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Developing integrated downstream processes for next-generation biologics

Manufacturing of biopharmaceuticals is a costly and time consuming process due to its inherent complexity and variability. The downstream process is the most expensive part and it involves multiple non-trivial steps. Continuous integrated manufacturing is a new concept that is encouraged by authorities. The advantages include uninterrupted operation, automation, consistent product quality, lower r

HoloScale: horizontal and vertical scaling of cloud resources

Elastic and scalable compute resources are a fundamental part of cloud computing. Efficient management of cloud resources is crucial in order to provide high quality services and applications. In this work we present a novel method for scaling cloud resources and provide stability guarantees. We do this by leveraging ideas and concepts from classic control theory, namely mid-range control and comb

C–H activation through late transition metal cyclometallation. Addressing selectivity and reactivity problems.

The ligand-directed C—H activation relies on a coordinating donor atom being in proximity to the C—H bond activated. Cyclometallation of 2-(1-naphthyl)-pyridine – a substrate containing both γ- and δ-positions in proximity to the directing nitrogen atom – was studied. Cycloruthenation and cyclopalladation result in γ-substitution and formation of the corresponding 5-membered metallacycles, which i

Production of Perdeuterated Proteins in Escherichia coli for Structural Studies by Neutron Crystallography

Neutron macromolecular crystallography (NMX) is a complementary technique to X-ray crystallography leveraging neutron scattering properties of the hydrogen isotope deuterium (2H). Production of deuterium labelled molecules together with large crystal requirements for neutron crystallography are few of several bottlenecks limiting implementation of this technique for a wider range of proteins. Perd

Automatic Landing without GPS

Sagem Défense et Sécurité (now Safran Electronics & Defense), a French space and defense company of the SAFRAN group, is working on the next generation of Unmanned Aerial System (UAS). This UAS features a fully automatic Unmanned Aerial Vehicle (UAV) equipped with a state-of-the-art navigation system. This navigation system relies mainly on a high-accuracy Inertial Measurement Unit (IMU) coupl

Mven03 schema ht18 180608

MVEN03_Planering_HT18_180608.xlsx MILJÖVETENSKAP Preliminär planering/schema 180608 Kurs: MVEN03 ‐ Miljövetenskap: Analys och metodik, 15 hp  HT 2018 Kursansvarig: Nina Reistad NR nina.reistad@fysik.lth.se Lärare: Estelle Larsson EL estelle.larsson@med.lu.se Per Erik Isberg PEI  per‐erik.isberg@stat.lu.se Pål Axel Olsson PAO pal_axel.olsson@biol.lu.se Martijn van Praagh MVP   martijn.van_praagh@mv

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven03_schema_ht18_180608.pdf - 2026-05-29

Robust Multi-Objective Optimization of Chromatographic Rare Earth Element Separation

Rare earth elements are strategic commodities in many countries, and an important resource for the growing modern technology industry. As such, there is an increasing interest for development of rare earth element processing, and this work is a part of further development of chromatography as a rare earth element separation process method. Process optimization is pivotal for process development, a

Certainty and systematicity of practice-derived evidence matter for its relative importance in professional decision-making : Survey results on the role of proven experience in Swedish medicine, nursing, OT, dentistry, and dental hygiene

BackgroundHigh-quality healthcare decisions need to balance input from science and clinical practice. When two sources of evidence — such as scientific and practice-derived evidence — are compared, integrated, or need to stand-in for one another, they need to be comparable on similar dimensions. Since 1891, Swedish physicians have been operating under a legal requirement to base their healthcare d

Nadia Chaudhry - Institutionen för translationell medicin

13 juni 2025 13:00 | Halvtidskontroll Title: Explorative clinical studies of optical breast investigations  Main supervisor: Sophia Zackrisson (MD, PhD, Professor), co-supervisors Nina Reistad (PhD, Associate Professor) and Magnus Cinthio (PhD, Associate Professor). Reviewers: Neda Haj Hosseini, Associate Professor, Linköping University and Pernilla Peterson, PhD, Lund UniversityAbstractBackground

https://www.intramed.lu.se/evenemang/nadia-chaudhry-institutionen-translationell-medicin - 2026-05-29