenter prospective randomized trial. Women were included from eight centers in three
Measurements of differential production cross-sections of a Z boson in association with b-jets in pp collisions at root s = 7 TeV are reported. The data analysed correspond to an integrated luminosity of 4.6 fb(-1) recorded with the ATLAS detector at the Large Hadron Collider. Particle-level cross-sections are determined for events with a Z boson decaying into an electron or muon pair, and contain
Introduction: Flexible Assertive Community Treatment (FACT) is implemented in Swedish general Mental Health Services. While FACT focuses on supporting the participation and personal recovery of individuals with complex mental health needs, critical components enabling these aspects are poorly understood. The aim of this study was to understand the critical components of FACT delivery supporting pa
Post-translational modifications (PTMs) such as nitration of Tyr (Y) residues and di-tyrosine (DT) formation are known to impact the aggregation behavior of α-synuclein (α-syn), a protein closely linked to Parkinson's disease. Using tetranitromethane (TNM) as a model nitrating agent, we systematically investigated the chemical modifications of α-syn and their consequences for aggregation. Mass spe
This paper presents findings from a transdisciplinary study exploring conditions for Inclusive Science Education (ISE) for children aged 0–16 from communities in vulnerability risk situation. A two-step literature review was conducted to identify inclusive teaching and learning interventions. The first phase applied a Scoping Review, followed by an Integrative Literature Review focusing on communi
The present study aimed to increase understanding of how singing activities may be initiated in primary school, and what support and assistance teachers require to conduct singing activities as an integrated part of the school day. Five music teachers participated in a focus group interview. The following main themes were identified: 1) pedagogical and methodological flexibility, 2) the role of ro
A set of measurements for the production of a W-boson in association with high-transverse-momentum jets is presented using 140 fb-1 of proton–proton collision data at a centre-of-mass energy of s=13 TeV collected by the ATLAS detector at the LHC. The measurements are performed in final states in which the W-boson decays into an electron or muon plus a neutrino and is produced in association with j
Background: Blood cultures (BCs) are key diagnostic elements for sepsis patients. Accurate preanalytical procedures are substantial, and results should be available as soon as possible to guide adequate antimicrobial treatment. This study aimed to evaluate BC collection practices and diagnostic capacity across European hospitals. Methods: This cross-sectional survey investigated BC diagnostics in
Background: Repetitive and monotonous work is often associated with neck pain, potentially resulting in sick leave and reduced productivity. Establishing appropriate muscle activity patterns, including duration and frequency of breaks that can prevent neck pain development, is important for providing workplace guidance. While several smaller studies addressing monotonous neck-loading work have ind
Background: Less adults with cerebral palsy (CP) lives independently, compared to adults without disabilities. Access to personal assistance may help overcome barriers to independent living. Also, little is known about hand function in adults with CP, and the role of hand function in achieving independent living remains unexplored. Objective: To explore the associations between housing and persona
Objective: To develop machine-learning models that incorporate clinical information and radiomics features extracted from ultrasound images to distinguish uterine sarcomas from leiomyomas. Methods: This retrospective, multicenter, pilot case–control study included 200 patients (100 with a uterine sarcoma and 100 with a usual-type leiomyoma, i.e. including no benign leiomyoma variants) who underwen
Purpose: Genital malformations are increasingly recognized when a VACTERL is present, but remain insufficiently described in children with esophageal atresia (EA). This study aimed to determine the prevalence and spectrum of genital and urinary tract malformations in children with EA, and to describe associated morbidity, need for additional surgery, and association with Gross classification. Meth
This systematic review and meta-analysis of individual patient data evaluates the outcomes of treatment for Dupuytren's disease using limited fasciectomy (LF), percutaneous needle fasciotomy (PNF) and collagenase clostridium histolyticum (CCH) injection. A total of 1423 studies were identified, of which 15 met the eligibility criteria for meta-analysis. The postoperative total extension deficit wa
This study provides a systematic overview of Natural Language Processing (NLP)-based frameworks for Cyber Threat Intelligence (CTI) and the early prediction of cyberattacks in Industry 4.0. As digital transformation accelerates through the integration of IoT, SCADA, and cyber-physical systems, manufacturing environments face an expanding and complex cyber threat landscape. Following the PRISMA 202
Background: The diagnostic performance of the IOTA methods, the O-RADS lexicon, and the RMI has been validated in prospective and retrospective studies, but most validation studies tested the performance in the hands of experienced ultrasound examiners. Objective: To prospectively validate the performance of the Risk of Malignancy Index, the International Ovarian Tumor Analysis Simple Rules Risk M
Title: Understanding the boost for knowledge sharing in the front-end: A single case study about motivation to cross-functional share knowledge in the front-end Date: May 2018 Course: ENTN39 Master’s Corporate Entrepreneurship and Innovation Internship and degree project (Master’s thesis 15 ECTS) Authors: Herslow, Carl-Johan & Wild, Max-Joseph Supervisor: Ass. Professor Shibayama, Sotaro Exam
